CAS: 455280-00-9; 5-Bromobenzo[d]Isoxazol-3-Ylamine
该化合物是有机化合物,其特点是其杂交循环结构,其中包括一个与一个矿物质组结合的苯氧新诺明环;在苯氧新诺明的5个位置上存在一个溴原子,有助于其再活性并有可能应用于各种化学反应;该化合物通常由于存在可以进行氢结合的安咪功能组,在极地溶剂中表现出中等溶解性;该化合物经常用于医药化学和物质科学,用于其潜在的生物活动,包括抗微生物和抗癌症特性;该化合物的分子结构允许各种替代反应,使其在有机合成中成为多功能中间体;此外,受该矿物质组中溴亚化和氮原子影响的独特电子特性,可影响其在化学反应和与生物目标相互作用中的行为;应当参考安全数据,以便处理和使用,如任何化学物质一样,确保采取适当的预防措施.
相似化合物
1260860-32-9 177995-39-0 36216-80-5物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
CAS号546-88-3 乙酰氧肟酸 | CAS号179897-89-3 5-溴-2-氟苯腈合成工艺路线路线简述
📜5-Bromo-2-((Propan-2-Ylideneamino)Oxy)Benzonitrile 以 盐酸,三氟乙酸 作为反应溶剂,化学反应 16.0H,以to Give 5-Bromobenzo[d]Isoxazol-3-Amine (324 Mg,76% Yield)的收率获得产物3-胺基-5-溴苯并[d]异噁唑
参考文献:Aminotriazolopyridines,Compositions Thereof,And Methods Of Treatment Therewith
标题:Aminotriazolopyridines,Compositions Thereof,And Methods Of Treatment Therewith
摘要:本文提供了公式(i)的杂环芳基化合物:其中r1和r2如本文所定义,包含有效量的杂环芳基化合物的组合物以及用于治疗或预防炎症性疾病或癌症以及通过抑制激酶或激酶途径可治疗或预防的疾病的方法,包括向需要的受体中施用有效量的杂环芳基化合物.
专利信息
专利号:US-10995078-B2
优先权日:2013-03-13
标 题:Compounds and compositions for inhibition of FASN
发明人：BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
权利人:FORMA THERAPEUTICS INC
摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:
专利号:US-8178559-B2
优先权日:2004-12-30
标 题:Organic compounds
发明人：BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI
权利人:BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI; NOVARTIS AG
摘要:3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4substituted piperidine compound, a method for the manufacture of a 3,4-substituted piperidine compound, and novel intermediates and partial steps for their synthesis are disclosed. The 3,4-disubstituted piperidine compounds have the formula (I), wherein the symbols have the meanings defined in the specification.
