其它别名NON-4-ENE; TRANS-4-NONENE; 4-nonene(cis+trans); 4-Nonene,c&t; 4-NONENE; 4-Nonene (cis- and- trans- mixture); 4-nonene, mixture of cis and trans; 4-NONENE MIXTURE OF CIS AND TRANS
专利号:US-7247752-B2 优先权日:2004-10-01 标 题 :Methods for the synthesis of astaxanthin 发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID 权利人:CARDAX PHARMACEUTICALS INC 摘要:A method used for synthesizing intermediates for use in the synthesis of carotenoids and carotenoid analogs, and/or carotenoid derivatives. In some embodiments, the invention includes methods for synthesizing optically active intermediates useful for the synthesis of optically active carotenoids. Synthesis of optically active carotenoids, in one embodiment, may be accomplished by forming an optically active dihydroxy intermediate from ketoisopherone. The optically active dihydroxy intermediate may be converted into optically active astaxanthin derivatives.
专利号:US-5723619-A 优先权日:1997-01-13 标 题 :Method for the synthesis of deoxypyridinoline 发明人:HATCH ROBERT P 权利人:BAYER AG 摘要:Disclosed is a method for the chemical synthesis of deoxypyridinoline (DPD). The synthesis involves the preparation of a protected 3-hydroxypyridinium starting with a Nα-protected lysine and a 5,6-epoxy-2-N-protected-O-protected-(2S)-2-aminohexanoate with subsequent deprotection to provide the desired DPD.
专利号:US-10918627-B2 优先权日:2016-05-11 标 题:Convergent and enantioselective total synthesis of Communesin analogs 发明人:MOVASSAGHI MOHAMMAD; LATHROP STEPHEN PAUL; POMPEO MATTHEW W; CHANG WEN-TAU TIMOTHY 权利人:MASSACHUSETTS INST TECHNOLOGY 摘要:A highly convergent biomimetic synthesis of a complex polycyclic scaffold has been successfully implemented. From these efforts, compounds having a structure of Formula (I): n nor a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R 1 -R 8 and m, n, r, s, t, and u are as defined herein, is provided. Methods of making such compounds are also disclosed as are methods for the treatment of cancer, various infectious diseases, and abnormal cardiovascular function.
专利号:US-7435861-B2 优先权日:2005-04-29 标 题 :Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates 发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID 权利人:CARDAX PHARMACEUTICALS INC 摘要:A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.
专利号:US-2008221377-A1 优先权日:2006-06-16 标题 :Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates 发明人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID; BRAUN CRISTI L 权利人:LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID; BRAUN CRISTI L 摘要:A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.
专利号:US-8629288-B2 优先权日:2008-02-25 标题:Method for the regioselective synthesis of 1-alky1-3-haloalkyl-pyrazole-4-carboxylic acid derivatives 发明人:PAZENOK SERGII; LUI NORBERT; HEINRICH JENS-DIETMAR; WOLLNER THOMAS 权利人:PAZENOK SERGII; LUI NORBERT; HEINRICH JENS-DIETMAR; WOLLNER THOMAS; BAYER IP GMBH 摘要:The present invention relates to a process for the regioselective synthesis of 1-alkyl-3-halo-alkylpyrazole-4-carboxylic acid derivatives by cyclization of 2,3-disubstituted acrylic acid derivatives, and to the hydrazones formed as intermediates in the process.
参考标题:Quinoxaline Derivatives 摘要:The Synthesis Of Quinoxaline And Benzimidazole-N-Oxides And Of Ester And Amide Derivatives Of 3-Hydroxy-2-Quinoxalinecarboxylic Acid By A Novel Process Consisting Of The Reaction Between A Benzofuroxan And An Activated Methylene-Containing Compound Under Basic Conditions.
合成参考文献
参考文献:10.1007/978-3-030-84961-0_11 摘要:Ahluwalia VK. Stereochemistry of Elimination Reactions. 2022. In: Stereochemistry of Organic Compounds. 参考文献:10.1007/s11746-997-0072-6 摘要:Saito H, Ishihara K. Antioxidant activity and active sites of phospholipids as antioxidants. J Americ Oil Chem Soc. 1997 Dec;74(12):1531–6. doi: 10.1007/s11746-997-0072-6. 参考文献:10.1007/s10570-024-05769-0 摘要:Park S, Rahmani F, Treasure T, Lee J, Tiller P, Pasquinelli MA, Kelley SS, Park S. Understanding the formation of insoluble gel particles during cellulose diacetate production. Cellulose. 2024 Feb 17;31(4):2141–50. doi: 10.1007/s10570-024-05769-0. 参考文献:10.1007/978-3-031-61095-0_10 摘要:Bamsaoud SF, Wahoud ARY, Rana A, Abdul-Majeed AM, Bin-Hameed EA. Smart Biosensors for Environment Sustainability. 2024. In: Advances in Plant Breeding Strategies. 参考文献:10.1007/s11244-025-02169-x 摘要:Yao P, Zhang J, Li E, Wang Y, Cheng R. Experimental and Theoretical Studies on Extractive Desulfurization of Thiophene Sulfides in Fuel Oil by Triethylenediamine-Based Ionic Liquids. Top Catal. 2025 Oct 07;(). doi: 10.1007/s11244-025-02169-x.