CAS: 21236-97-5; 6-Amino-3-Methylpyrimidine-2,4(1H,3H)-Dione

相似化合物

6642-31-5 1142201-78-2 2434-53-9

上下游产品

CAS号873-83-6 6-氨基尿嘧啶 | CAS号74-88-4 碘甲烷 | CAS号54030-56-7 6-氨基-2-甲基硫代-3-甲基尿嘧啶 | CAS号138895-26-8 N-trimethylsily... | CAS号94940-32-6 6-Amino-2-metho... | CAS号110472-85-0 Ethyl 3-amino-3... | CAS号372-09-8 氰基乙酸 | CAS号598-50-5 甲基脲 | CAS号19893-78-8 5-乙酰氨基-6-氨基-3-甲... | CAS号6136-37-4 3,7-二氢-1-甲基-1H-... | CAS号61033-04-3 6-氨基-5-亚硝基-3-甲基尿嘧啶 | CAS号53727-29-0 1-甲基-3-苯基嘧啶-2,4,6-三酮 | CAS号50996-15-1 Formamide,N-(4-... | CAS号40959-24-8 5,6-二氨基-3-甲基尿嘧啶,半水合物

6-氨基-2-甲氧基-3-甲基-4(3H)-嘧啶酮置于盐酸体系中,化学反应生成6-氨基-3-甲基尿嘧啶
参考文献:Pfleiderer,Chemische Berichte,1957,Vol. 90,P. 2272,2275
标题:Pfleiderer,Chemische Berichte,1957,Vol. 90,P. 2272,2275

专利信息

专利号:US-2023010886-A1
优先权日:2019-09-23
标 题 :Shp2 inhibitors and uses thereof
发明人：XIE YINONG; BABISS LEE E
权利人:SUZHOU PUHE BIOPHARMA CO LTD
摘要:Compounds of Formula 1 as inhibitors of protein tyrosine phosphatase SHP2 are disclosed. The pharmaceutical compositions comprising compounds of Formula 1, methods of synthesis of these compounds, methods of treatment for diseases associated with the aberrant activity of SHP2 such as cancer using these compounds or compositions containing these compounds are also disclosed.

专利号:US-10561655-B2
优先权日:2018-03-21
标 题 :SHP2 inhibitors and uses thereof
发明人：XIE YINONG; BABISS LEE E
权利人:SYNBLIA THERAPEUTICS INC
摘要:Compounds of Formula 1 as inhibitors of protein tyrosine phosphatase SHP2 are disclosed. The pharmaceutical compositions comprising compounds of Formula 1, methods of synthesis of these compounds, methods of treatment for diseases associated with the aberrant activity of SHP2 such as cancer using these compounds or compositions containing these compounds are also disclosed.

专利号:WO-2025067239-A1
优先权日:2023-09-26
标 题 :Kinesin kif18a inhibitor, and application thereof
发明人：XIAO YISONG; GU XIAOHUI; LAI KUNMIN; WANG MINGHUA; HU MIN
权利人:SHANGHAI APEIRON THERAPEUTICS COMPANY LTD
摘要:A KIF18 inhibitor, and a synthesis method therefor, capable of adjusting a KIF18A protein, so as to affect cell cycle and cell proliferation processes, in order to treat cancers and cancer-related diseases. Also provided are a pharmaceutical composition including the KIF18 inhibitor compound, and a method for treating KIF18A activity-related conditions.

专利号:US-12233062-B2
优先权日:2018-09-26
标 题 :Heterocyclic derivatives useful as SHP2 inhibitors
发明人：HAN HUIFENG; GAO PANLIANG; MA CUNBO; KANG DI
权利人:JACOBIO PHARMACEUTICALS CO LTD
摘要:This invention provides a compound of formula I, their synthesis and their use for treating a SHP2 mediated disorder. More particularly, this invention provides a pharmaceutical composition comprising the said compound.