CAS: 1068-21-9; Diethylphosphoramidate

相似化合物

85232-02-6 34008-16-7 720707-93-7

上下游产品

CAS号814-49-3 氯磷酸二乙酯 | CAS号762-04-9 亚磷酸二乙酯 | CAS号22749-09-3 diethoxy-trimet... | CAS号1516-68-3 diethyl azido p... | CAS号29668-61-9 (1-氰基乙基)膦酸二乙酯 | CAS号464-06-2 2,2,3-三甲基丁烷 | CAS号126-68-1 O,O',O''-硫代磷酸三乙酯 | CAS号79-29-8 2,3-二甲基丁烷 | CAS号6185-96-2 dichloromethyle... | CAS号6415-20-9 Diisopropyl pho... | CAS号22749-09-3 diethoxy-trimet... | CAS号598-02-7 磷酸二乙酯 | CAS号20039-33-2 二乙氧基异氰酸膦酯 | CAS号32405-88-2 环己酰胺基磷酸二乙酯 | CAS号16626-93-0 (diethoxyphosph... | CAS号65088-78-0 Phosphoramidic ... | CAS号4921-73-7 1-[ethoxy-(sulf... | CAS号55595-96-5 N,1-bis(diethox...

📜特普置于氨,Sodium Amide体系中,化学反应生成氨基磷酸二乙酯
参考文献:Klement,R.; Wild,A.,Chemische Berichte,1963,Vol. 96,P. 1916-1926
标题:Klement,R.; Wild,A.,Chemische Berichte,1963,Vol. 96,P. 1916-1926

专利信息

专利号:US-11325912-B2
优先权日:2019-05-09
标题 :Regio-selective synthesis of imidazo[1,2-a]pyrimidines
发明人：CLAGG KYLE BRADLEY PASCUAL; WHITE NICHOLAS ANDREW; ZHANG HAIMING; GOSSELIN FRANCIS; NACK WILLIAM; O'SHEA PAUL D
权利人:GENENTECH INC
摘要:A method of regio-selectively synthesizing an imidazo-pyrimidine compound of formulae (XXa) or (XXb)comprising a step of coupling a first compound of formula XX-P1a or XX-P1b with a second compound of formula XX-P2This annulation reaction between β-ethoxy acrylamides and phosphorylated aminoimidazoles to furnish imidazo[1,2-a]pyrimidin-amines relies on steering effects from endocyclic and exocyclic phosphorylated aminoimidazoles. The reaction furnishes either 2-amino or 4-amino constitutional isomers of imidazo[1,2-a]pyrimidines with good yields and ranges of 90:10-99:1 regio-selectivity. The reaction is useful in the synthesis of various tracer molecules used in the study of neurological conditions such as where R3 and R4 together with the imidazole ring atoms to which they are bonded form a phenyl ring and the products are substituted benzimidazopyrimidines. The reaction can be generalized to form imidazo[1,2-a]pyrimidines substituted at either of their 2- and 4-positions by alkoxy or thioalkyl groups.

专利号:US-2007264694-A1
优先权日:2006-04-07
标题 :Use of non-standard bases and proximity effects for gene assembly and conversion of non-standard bases to standard bases during dna synthesis
发明人：PRUDENT JAMES R
权利人:ERAGEN BIOSCIENCES INC
摘要:The present methods relate to generating nucleic acid molecules using non-natural nucleotides. In some methods, the nucleic acid molecules may be generated by hybridizing a plurality of oligonucleotides comprising one or more non-natural nucleotides and using a polymerase and/or a coupling agent to link the hybridized oligonucleotides. The methods also relate to the use of proximity effects to generate nucleic acid molecules using non-natural nucleotides. Furthermore, the methods relate to the use of at least one non-natural base in a DNA template in order to generate a replicate of the DNA template in which the non-natural base has been replaced with a natural base.

专利号:WO-2012107537-A1
优先权日:2011-02-09
标题:Method for the detection of polynucleotide sequences
发明人：ROHAYEM JACQUES
权利人:RIBOXX GMBH; ROHAYEM JACQUES
摘要:The present invention relates to a method and kit for the detection of target polynucleotide sequences making use of terminal transferase and strand displacement techniques employing RNA-dependent RNA polymerases (RdRps) having duplex separation activity and being capable of de novo RNA synthesis in the absence of a primer on nucleic acid sequences.

专利号:WO-2019028391-A1
优先权日:2017-08-03
标 题 :DIALKYL PHOSPHONATE DIRECT METAL-FREE ARYLATION FOR THE SYNTHESIS OF MIXED ALKYL ARYLATED PHOSPHONATES

专利号:TW-I804079-B
优先权日:2019-05-09
标题 :Synthesis of labeled imidazo[1,2-a]pyrimidines

专利号:CN-114423763-A
优先权日:2019-05-09
标 题 :Regioselective synthesis of imidazo[1,2-a]pyrimidines