CAS: 80866-82-6; 5-Bromo-2-Methoxybenzyl Alcohol

• 英文名称5-Bromo-2-Methoxybenzyl Alcohol
• 中文名称5-溴-2-甲氧基苯甲醇
• IUPAC名称(5-bromo-2-methoxyphenyl)methanol
• 其它别名4-溴-2-(羟甲基)苯甲醚; 5溴2甲氧基苄醇; 5-Bromo-2-Methoxybenzyl Alcohol
• CAS编号80866-82-6
• MFCD编号:MFCD00004630
• EINECS号:279-586-7
• 分子式:C8H9BrO2
• 分子量:217.06
• 产品CID: 1803600
• 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

• 相似结构搜索
• InChIKey: HAOOGRLZVQWDBY-UHFFFAOYSA-N
• InChI=1S/C8H9BrO2/c1-11-8-3-2-7(9)4-6(8)5-10/h2-4,10H,5H2,1H3…
• 计算化学: 氢键受体数2.0氢键供体数1.0可旋转键数2.0

物理性质

• 熔点68-71°C
• 沸点192.5 °C at 760 mmHg
• 闪点134.9±23.2 °C
• 密度1.5±0.1 g/cm3
• PSA:29.46
• LogP:1.95
• 折射率1.570
• 蒸汽压0.0±0.7 mmHg at 25°C
• 敏感性按规定使用和贮存的不会分解，避氧化物、酸、酸性氯化物，酸酐
• 外观形态白色至淡黄色粉末至晶体
• 储存条件密封, 常温干燥保存
• 产品应用该化合物用于合成5-溴-2-甲基苯乙酸.

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别急性毒性 类别4(吸入)
  急性毒性 类别4(经皮)
  急性毒性 类别4(经口)
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  严重眼刺激 类别2
• 警示词Warning(警告)
• 危险描述H332 |吸入有害.
  H312 |皮肤接触有害.
  H302 |吞咽有害.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
  H319 |造成严重眼刺激.
• 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
• UN编号NONH for all modes of transport
• 危险品标志Xn,Xi
• 风险等级Irritant
• 安全声明37/39-26-24/25
• 危险类别码36/37/38-22
• WGK Germany3

欧盟法规

上下游产品

合成工艺路线路线简述

• 25016-01-7 = 80866-82-6
  反应条件:1.1 Reagents: Sodium Borohydride Solvents: Methanol; 0 °C; 1 H,Rt1.2 Solvents: Water; 0 °C
  标题:Development Of Versatile Sulfone Electrophiles For Suzuki-Miyaura Cross-Coupling Reactions
  作者:Nambo,Masakazu; Et Al
  参考文献:Acs Catalysis 日期:2017 卷标:7(2) 页码:1108-1112]
  
  = 80866-82-6
  反应条件:1.1 Reagents: Lithium Aluminum Hydride Solvents: Tetrahydrofuran; 0 °C; 12 H,Rt1.2 Reagents: Water; Rt
  标题:Room-Temperature Ortho-Alkoxylation And -Halogenation Of N-Tosylbenzamides By Using Palladium(Ii)-Catalyzed C-H Activation
  作者:Peron,Florent; Et Al
  参考文献:Chemistry - A European Journal 日期:2014 卷标:20(24) 页码:7507-7513]
  
  = 80866-82-6
  反应条件:1.1 Reagents: Triethylamine,Sodium Hydroxide Solvents: Chloroform; 55 - 60 °C2.1 Reagents: Sodium Hydroxide Solvents: Water; Rt3.1 Reagents: Sodium Borohydride Solvents: Methanol; Rt
  标题:First Total Synthesis Of 12-Hydroxy-13-Methylpodocarpa-9,11,13-Trien-3-One
  作者:Zhang,Cheng Lu; Et Al
  参考文献:Chinese Chemical Letters 日期:2006 卷标:17(2) 页码:163-164]
  
  = 80866-82-6
  反应条件:1.1 Reagents: Trifluoroacetic Acid,Chlorosuccinimide Catalysts: Palladium Diacetate Solvents: Methanol; 13 H,25 °C2.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; 3 H,Rt3.1 Reagents: Lithium Aluminum Hydride Solvents: Tetrahydrofuran; 0 °C; 12 H,Rt3.2 Reagents: Water; Rt
  标题:Room-Temperature Ortho-Alkoxylation And -Halogenation Of N-Tosylbenzamides By Using Palladium(Ii)-Catalyzed C-H Activation
  作者:Peron,Florent; Et Al
  参考文献:Chemistry - A European Journal 日期:2014 卷标:20(24) 页码:7507-7513]
  
  612-16-8 = 80866-82-6 + 135-02-4
  反应条件:1.1 Reagents: N-Bromosuccinimide Solvents: 1,4-Dioxane,Water; 1 H,25 - 30 °C
  标题:N-Bromosuccinimide. A Facile Reagent For The Oxidation Of Benzylic Alcohols To Aldehydes
  作者:Adimurthy,Subbarayappa; Et Al
  参考文献:Synthetic Communications 日期:2007 卷标:37(9) 页码:1571-1577]
  
  25016-01-7 = 80866-82-6
  反应条件:1.1 Reagents: Sodium Borohydride Solvents: Methanol,Tetrahydrofuran; 10 Min,Rt; 3 H,Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Rt
  标题:3-[(5-Chloro-2-Hydroxyphenyl)Methyl]-5-[4-(Trifluoromethyl)Phenyl ]-1,3,4-Oxadiazol-2(3H)-One,Bms-191011: Opener Of Large-Conductance Ca2+-Activated Potassium (Maxi-K) Channels,Identification,Solubility,And Sar
  作者:Romine,Jeffrey L.; Et Al
  参考文献:Journal Of Medicinal Chemistry 日期:2007 卷标:50(3) 页码:528-542]
  
  612-16-8 = 80866-82-6
  反应条件:1.1 Reagents: Iodobenzene Diacetate,Lithium Bromide Solvents: 2,2,2-Trifluoroethanol; 10 Min,Rt
  标题:Dehydroxymethyl Bromination Of Alkoxybenzyl Alcohols By Using A Hypervalent Iodine Reagent And Lithium Bromide
  作者:Shibata,Ayako; Et Al
  参考文献:Synlett 日期:2018 卷标:29(17) 页码:2275-2278]
  
  612-16-8 = 80866-82-6
  反应条件:1.1 Reagents: Bromine(1+),Bis(2,4,6-Trimethylpyridine)-,Hexafluorophosphate(1-) (1:1) Solvents: Dichloromethane
  标题:Bis(Sym-Collidine)Bromine(I) Hexafluorophosphate As Oxidant
  作者:Rousseau,G.; Et Al
  参考文献:Tetrahedron Letters 日期:2000 卷标:41(46) 页码:8881-8885]
  
  612-16-8 = 80866-82-6
  反应条件:1.1 Reagents: N-Bromosuccinimide Solvents: 1,4-Dioxane,Water; 1 H,70 °C
  标题:N-Bromosuccinimide. A Facile Reagent For The Oxidation Of Benzylic Alcohols To Aldehydes
  作者:Adimurthy,Subbarayappa; Et Al
  参考文献:Synthetic Communications 日期:2007 卷标:37(9) 页码:1571-1577]
  
  = 80866-82-6
  反应条件:1.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; 3 H,Rt2.1 Reagents: Lithium Aluminum Hydride Solvents: Tetrahydrofuran; 0 °C; 12 H,Rt2.2 Reagents: Water; Rt
  标题:Room-Temperature Ortho-Alkoxylation And -Halogenation Of N-Tosylbenzamides By Using Palladium(Ii)-Catalyzed C-H Activation
  作者:Peron,Florent; Et Al
  参考文献:Chemistry - A European Journal 日期:2014 卷标:20(24) 页码:7507-7513]
  
  1761-61-1 = 80866-82-6
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water; Rt2.1 Reagents: Sodium Borohydride Solvents: Methanol; Rt
  标题:First Total Synthesis Of 12-Hydroxy-13-Methylpodocarpa-9,11,13-Trien-3-One
  作者:Zhang,Cheng Lu; Et Al
  参考文献:Chinese Chemical Letters 日期:2006 卷标:17(2) 页码:163-164]
  
  1711-09-7 + 70-55-3 = 80866-82-6
  反应条件:1.1 Reagents: Triethylamine Catalysts: 4-(Dimethylamino)Pyridine Solvents: Toluene,Ethyl Acetate; 15 Min,Rt; 1 H,55 °C; 55 °C -> Rt1.2 Reagents: Hydrochloric Acid Solvents: Water; Rt2.1 Reagents: Trifluoroacetic Acid,Chlorosuccinimide Catalysts: Palladium Diacetate Solvents: Methanol; 13 H,25 °C3.1 Reagents: Potassium Carbonate Solvents: Dimethylformamide; 3 H,Rt4.1 Reagents: Lithium Aluminum Hydride Solvents: Tetrahydrofuran; 0 °C; 12 H,Rt4.2 Reagents: Water; Rt
  标题:Room-Temperature Ortho-Alkoxylation And -Halogenation Of N-Tosylbenzamides By Using Palladium(Ii)-Catalyzed C-H Activation
  作者:Peron,Florent; Et Al
  参考文献:Chemistry - A European Journal 日期:2014 卷标:20(24) 页码:7507-7513]
  
  612-16-8 = 80866-82-6 + 25016-01-7
  反应条件:1.1 Reagents: Disodium Hydrogen Phosphate Dodecahydrate,1-Butanaminium,N,N,N-Tributyl-,Dichlorobromate(1-) (1:1) Solvents: Hexane,Water; 5 H,60 °C1.2 Reagents: Sodium Sulfite Solvents: Water; Rt
  标题:Oxidation Of Benzyl Alcohols With Tetraalkylammonium Dichlorobromate(1-)
  作者:Negoro,Tekeshi; Et Al
  参考文献:Wakayama Daigaku Kyoikugakubu Kiyo 日期:2003 卷标:53 页码:7-18

海关参考信息

• 2902300000-甲苯
  2905110000-甲醇
  2906210000-苄醇
  2907121100-间甲酚
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

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• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
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