CAS: 756520-78-2; (2-(Methylsulfonamido)Phenyl)Boronic Acid

上下游产品

CAS号5570-18-3 2-氨基苯硼酸 | CAS号124-63-0 甲基磺酰氯

2-氨基苯硼酸,甲基磺酰氯置于三乙胺体系中,用 二氯甲烷 作为反应溶剂,化学反应 2.0H,以16%的收率获得产物2-甲磺酰氨基苯硼酸
参考文献:Fused Heterotricyclic Compounds As Inhibitors Of 17Beta-Hydroxysteroid Dehydrogenase 3
标题:Fused Heterotricyclic Compounds As Inhibitors Of 17Beta-Hydroxysteroid Dehydrogenase 3
摘要:融合杂三环化合物,使用这种化合物治疗激素敏感性疾病如前列腺癌的方法,以及含有这种化合物的药物组合物.

专利信息

专利号:US-2007275968-A1
优先权日:2004-09-07
标 题 :Substituted Biphenyl Derivative
发明人：KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
权利人:KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
摘要:The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: n nwherein n R 1 represents a C 6 -C 10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C 1 -C 6 alkyl)amino group, a di-(C 1 -C 6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C 1 -C 6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R 2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R 3 represents a C 1 -C 6 alkyl group, and so on; and R 4 represents a C 1 -C 6 alkyl group, and so on.