CAS: 546-62-3; (2R,3R,4S,5S,6R)-2-(((2S,3S,4S,5R)-3,4-Dihydroxy-2,5-Bis(Hydroxymethyl)Tetrahydrofuran-2-yl)Oxy)-6-((((2S,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-((((2S,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-((((2S,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Methyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Methyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Methyl)Tetrahydro-2H-Pyran-3,4,5-Triol

上下游产品

D-raffinose

📜在 Palladium On Activated Charcoal,氢气体系中,用 甲醇,乙酸乙酯 作为反应溶剂,化学反应 48.0H,以11 Mg的收率获得产物毛蕊花糖
参考文献:Co 2(co)8 / Et 3 Sih / Co系统的区域选择性脱-O-苄化反应合成棉子糖家族寡糖
标题:Co 2(co)8 / Et 3 Sih / Co系统的区域选择性脱-O-苄化反应合成棉子糖家族寡糖
摘要:提出了一种方便的方法,以蔗糖为原料合成棉子糖,水苏糖和马齿c糖.关键步骤是使用co 2(co)8 / Et 3 Sih / Co系统进行区域选择性脱o-苄基化,然后进行高水平的α-选择性糖基化.新开发的脱-O-苄基化系统可在温和条件下以高选择性高效去除蔗糖和棉子糖的伯苄基.使用硫代糖苷作为供体,Nis / Agotf作为启动子,Dtbmp作为添加剂,酸不稳定蔗糖底物的糖基化可以实现高收率.
DOI:10.1016/j.Tet.2013.03.094

专利信息

专利号:US-2004128713-A1
优先权日:1997-04-08
标题 :Soybean plant producing seeds with reduced levels of raffinose saccharides and phytic acid
发明人：HITZ WILLIAM D; SEBASTIAN SCOTT ANTHONY; GRACE DORMAN JOHN; STREIT LEON GEORGE
摘要:A soybean enzyme, myo-inositol 1-phosphate synthase, whose manipulation results in the alteration of raffinose saccharide, sucrose, phytic acid and inorganic phosphate content of soybean seeds, thus leading to valuable and useful soybean products, has been identifed. Soybean lines with decreased capacity for the synthesis of myo-inositol 1-phosphate in the tissue of developing seeds in comparison to seeds of other soybean lines, have been developed. As taught herein, reduction of myo-inositol 1-phosphate synthase enzymatic activity by any of several means will result in soybean seeds displaying this desirable phenotype.

专利号:US-2002064816-A1
优先权日:1999-12-16
标 题 :Moss genes from physcomitrella patens encoding proteins involved in the synthesis of carbohydrates
发明人：LERCHL JENS; RENZ ANDREAS; EHRHARDT THOMAS; REINDL ANDREAS; CIRPUS PETRA; BISCHOFF FRIEDRICH; FRANK MARKUS; FREUND ANNETTE; DUWENIG ELKE; SCHMIDT RALF-MICHAEL; RESKI RALF
摘要:Isolated nucleic acid molecules, designated CMRP nucleic acid molecules, which encode novel CMRPs from Physcomitrella patens are described. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing CMRP nucleic acid molecules, and host cells and organisms into which the expression vectors have been introduced. The invention still further provides isolated CMRPs, mutated CMRPs, fusion proteins, antigenic peptides and methods for the improvement of production of a desired compound from transformed cells based on genetic engineering of CMRP genes in this organism.

专利号:WO-2024107474-A1
优先权日:2022-11-15
标 题 :Controlled lipid self-assembly for scalable manufacturing of next-generation immune stimulating complexes
发明人：IRVINE DARRELL; HAMMOND PAULA; PIRES IVAN SUSIN
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:Methods of controlled lipid self-assembly for scalable manufacturing of next-generation immune stimulating complexes (ISCOMs) are described. The methods involve mixing one or more saponins, one or more lipids, one or more sterols, one or more additional adjuvants (e.g., TLR4 agonist), and optionally one or more antigens in the presence of a detergent. Typically, the mixing step is followed by an incubation step, a dilution and/or concentration step, and/or a filtration or dialysis step for removing detergent. Preferably, methods involve a tangential flow filtration (TFF) process suitable for scalable synthesis and Good Manufacturing Practice (GMP) production of highly homogeneous clinical-grade ISCOM-based adjuvants.

专利号:US-2011296543-A1
优先权日:2006-06-01
标题:Nucleic acids and proteins and methods for making and using them
发明人：CHANG HWAI; MATHUR ERIC J; CAYOUETTE MICHELLE; ROBERTSON DAN E; HUGENHOLTZ PHILIP; WARNECKE FALK; LEADBETTER JARED R; IVANOVA NATALIA; LUGINBUHL PETER; HUTCHISON DON
权利人:CHANG HWAI; MATHUR ERIC J; CAYOUETTE MICHELLE; ROBERTSON DAN E; HUGENHOLTZ PHILIP; WARNECKE FALK; LEADBETTER JARED R; IVANOVA NATALIA; LUGINBUHL PETER; HUTCHISON DON; UNIV CALIFORNIA; CALIFORNIA INST OF TECHN; VERENIUM CORP
摘要:The invention provides polypeptides, including enzymes, structural proteins and binding proteins, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. Polypeptides, including enzymes and antibodies, and nucleic acids of the invention can be used in industrial, experimental, food and feed processing, nutritional and pharmaceutical applications, e.g., for food and feed supplements, colorants, neutraceuticals, cosmetic and pharmaceutical needs. Polypeptides of the invention can be used in food processing, brewing, bath additives, alcohol production, peptide synthesis, enantioselectivity, hide preparation in the leather industry, waste management and animal degradation, silver recovery in the photographic industry, medical treatment, silk degumming, biofilm degradation, biomass conversion to a biofuel (e.g., a bioethanol, biomethanol, biopropanol or biobutanol, a biodiesel, etc.), biodefense, antimicrobial agents and disinfectants, personal care and cosmetics, biotech reagents, in corn wet milling and pharmaceuticals such as digestive aids and anti-inflammatory (anti-phlogistic) agents.

专利号:CN-119351239-B
优先权日:2024-12-26
标题:Recombinant pichia pastoris and application thereof in synthesis of stachyose and verbascose

专利号:CN-119351239-A
优先权日:2024-12-26
标题 :Recombinant pichia pastoris and application thereof in synthesis of stachyose and verbascose