CAS: 52565-56-7; 4-Phenylpicolinic Acid

该化合物是一种环环的混合有机化合物,在2位置上有一个附于环状环的苯基组,在2位置上有一个箱状酸功能组.这种结构使它在制药和农用化学合成中具有多种用途的中间体,特别是在开发活性成分和精细化学品方面.它的芳香和盒状功能允许进一步衍生,使在离心设计,协调化学和药用化学研究中的应用成为可能.该化合物在标准条件下具有良好的稳定性,便于处理和储存.其定义明确的再活动特征使它成为在学术和工业环境中建造复杂的分子结构的宝贵建筑.

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CAS号98-80-6 苯硼酸

合成工艺路线路线简述

    📜2-溴-4-苯基吡啶置于四(三苯基膦)钯,乙醇,Sodium Hydroxide体系中,用 N,N-二甲基乙酰胺 作为反应溶剂,化学反应生成 4-苯基吡啶-2-羧酸
    参考文献:Wo2019231942A5
    标题:Wo2019231942A5

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    专利信息


    专利号:EP-3515880-B1
    优先权日:2017-03-17
    标题:Methods and compositions for synthesis of encoded libraries
    发明人:LI JIN; MORGAN BARRY A; Wan jinqiao; DOU DENGFENG; LIU GUANSAI; CHANG YONG; CHEN QIUXIA; WANG XING; XU YANSHAN; HU DONGYAN; LIU JIAN; CHENG XUEMIN
    权利人:HITGEN INC

    专利号:US-2020149034-A1
    优先权日:2017-03-17
    标题:Methods and Compositions for Synthesis of Encoded Libraries

    专利号:WO-2006079916-A1
    优先权日:2005-01-26
    标 题 :Thieno [2,3-d] pyrimidine compounds as inhibitors of adp-mediated platelets aggregation
    发明人:ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; RAHMAN HAYAT; SCHWEITZER BARBARA ANN; TENBRINK RUTH ELIZABETH
    权利人:PHARMACIA & UPJOHN CO LLC; ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; RAHMAN HAYAT; SCHWEITZER BARBARA ANN; TENBRINK RUTH ELIZABETH
    摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I): wherein A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

    专利号:US-7199105-B2
    优先权日:2002-08-15
    标 题:Lincomycin derivatives possessing antibacterial activity
    发明人:LEWIS JASON G; PATEL DINESH V; ANANDAN SAMPATH KUMAR; GORDEEV MIKHAIL F
    权利人:VICURON PHARM INC
    摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

    专利号:US-7164011-B2
    优先权日:2002-08-15
    标题:Lincomycin derivatives possessing antibacterial activity
    发明人:LEWIS JASON; PATEL DINESH V; ANANDAN SAMPATH K; GORDEEV MIKHAIL F
    权利人:VICURON PHARM INC
    摘要:Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

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    合成参考文献


    参考文献:10.1007/978-981-19-0832-3_1
    摘要:Rajbongshi KK, Dam B, Patel BK. Pyridines, Dihydropyridines and Piperidines: An Outline on Synthesis and Biological Activities. 2022. In: N-Heterocycles.
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