CAS: 41044-12-6; 7-(Diethylamino)-3-(1-Methyl-1H-Benzo[d]Imidazol-2-yl)-2H-Chromen-2-One

该化合物是科马林家族的荧光染色,以其在绿黄地区大量排放而闻名(~500-550纳米) . 它具有高量产量和可光度,适合激光染料,荧光探针和光电子装置的应用. 化合物在有机溶剂中的溶解性及其与聚合物基体的兼容性增强了其在材料科学中的效用. 科马林 30 也因其敏锐吸收和排放特征而受到重视,从而得以进行精确的光谱研究. 它在不同pH条件下的稳定性进一步扩大了其在生物化学和环境感学中的可应用性. 这些特性使得它成为需要始终保持荧光作用的研究和工业应用的可靠选择.

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上下游产品

7-diethylamin°Coumarine-3-aldehyde N-methyl-1,2-phenylenediamine 4-(Diethylamino)salicylaldehyde 7-diethylamino-2H-benzopyran-2-one

合成工艺路线路线简述

    📜香豆素 110置于sodium Hydrogensulfite,三氯氧磷体系中,用 甲醇 作为反应溶剂,化学反应 7.5H,反应生成 香豆素 30
    参考文献:香豆素-30及其异构体7-(二乙氨基)-4-(1-甲基-1H-苯并咪唑-2-基)香豆素的简明合成及荧光性质
    标题:香豆素-30及其异构体7-(二乙氨基)-4-(1-甲基-1H-苯并咪唑-2-基)香豆素的简明合成及荧光性质
    摘要:Coumarin-30 及其区域异构体 7-(Diethylamino)-4-(1-Methyl-1H-Benzimidazol-2-yl)Coumarin 以相应的甲酰基香豆素与 N-Methylphenylene-1,2-Diamine 的缩合为关键步骤合成. 此外,记录了两种香豆素的吸收和荧光发射光谱.
    DOI:10.3184/174751916X14738553653270

    海关参考信息

    专利信息


    专利号:US-12006540-B2
    优先权日:2015-09-28
    标题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis
    发明人：JU JINGYUE; LI XIAOXU; CHEN XIN; LI ZENGMIN; KUMAR SHIV; SHI SHUNDI; GUO CHENG; REN JIANYI; HSIEH MIN-KANG; CHIEN MINCHEN; TAO CHUANJUAN; ERTURK ECE; KALACHIKOV SERGEY; RUSSO JAMES J
    权利人:UNIV COLUMBIA
    摘要:Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.

    专利号:US-11959137-B2
    优先权日:2015-09-28
    标题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis

    专利号:US-2024376536-A1
    优先权日:2015-09-28
    标题 :Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis

    专利号:US-2022411860-A1
    优先权日:2015-09-28
    标题:Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis

    专利号:US-2023160000-A1
    优先权日:2015-09-28
    标 题:Synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis

    专利号:US-2023028388-A1
    优先权日:2015-09-28
    标 题 :Design and synthesis of novel disulfide linker based nucleotides as reversible terminators for dna sequencing by synthesis

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    合成参考文献


    摘要:L808: ATSDR - Agency for Toxic Substances and Disease Registry (1990). Toxicological profile for silver. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
    参考文献:10.1021/jm701302v
    摘要:Auld DS, Southall NT, Jadhav A, Johnson RL, Diller DJ, Simeonov A, Austin CP, Inglese J. Characterization of chemical libraries for luciferase inhibitory activity. J Med Chem. 2008 Apr 24;51(8):2372–86. doi: 10.1021/jm701302v.
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