专利号:US-9217012-B2 优先权日:2009-04-08 标题 :Inhibitors of protein tyrosine phosphatases 发明人:ZHANG ZHONG-YIN; ZHANG SHENG 权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP 摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.
参考文献:10.1007/s12374-024-09428-6 摘要:Zhou S, Zi X, Rao D, Liu K, Yang L, Shen P, Wu B, Zhou F. Jasmonic Acid Mediates Maize (Zea mays L.) Roots Response to Soil Nitrogen Heterogeneity. J. Plant Biol. 2024 May 06;67(3):241–55. doi: 10.1007/s12374-024-09428-6. 参考文献:10.1007/s11104-026-08368-z 摘要:Del Vecchio G, Salehi H, Ardenti F, Castro-Cegri A, Fiorini A, Lucini L. Distinctive and synergistic effects of an Ascophyllum nodosum extract and a nitrification inhibitor on tomato growth, photosynthetic efficiency, and metabolomic profile under low nitrogen conditions. Plant Soil. 2026 Feb 13;520(2):1815–31. doi: 10.1007/s11104-026-08368-z.