CAS: 20501-56-8; (3S,6S,6Ar,7R,7Ar,8S,9S,10S,11As,12S,12Ar,14R)-1-Ethyl-6,10-Dimethoxy-3-(Methoxymethyl)Tetradecahydro-11Ah-3,6A,12-(Epiethane[1,1,2]Triyl)-7,9-Methanonaphtho[2,3-B]Azocine-8,11A-Diol
该化合物是一种属于alkaloid类的化学化合物,该类物质是自然产生的有机化合物,主要含有基本氮原子,该物质来自各种植物来源,以其潜在的药理特性而著称.Talatisamine呈现出一种复杂的分子结构,有助于其生物活动.已经研究过它对...
- 英文名称(3S,6S,6Ar,7R,7Ar,8S,9S,10S,11As,12S,12Ar,14R)-1-Ethyl-6,10-Dimethoxy-3-(Methoxymethyl)Tetradecahydro-11Ah-3,6A,12-(Epiethane[1,1,2]Triyl)-7,9-Methanonaphtho[2,3-B]Azocine-8,11A-Diol
- 中文名称塔拉萨敏
- IUPAC名称(3S,6S,6aR,7R,7aR,8S,9S,10S,11aS,12S,12aR,14R)-1-ethyl-6,10-dimethoxy-3-(methoxymethyl)tetradecahydro-11aH-3,6a,12-(epiethane[1,1,2]triyl)-7,9-methanonaphtho[2,3-b]azocine-8,11a-diol
- 其它别名20-Ethyl-1α,16β-Dimethoxy-4-(Methoxymethyl)Aconitane-8,14α-Diol; Talatizamine; Talatisaminea; Aconitane-8,14-Diol, 20-Ethyl-1,16-Dimethoxy-4-(Methoxymethyl)-, (1α,14α,16β)-; Alatisamine; (3S,6S,6Ar,7R,7Ar,8S,9S,10S,11As,12S,12Ar,14R)-1-Ethyl-6,10-Dimethoxy-3-(Methoxymethyl)Tetradecahydro-11Ah-3,6A,12-(Epiethane[1,1,2]Triyl)-7,9-Methanonaphtho[2,3-B]Azocine-8,11A-Diol; Kcsa,Inhibitor,Alzheimer'S,Talatisamine,Neurotoxicity,Inhibit,Potassium Channel,Disease
- CAS编号20501-56-8
- MFCD编号:MFCD00221750
- 分子式:C24H39NO5分子量:421.58
- 产品CID: 1039214
- 产品分类天然产物 → 生物碱
物理性质
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主要参考文献
1: Zhou Q, Ma J, Liu Q, Wu C, Yang Z, Yang T, Chen Q, Yue Y, Shang J. Traditional Chinese Medicine formula, Sanwujiao granule, attenuates ischemic stroke by promoting angiogenesis through early administration. J Ethnopharmacol. 2024 Mar 1;321:117418. doi: 10.1016/j.jep.2023.117418. Epub 2023 Nov 17.
117:154907. doi: 10.1016/j.phymed.2023.154907. Epub 2023 May 29. 89(6):674-682. doi: 10.1055/a-1956-7542. Epub 2022 Oct 6. 38(1):85-90. doi: 10.1080/14786419.2022.2104276. Epub 2022 Aug 1. 46(17):4424-4432. Chinese. doi: 10.19540/j.cnki.cjcmm.20210622.201. 7(8):1311-1316. doi: 10.1021/acscentsci.1c00540. Epub 2021 Jul 27.
7: Xu X, Xie X, Zhang H, Wang P, Li G, Chen J, Chen G, Cao X, Xiong L, Peng F, Peng C. Water-soluble alkaloids extracted from Aconiti Radix lateralis praeparata protect against chronic heart failure in rats via a calcium signaling pathway. Biomed Pharmacother. 2021 Mar;135:111184. doi: 10.1016/j.biopha.2020.111184. Epub 2021 Jan 5.
合成参考文献
参考文献:10.1248/cpb.54.779
摘要:Cai L, Chen DL, Liu SY, Wang FP. New C19-diterpenoid alkaloids from Aconitum piepunense. Chem Pharm Bull (Tokyo). 2006 Jun;54(6):779–81. doi: 10.1248/cpb.54.779.
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