CAS: 202842-98-6; 3,4-Dimethyl-1H-Pyrazole Phosphate

相似化合物

2820-37-3 131661-41-1 112758-40-4

3,4-二甲基-1H-吡唑置于磷酸体系中,用 甲醇 用作溶剂,化学反应 2.0H,以75%的收率获得3,4-二甲基-1H-吡唑二氢磷酸盐
参考文献:一种3,4-二甲基吡唑及其磷酸盐的制备方法
标题:一种3,4-二甲基吡唑及其磷酸盐的制备方法
摘要:本发明公开了一种3,4‑二甲基吡唑及其磷酸盐的制备方法,包括如下步骤:S1,在反应溶剂中,采用碱性物质保持碱性条件下,2‑丁酮与甲酸酯于‑10‑50oc温度条件下进行反应,反应完成并经萃取分离后加入烷基化试剂继续反应,经后处理制得烯醚化合物的溶液;S2,将经步骤s1制得的烯醚化合物与水合肼或肼盐,在调节ph值至2‑9后于‑10‑60oc温度条件下进行反应,反应完成后加入所述碱性物质调节ph值至7‑11,经后处理后制得3,4‑二甲基吡唑.本发明的制备方法具有原料廉价,操作简便,收率高,三废处置简单,产品质量高,溶剂可实现回收套用等显著优点,并且适合工业化生产.

专利信息

专利号:US-2024123076-A1
优先权日:2021-02-08
标题:Unsaturated dendrimers compositions, related formulations, and methods of use thereof
发明人：LEE SANG M; SIEGWART DANIEL J
权利人:UNIV TEXAS
摘要:Described herein are novel lipid compositions comprising unsaturated dendrimers and methods of synthesis of unsaturated dendrimers. The lipid composition can comprise an ionizable cationic lipid, a phospholipid, and a selective organ targeting lipid. Also described herein are pharmaceutical formulations comprising an unsaturated dendrimer, a lipid composition, and a therapeutic agent. Further described in here are methods of mRNA delivery comprising a lipid composition and a therapeutic agent. Further described herein are high-potency dosage forms of a therapeutic formulated with a lipid composition.

专利号:US-2022127649-A1
优先权日:2019-01-30
标题:Engineered cells for improved production of cannabinoids
发明人：NOBLE MICHAEL A; MOORE JONATHAN; LI JINGYI; LECHNER ANNA
权利人:GENOMATICA INC
摘要:The invention provides non-natural microbial organisms containing enzymatic pathways and/or metabolic modifications for enhancing synthesis of olivetolic acid, olivetolic acid derivatives and/or cannabinoids.

专利号:CN-114728960-B
优先权日:2019-11-14
标 题:Improved synthesis of KRAS G12C inhibitor compounds

专利号:EP-1940855-A4
优先权日:2005-10-18
标 题:DIARYL ALKYLPHOSPHONATES AND THEIR METHODS OF SYNTHESIS

专利号:CN-109651571-A
优先权日:2018-12-28
标 题 :A kind of high impact ASA graft copolymer and synthesis method

专利号:CN-115073311-B
优先权日:2022-03-23
标题 :Efficient preparation of N, N ′ Synthesis method of-di (2-hydroxyethyl) aniline