CAS: 138797-71-4; (2R,3S)-2-((((9H-Fluoren-9-yl)Methoxy)Carbonyl)Amino)-3-(Tert-Butoxy)Butanoic Acid

上下游产品

(O-tert-butyl)-L-threonine 9-fluorenylmethyl N-succinimidyl carbonate N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide O-tert-Butyl-L-threonine Methyl Ester p-Toluenesulfonate

专利信息

专利号:US-8569452-B2
优先权日:2011-02-17
标题:Preparation of phalloidin and its derivatives
发明人：LIU BAOSHENG; ZHANG JIANHENG
权利人:LIU BAOSHENG; ZHANG JIANHENG; AMERICAN PEPTIDE COMPANY INC
摘要:The present invention relates to novel phalloidin derivatives and their fluorescent dye conjugates. These new compounds may be used in studies of actin dynamics in living systems. The present invention also relates to methods for preparing such compounds. The synthesis routes combine solid-phase and solution phase peptide synthesis, and has great advantage for efficient preparation of a diverse library of the phalloidin derivatives, especially for the synthesis of phalloidin.

专利号:US-11634741-B2
优先权日:2013-11-20
标 题:Synthesis of L-nucleic acids by means of an enzyme
发明人：PECH ANDREAS; JAROSCH FLORIAN; JAHNZ MICHAEL; KLUSSMANN SVEN; DAVID RALF
权利人:APTARION BIOTECH AG
摘要:The present invention is related to a method for adding one or more L-nucleotides to the 3′end of a first L-nucleic acid, wherein the method comprises the step of reacting the one or more L-nucleotides with the first L-nucleic acid in the presence of a protein comprising a mutant enzymatic activity exhibiting moiety, wherein the enzymatic activity is capable of adding one or more L-nucleotides to the 3′ end of the first L-nucleic acid, wherein the mutant enzymatic activity exhibiting moiety comprises an amino acid sequence, wherein the amino acids of the amino acid sequence are D-amino acids, wherein the mutant enzymatic activity exhibiting moiety is a variant of an enzymatic activity exhibiting moiety, wherein the enzymatic activity exhibiting moiety consists of an amino acid sequence according to SEQ ID NO: 15 and wherein the amino acids of the amino acid sequence according to SEQ ID NO: 15 are D-amino acids, wherein the amino acid sequence of the mutant enzymatic activity exhibiting moiety differs from the amino acid sequence of the enzymatic activity exhibiting moiety consisting of an amino acid sequence according to SEQ ID NO: 15 at least at one amino acid position, preferably at three amino acid positions, and/or wherein the amino acid sequence of the mutant enzymatic activity exhibiting moiety is a truncated form of an amino acid sequence according to SEQ ID NO: 15, and wherein the amino acid sequence of the mutant enzymatic activity exhibiting moiety is different from an amino acid sequence according to any of SEQ ID NOs 15 to 22 and 51.

专利号:US-2018208910-A1
优先权日:2012-05-16
标 题 :Enzymatic Synthesis of L-Nucleic Acids

专利号:EP-3071702-B1
优先权日:2013-11-20
标题 :Synthesis of l-nucleic acids by means of an enzyme

专利号:US-2016304926-A1
优先权日:2013-11-20
标题:Synthesis of L-Nucleic Acids by Means of an Enzyme

专利号:EP-2850192-B1
优先权日:2012-05-16
标 题 :Enzymatic synthesis of l-nucleic acids