CAS: 97-14-3; 2-Acetamido-3-Hydroxypropanoic Acid

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CAS号56-45-1 L-丝氨酸 | CAS号108-24-7 乙酸酐 | CAS号55299-56-4 N-Acetyl-DL-ser... | CAS号4985-36-8 Serine, acetate... | CAS号302-84-1 DL-丝氨酸 | CAS号302-84-1 DL-丝氨酸 | CAS号56-45-1 L-丝氨酸 | CAS号152612-69-6 N-乙酰基-D-丝氨酸 | CAS号23115-42-6 ethyl 2-acetami... | CAS号73491-58-4 2-acetamido-N-m... | CAS号4985-36-8 Serine, acetate...

📜N-Acetyl Serine Methyl Ester置于水,Lithium Hydroxide体系中,用 甲醇 作为反应溶剂,化学反应 0.5H,反应生成 N-乙酰基-Dl-丝氨酸
参考文献:Siloxyl Ether Functionalized Resins For Chemoselective Enrichment Of Carboxylic Acids
标题:Siloxyl Ether Functionalized Resins For Chemoselective Enrichment Of Carboxylic Acids
摘要:Although The Carboxylic Acid Moiety Is Prevalent In Many Biologically Produced Molecules,Including Natural Products And Proteins,Methods To Chemoselectively Target This Functional Group Have Remained Elusive. Generally,Strategies That Utilize Carboxylate Nucleophilicity Also Promote Reactions With Other Nucleophiles Such As Amines And Hydroxyls. A Reagent Was Sought To Facilitate The Selective Isolation Of Carboxylic Acid Containing Compounds From Complex Mixtures. Here,The Development Of Siloxyl Ether Functionalized Solid Supports Is Described.
DOI:10.1021/ol202376M

专利信息

专利号:US-2004175710-A1
优先权日:2001-05-22
标题:Method for in situ, on-chip chemical synthesis
发明人：HAUSHALTER ROBERT C
摘要:Apparatus and methods for the synthesis of arrays of molecules bound to a substrate, and in particular oligomeric molecules such as DNA oligonucleotides and peptides. The methods of the invention comprise providing a substrate having first and second surfaces and a plurality of isolated porous regions extending through the substrate and communicating with the first and second surfaces, contacting selected ones of the porous regions with a reagent, allowing the reagent to bind to or otherwise interact with the selected porous regions, and withdrawing unreacted first reagent from the substrate through the selected porous regions by introducing a pressure differential across the substrate. The events may be repeated as required to form oligomeric molecules.

专利号:US-5919523-A
优先权日:1995-04-27
标题:Derivatization of solid supports and methods for oligomer synthesis
发明人：SUNDBERG STEVEN A; JACOBS JEFFREY W; SCHULLEK JOHN R; MCGALL GLENN H; MIRZABEKOV ANDREI; TIMOFEEY EDWARD; FUJIMOTO DAVID; HOLMES CHRISTOPHER P; YANG HUA
权利人:AFFYMETRIX INC
摘要:Methods and derivatized supports which are useful in solid-phase synthesis of peptides, oligonucleotides or other small organic molecules as well as arrays of ligands. The methods provide means to control the functional site density on a solid support. Some of the derivatized supports are polymer-coated or glycan-coated. Other methods for regenerating the surface of a used ligand array are also provided.

专利号:US-8580542-B2
优先权日:2011-02-10
标 题 :Methods and compositions for producing alkenes of various chain length
发明人：RIDLEY CHRISTIAN P
权利人:RIDLEY CHRISTIAN P; JOULE UNLTD TECHNOLOGIES INC
摘要:The NonA alkene synthase in Synechococcus sp. displays selective synthesis of 1-nonadecene. Heterologous recombination of a domain, i.e. the acyl binding domain, with other acyl binding proteins, affects acyl substrate chain-length binding selectivity and therefore the chain-length of the synthesized 1-alkenes. Compositions and methods are provided to selectively synthesize 1-alkenes of various chain lengths.

专利号:US-9528127-B2
优先权日:2013-01-25
标 题:Recombinant synthesis of medium chain-length alkanes
发明人：SKRALY FRANK ANTHONY; LI NING
权利人:JOULE UNLIMITED TECH INC; JOULE UNILIMITED TECH INC
摘要:The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently produce alkanes, and in particular the use of such organisms for the commercial production of alkanes and related molecules. Other materials, methods, and compositions are also described.

专利号:US-5783674-A
优先权日:1989-02-17
标 题 :Method for the use and synthesis of peptides
发明人：GEYSEN HENDRIK MARIO
权利人:CHIRON CORP
摘要:A method for the separation of at least one specific binding entity from a mixture of binding entities by the steps of contacting a mixture of binding entities with immobilized peptides in which the peptides specifically bind to the specific binding entities and the peptides contain an amino acid which facilitates removal of the binding entities from the peptides, and separating the immobilized peptide/specific binding entity complexes from the mixture of binding entities. A change in incubation conditions facilitates removal of the binding entities from the immobilized peptides.

专利号:WO-9901561-A1
优先权日:1997-07-03
标题 :IMPROVED PROCESS FOR THE PRODUCTION OF β-LACTAMS
发明人：OSTERGAARD SIMON; NIELSEN JENS; VAN DEN BERG MARCO ALEXANDER
权利人:GIST BROCADES BV; OSTERGAARD SIMON; NIELSEN JENS; DEN BERG MARCO ALEXANDER VAN
摘要:The present invention discloses an enzyme obtainable from P. chrysogenum which is an O-acetyl-L-serine sulfhydrylase (OAS sulfhydrylase). It is shown for the first time that P. chrysogenum contains an enzyme activity associated with the direct sulfhydrylation pathway. The OAS sulfhydrylase of the invention is able to convert O-acetyl-L-serine (OAS) and sulphide into cysteine and acetate. The present invention thereby provides the possibility to increase the synthesis of L-cysteine via the direct sulfhydrylation pathway by e.g. genetic engineering of a β-lactam production organism, and, consequently, to improve the yield of β-lactams on glucose.