CAS: 5244-34-8; 2,2-(Ethane-1,2-Diylbis(Sulfanediyl))Diethanol

该化合物是一种含有硫磺的二醇,其特征是其独特的硫醚联系在静脉链中,该化合物主要因其作为有机合成的双功能构件的作用而受到重视,由于其对称结构而具有更大的灵活性和回活动性;硫磺原子的存在具有更好的铬化特性,使其在化学和聚合物应用的协调方面有用;其双氢氧基组能够直接发挥作用,便于将其纳入各种大型分子框架;此外,硫醚桥梁有助于提高热和化学稳定性,扩大其在材料科学中的用途;该二醇对于特殊聚合物,粘合物和交叉关联物剂的开发尤为重要.

结构式图片

相似化合物

7244-02-2 5271-38-5 24304-84-5

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号540-63-6 1,2-乙二硫醇 | CAS号107-07-3 2-氯乙醇 | CAS号106-93-4 1,2-二溴乙烷 | CAS号60-24-2 巯基乙醇 | CAS号75-08-1 乙硫醇 | CAS号75-21-8 环氧乙烷 | CAS号107-06-2 1,2-二氯乙烷 | CAS号3563-36-8 1,2-二乙烷 | CAS号64-17-5 乙醇 | CAS号3090-56-0 2-HYDROXYETHYLV... | CAS号505-29-3 1,4-二噻烷 | CAS号212078-35-8 3-quinolin-3-yl... | CAS号497-23-4 2(5H)-呋喃酮 | CAS号25423-55-6 2-[2-(2-sulfany... | CAS号19008-71-0 8-氨基-1-辛醇 | CAS号53293-00-8 5-己炔酸 | CAS号75039-84-8 反-2-十一烯醇 | CAS号3563-36-8 1,2-二乙烷 | CAS号1120-12-3 氨基壬酸 | CAS号7484-34-6 2,2'-(乙烷-1,2-二基...

合成工艺路线路线简述

    1,2-二乙烷置于水体系中,化学反应生成 3,6-二硫杂-1,8-辛二醇
    参考文献:Stein; Fruton; Bergmann,Journal Of Organic Chemistry,1946,Vol. 11,P. 703
    标题:Stein; Fruton; Bergmann,Journal Of Organic Chemistry,1946,Vol. 11,P. 703

    海关参考信息

    专利信息


    专利号:WO-2025125573-A1
    优先权日:2023-12-14
    标 题 :Manufacture of alpha, beta, gamma, delta or beta, gamma, delta di-unsaturated ketones carrying a terminal carboxyl group
    发明人:AQUINO FABRICE; BONRATH WERNER; GOETZINGER ALISSA; HAESS STEFAN; LEHMANN HAJO; MEDLOCK JONATHAN ALAN; PACE FRANCESCO; SORIANO DOMENICO; STEMMLER RENÉ TOBIAS
    权利人:DSM IP ASSETS BV
    摘要:The present invention relates to synthesis of carboxy group terminated di-unsaturated ketones having C=C double bonds at the α,β and γ,δ position or at the β,γ and γ,δ position relative to the carbonyl carbon atom. These ketones can be obtained easily and in few steps from respective alkynols having a terminal carboxyl group. These ketones are important key building block for the synthesis of derivatives of isoprenoids, especially of vitamin E.

    专利号:WO-2025125574-A1
    优先权日:2023-12-14
    标 题 :Manufacture of allylic alcohols carrying a terminal carboxyl group via ethynylation and lindlar hydrogenation
    发明人:AQUINO FABRICE; BONRATH WERNER; GOETZINGER ALISSA; HAESS STEFAN; LEHMANN HAJO; MEDLOCK JONATHAN ALAN; PACE FRANCESCO; SORIANO DOMENICO; STEMMLER RENÉ TOBIAS
    权利人:DSM IP ASSETS BV
    摘要:The present invention relates to synthesis of specific allylic alcohols having terminal carboxyl groups based on steps of ethynylation and hydrogenation in the presence of a Lindlar catalyst. These allylic alcohols are particularly useful to offer pathways to syntheses of isophytol or tocopherols having a terminal carboxyl group by a very small number of reactions steps.

    专利号:US-2022048879-A1
    优先权日:2020-08-13
    标 题:Synthesis of small molecules inspired by Phomoxanthone A
    发明人:ALI RAMEEZ; MATTSON ANITA
    权利人:WORCESTER POLYTECH INST
    摘要:Methods, compositions, and kits are provided for synthesizing bioactive chromane, the method including: constructing a tertiary ether stereocenter enantioselectively by catalyzed alkynylation of a substituted chromenone to obtain a chromanone; reducing alkyne and ketone in the chromanone to obtain a chroman; and converting ester to methyl group thereby obtaining chromane.

    专利号:US-8829238-B2
    优先权日:2011-09-22
    标 题:Methods for the synthesis of deuterated acrylate salts
    发明人:YANG JUN; BONNESEN PETER V; HONG KUNLUN
    权利人:YANG JUN; BONNESEN PETER V; HONG KUNLUN; UT BATTELLE LLC
    摘要:A method for synthesizing a deuterated acrylate of the Formula (1), the method comprising: (i) deuterating a propiolate compound of Formula (2) to a methyne-deuterated propiolate compound of Formula (3) in the presence of a base and D 2 O: and (ii) reductively deuterating the methyne-deuterated propiolate compound of Formula (3) in a reaction solvent in the presence of deuterium gas and a palladium-containing catalyst to afford the deuterated acrylate of the Formula (1). The resulting deuterated acrylate compounds, derivatives thereof, and polymers derived therefrom are also described.

    专利号:US-7074932-B2
    优先权日:1999-06-24
    标题 :Preparation of quinoline-substituted carbonate and carbamate derivatives
    发明人:ALLEN MICHAEL S; PREMCHANDRAN RAMIYA H; CHANG SOU-JEN; CONDON STEPHEN; DEMATTEI JOHN A; KING STEVEN A; KOLACZKOWSKI LAWRENCE; MANNA SUKUMAR; NICHOLS PAUL J; PATEL HEMANT H; PATEL SUBHASH R; PLATA DANIEL J; STONER ERIC J; TIEN JIEN-HEH J; WITTENBERGER STEVEN J
    权利人:ALLEN MICHAEL S; PREMCHANDRAN RAMIYA H; CHANG SOU-JEN; CONDON STEPHEN; DEMATTEI JOHN A; KING STEVEN A; KOLACZKOWSKI LAWRENCE; MANNA SUKUMAR; NICHOLS PAUL J; PATEL HEMANT H; PATEL SUBHASH R; PLATA DANIEL J; STONER ERIC J; TIEN JIEN-HEH J; WITTENBERGER STEVEN J
    摘要:The invention relates to a process for preparing quinoline-substituted carbonate and carbamate compounds, which are important intermediates in the synthesis of 6-O-substituted macrolide antibiotics. The process employs metal-catalyzed coupling reactions to provide a carbonate or carbamate of formula (I) or (II) or a substrate that can be reduced to obtain the same.

    专利号:US-2009111737-A1
    优先权日:1999-05-24
    标题:Novel antibacterial agents
    发明人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
    权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
    摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.
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    主要参考文献

    [参考文献]: Liuchun Yang, Et Al. Imaging Of The Intracellular Topography Of Copper With A Fluorescent Sensor And By Synchrotron X-Ray Fluorescence Microscopy. Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11179-84.

    合成参考文献


    摘要:S13 | EUCOSMETICS | Combined Inventory of Ingredients Employed in Cosmetic Products (2000) and Revised Inventory (2006) | DOI:10.5281/zenodo.2624118
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