专利号:US-2024158926-A1 优先权日:2022-11-03 标 题 :Electrochemical synthesis of hydroxyvaleric acid from levulinic acid 发明人:HOLEWINSKI ADAM; DE SOUZA LUCAS FRANCISCO WILLIAN 权利人:UNIV COLORADO REGENTS 摘要:Disclosed herein are methods of electrochemical synthesis of hydroxyvaleric acid from levulinic acid. For example, disclosed herein are methods comprising electrochemical synthesis of hydroxyvaleric acid from levulinic acid, wherein the method is conducted in an electrochemical cell wherein a working electrode is in electrochemical contact with an aqueous electrolyte and levulinic acid, wherein the method comprises applying a potential to electrochemically reduce the levulinic acid to form hydroxyvaleric acid. Also disclosed herein are methods of synthesizing gamma-valerolactone from hydroxyvaleric acid, the method comprising acid-catalyzed esterification. Also disclosed herein are methods of use of the products produced by any of the methods herein.
专利号:US-4910310-A 优先权日:1988-10-03 标 题:Synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives 发明人:CAMPBELL ARTHUR L; BEHLING JAMES R; BABIAK KEVIN A; NG JOHN S; MUELLER RICHARD A; FLEET GEORGE W J 权利人:SEARLE & CO 摘要:Novel intermediates and method for the chemical synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives are provided. A preferred intermediate is 1,5-dideoxy-1,5-imino-3, 4-O-isopropylidene-L-fucitol which is used to prepare the HIV inhibitor 1,5-dideoxy-1,5-imino-[N-ω-methyl caproate]-L-fucitol. These compounds are prepared in a short synthesis from the known compound 2,3-O-isopropylidene-D-lyxono-1,4-lactone or in a multi-step synthesis from D-galactose.
专利号:US-7314960-B1 优先权日:2006-09-28 标 题:Catalytic synthesis of oxygenate from alcohol 发明人:LIN SHENG-DIANN; HSIAO TING-CHOU 权利人:UNIV YUAN ZE 摘要:The present invention discloses a method for catalytic synthesis of oxygenate from alcohol. At first, a feeding material comprising at least one alcohol is provided. Next, a copper-containing catalyst is provided and the catalyst further comprises at least one metal element selected from the group consisting of the following: zinc, magnesium, and aluminum elements. Following that, a catalytic reaction of the feeding material over the copper-containing catalyst is carried out to synthesize at least one oxygenate.
专利号:US-10882813-B2 优先权日:2014-12-17 标 题:Method for the synthesis of ferric oraganic compounds 发明人:PULLAGURLA MANIK REDDY; NANDA KUMAR MECHERIL VALSAN; RANGISETTY JAGADEESH BABU; BHUDETI RAJESH; NAGARAPU RADHA 权利人:BIOPHORE INDIA PHARMACEUTICALS PVT LTD 摘要:The present invention relates to an improved method for the synthesis of Ferric Citrate and also to provide an amorphous form of Ferric Citrate having an active surface area less than 14 sq.m/g.
专利号:US-8664357-B2 优先权日:2008-08-08 标题 :Solvent resistant diafiltration of peptides, PNA or oligonucleotides 发明人:LIVINGSTON ANDREW GUY; PEEVA LUDMILA GEORGIEVA; SO SHEYUNG WANG JERRY; CAMPOS VASCONCELES RENATO; LEATHERBARROW ROBIN JOHN; TATE EDWARD WILLIAM; GAFFNEY PIERS ROBERT JAMES 权利人:LIVINGSTON ANDREW GUY; PEEVA LUDMILA GEORGIEVA; SO SHEYUNG WANG JERRY; CAMPOS VASCONCELES RENATO; LEATHERBARROW ROBIN JOHN; TATE EDWARD WILLIAM; GAFFNEY PIERS ROBERT JAMES; IMP INNOVATIONS LTD 摘要:According to the present invention, there is provided a process for the preparation of a first compound selected from peptides, oligonucleotides and peptide nucleic acids. The process comprises synthesizing the first compound and then separating the first compound formed in step (i) from a second compound, which is a reaction by-product of the synthesis of the first compound and/or an excess of a reagent used for the synthesis of a first compound by a process of diafiltration. The membrane used for the diafiltration process is stable in organic solvents and provides a rejection for the first compound which is greater than the rejection for the second compound.
专利号:US-3772366-A 优先权日:1964-09-29 标 题 :Process for the preparation of 9beta,10beta steroids 发明人:USKOKOVIC M; WILLIAMS T 权利人:HOFFMANN LA ROCHE 摘要:THE PRESENT INVENTION IS DIRECTED TO A PROCESS FOR THE COMPLETE CHEMICAL SYNTHESIS OF STEROIDS HAVING THE 9B, 10A-CONFIGURATION FROM THE NATURAL STERIOIDS POSSESSING THE 9A, 10B-CONFIGURATION INCLUDING INTERMEDIATES IN THIS SYNTHESIS. THE STEROIDS WITH THE 9B,10A-CONFIGURATION ARE USEFUL AS ANABOLIC AGENTS, ANTI-ANDROGENIC AGENTS, PROGESTATIONAL AGENTS AND AS SALT-RETAINING AGENTS.
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合成参考文献
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