CAS: 2687-91-4; 1-Ethylpyrrolidin-2-One

相似化合物

3470-98-2 2687-94-7 2687-96-9

上下游产品

N-乙基琥珀酰亚胺 N-Ethylsuccinimide 2314-78-5
N-羟乙基-2-吡咯烷酮 1-(2-Hydroxyethyl)-2-Pyrrolidinone 02/11/3445
N-乙烯基吡咯烷酮 1-Vinyl-2-Pyrrolidinone 88-12-0
2-吡咯烷酮 2-Pyrrolidinon 616-45-5

N,N-Diethyl-2-Diazoacetamide置于dirhodium Tetraacetate体系中,用 二氯甲烷 用作溶剂,化学反应 5.0H,以77%的收率获得n-乙基-2-吡咯烷酮
参考文献:通过类固醇ch插入α-重氮乙酰胺形成β-和γ-内酰胺的钌(i,I)催化剂
标题:通过类固醇ch插入α-重氮乙酰胺形成β-和γ-内酰胺的钌(i,I)催化剂
摘要:五个α-重氮乙酰胺[n 2 Chconr 2,Nr 2 = Net 2(3A),Nbu 2(3B),N(i-Pr)2(3C),N(ch 2 Ph)2(3D),N(异pr)(ch 2 Ph)(3E)],使用研究作为催化剂的双核钌(i,I)所述类型的复合物的[ru 2(μ-L 1)2(co)4大号2 2 ],其中l 1是桥接乙酸盐,杯[4]芳烯二羧酸盐,糖精,吡啶-2-油酸酯或三氮烯配体以及[rucl 2(p-Cymene)] 2的双齿.发现ru(i,I)配合物是类胡萝卜素环化反应的合适催化剂,除了3A的情况.使用重氮酰胺3B-e,[ru 2(μ-囊)2(co)5 ] 2(sa C =糖精)和[ru 2(μ-6-氯吡啶-2-醇酸酯)2(ch 3 Cn)2( Co)4 ]与rh 2(oac)4一样有效在相同条件下,尽管观测到环化的区域选择性和化学选择性有些差异.类胡萝卜素环化反应从重氮酰胺3
Doi:10.1002/adsc.200606108

专利信息

专利号:WO-2024256322-A1
优先权日:2023-06-13
标题 :Synthesis of non-ionic radiographic contrast agents by means of reactive extrusion
发明人：LATTUADA LUCIANO; SEBASTIANO ROBERTO; LEONARDI GABRIELLA; CRAVOTTO GIANCARLO; BARGE ALESSANDRO; BUCCIOL FABIO
权利人:BRACCO IMAGING SPA; MILANO POLITECNICO
摘要:The present invention relates to the industrial preparation of non-ionic X-ray contrast agents. In particular, it relates to a process for the synthesis of lopamidol using a reactive extrusion process in continuous which enable an efficient conversion of the relevant key intermediates, preferably in the absence of any solvent. The invention further relates to the preparation of radiographic X-rays contrast agents or key intermediates thereof by exploiting the technology of reactive extrusion.

专利号:WO-2009135600-A1
优先权日:2008-05-07
标题:Catalysts for the synthesis of polyurethanes
发明人：LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN
权利人:BAYER MATERIALSCIENCE AG; LINDNER STEFAN; BAHNMUELLER STEFAN; SCHMIDT AXEL; WEIKARD JAN; BUCHMEISER MICHAEL; BANTU BHASKER; FRIEDERICHS WOLFGANG; KRAUSE JENS; REITER STEPHAN
摘要:The invention relates to novel catalysts for the synthesis of polyurethanes, represented by general formula (I) or (II), or compounds obtained by reacting a metal salt of the metals magnesium, calcium, yttrium, lanthanum, titanium, zirconium, manganese, iron, cobalt, zinc, aluminium, tin, comprising an anion from the group fluoride, chloride, bromide, sulphonate, trifluoromethanesulphonate, methanesulphonate, benzolsulphonate, para-toluenesulphonate, carboxy-C1-C10-alkyl, carboxy-C3-C10-cycloalkyl, carboxy- C2-C10-alkenyl, C1-C10-alkoxy, acetylacetonate, trifluoroacetlyacetonate or hexafluoroacetylacetonate, with N-heterocyclic compounds of general structure I; or with N-heterocyclic compounds of general structure II; or with N-heterocyclic compounds of general structure III.

专利号:WO-2024259491-A1
优先权日:2023-06-23
标 题:New synthesis method
发明人：FORD DANIEL; POZNAKS VIKTORS; FOTINS JURIS; ÄŒERÅ…AKS DMITRIJS
权利人:THE HEART RES INSTITUTE LTD
摘要:The present disclosure generally relates to a process for the synthesis of AZD6482. In particular, the present disclosure also relates to a process for the synthesis of enantiomerically pure AZD6482. The present disclosure also relates to a process for the synthesis of enantiomerically pure intermediates. The present disclosure also relates to compounds prepared by the processes and the use of such compounds to prepare compositions and to treat disorders.

专利号:US-8664357-B2
优先权日:2008-08-08
标题 :Solvent resistant diafiltration of peptides, PNA or oligonucleotides
发明人：LIVINGSTON ANDREW GUY; PEEVA LUDMILA GEORGIEVA; SO SHEYUNG WANG JERRY; CAMPOS VASCONCELES RENATO; LEATHERBARROW ROBIN JOHN; TATE EDWARD WILLIAM; GAFFNEY PIERS ROBERT JAMES
权利人:LIVINGSTON ANDREW GUY; PEEVA LUDMILA GEORGIEVA; SO SHEYUNG WANG JERRY; CAMPOS VASCONCELES RENATO; LEATHERBARROW ROBIN JOHN; TATE EDWARD WILLIAM; GAFFNEY PIERS ROBERT JAMES; IMP INNOVATIONS LTD
摘要:According to the present invention, there is provided a process for the preparation of a first compound selected from peptides, oligonucleotides and peptide nucleic acids. The process comprises synthesizing the first compound and then separating the first compound formed in step (i) from a second compound, which is a reaction by-product of the synthesis of the first compound and/or an excess of a reagent used for the synthesis of a first compound by a process of diafiltration. The membrane used for the diafiltration process is stable in organic solvents and provides a rejection for the first compound which is greater than the rejection for the second compound.

专利号:US-8093378-B2
优先权日:2006-04-28
标题 :Crystallization method for intermediates of carbapenem antibiotics
发明人：NISHINO KEITA; KOGA TERUYOSHI; FUKAE MASAFUMI; UEDA YASUYOSHI
权利人:NISHINO KEITA; KOGA TERUYOSHI; FUKAE MASAFUMI; UEDA YASUYOSHI; KANEKA CORP
摘要:An improved crystallization method for an azetidinone compound represented by the formula 1: , which is extremely useful as a common intermediate for the synthesis of 1β-methylcarbapenem compounds. The present method provides crystals having higher quality and stability than conventional crystals and excellent filterability at the time of recovery; and an azetidinone compound having a low content of impurity, and which has a controlled particle size distribution of crystals and improved handleability and stability. The crystallization is carried out by adding a hydrocarbon solvent to a solution in which an azetidinone compound extremely useful as a common intermediate for the synthesis of 1β-methylcarbapenem compounds is dissolved in the presence of a seed crystal in an amount of 200% by weight or less based on the weight of the azetidinone compound.

专利号:US-8557979-B2
优先权日:2004-06-10
标题 :Carbapenem antibacterials with gram-negative activity and processes for their preparation
发明人：CHOI WOO-BAEG; KOWALIK EWA
权利人:CHOI WOO-BAEG; KOWALIK EWA; FOB SYNTHESIS INC
摘要:The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of β-methyl carbapenems which are useful as antibacterial agents.