CAS: 23095-31-0; 3,4-Dimethoxybenzenesulfonyl Chloride

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CAS号91-16-7 1,2-二甲氧基苯 | CAS号199666-03-0 3,4-二甲氧基-N-[4-(... | CAS号2570-43-6 3,4-二甲氧基硫代苯甲醚 | CAS号700-96-9 3,4-二甲氧基苯硫酚 | CAS号79440-51-0 1-(4,5-dimethox... | CAS号91908-88-2 1-[(3,4-二甲氧基苯基)... | CAS号93129-41-0 {[((3,4-二甲氧基苯基)... | CAS号63624-27-1 3,4-二甲氧基苯-1-磺酰胺 | CAS号41079-73-6 2,3,7,8-tetrame...

邻苯二甲醚置于氯磺酸体系中,用69%的收率获得3,4-二甲氧基苯磺酰氯
参考文献:涉及未活化的烷基溴的三组分,间断的自由基/烯丙基取代级联
标题:涉及未活化的烷基溴的三组分,间断的自由基/烯丙基取代级联
摘要:开发有效和选择性的策略来处理包含(多)立体中心的复杂架构,一直是学术界和工业界的一个长期综合挑战.催化级联反应代表了一种从简单原料中快速利用分子复杂性的有力手段.不幸的是,由于不可避免的 β-氢化物消除,进行涉及未活化(叔)烷基卤化物的级联 Heck 型反应仍然是一个未解决的挑战.在此,我们展示了模块化,实用且通用的钯催化的自由基三组分偶联确实可以通过可见光介导的中断的 Heck/烯丙基取代序列克服上述限制.未活化的 1,3-二烯(如丁二烯)的选择性 1,4-双官能化,通过使用不同的市售氮基,氧基,硫基或碳基亲核试剂和未活化的烷基溴(>130 个实例,大多数 >95:5 E/z,>20:1 Rr)实现了这一目标.连续的 C(Sp3)-C(Sp3) 和 Cx (N,O,S) 键已被有效构建,具有广泛的范围和高官能团耐受性.该策略的灵活性和多功能性已在复杂醚,砜和叔胺产品的克级反应和流线型合成
Doi:10.1021/jacs.0C03239

专利信息

专利号:US-8138272-B2
优先权日:2006-05-22
标 题:Preparation of polymer conjugates of therapeutic, agricultural, and food additive compounds
发明人：KONRADI ANDREI W; SMITH JENIFER L
权利人:KONRADI ANDREI W; SMITH JENIFER L; ELAN PHARM INC
摘要:This invention provides an improved synthesis of polymer conjugates of formula (I), n nof agricultural, therapeutic, and food additive compounds. In particular, a process is described for the preparation of conjugates by treating primary or secondary alcohol substituents of active compounds with polymeric nucleophiles using “Mitsunobuâ€? or related reaction conditions.

专利号:WO-0053579-A2
优先权日:1999-03-10
标 题:Solid phase synthesis of 4-aminoproline derivatives and/or combinatorial libraries thereof

专利号:US-10246411-B2
优先权日:2014-10-29
标 题:(Z)-3,4,5-trimethoxystyrylbenzenesulfonamides as potential anticancer agents
发明人：KAMAL AHMED; RASALA MAHESH; RATNA REDDY CHALLA; BHARATH KUMAR GAJJELA; SASTRY VISWESWARA; BASHA SHAIK ANVER; SANTHOSH REEDY VANGALA
权利人:COUNCIL SCIENT IND RES
摘要:This present invention relates to (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides of general formula A. The invention also provides the synthesis of (Z)-3,4,5-trimethoxystyrylbenzenesulfonamides useful as potential antitumor agents against human cancer cell lines and a process for the preparation thereof.

专利号:US-2008194629-A1
优先权日:2005-05-03
标题 :3-Mono-and 3,5-Disubstituted Piperidine Derivatives as Renin Inhibitors
发明人：BAESCHLIN DANIEL KASPAR; BREITENSTEIN WERNER; EHRHARDT CLAUS; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; ZIMMERMANN JUERG; RUDISSER SIMON; VANGREVELINGHE ERIC; IRIE OSAMU; UMEMURA ICHIRO; SUZUKI MASAKI; MOGI MUNETO; KANAZAWA TAKANORI; YOKOKAWA FUMIAKI; NIHONYANAGI ATSUKO
权利人:BAESCHLIN DANIEL KASPAR; BREITENSTEIN WERNER; EHRHARDT CLAUS; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; ZIMMERMANN JUERG; RUDISSER SIMON; VANGREVELINGHE ERIC; IRIE OSAMU; UMEMURA ICHIRO; SUZUKI MASAKI; MOGI MUNETO; KANAZAWA TAKANORI; YOKOKAWA FUMIAKI; NIHONYANAGI ATSUKO
摘要:The invention relates to 3,5-piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-piperidine compound, and/or a method of treatment comprising administering a 3,5-piperidine compound, a method for the manufacture of a 3,5-piperidine compound, and novel intermediates and partial steps for their synthesis. Especially, the 3,5-piperidine compounds have the formula I, wherein the symbols have the meanings described in the specification.

专利号:WO-2011006000-A1
优先权日:2009-07-08
标题 :Berberine derivatives useful for modulating lipid levels and their methods of synthesis

专利号:RU-2194044-C2
优先权日:1997-10-01
标 题 :Derivatives of benzamidine, method of their synthesis and pharmaceutical composition