CAS: 2305-26-2; (1R,2S)-Rel-Cyclohex-4-Ene-1,2-Dicarboxylic Acid

相似化合物

88-98-2 17673-68-6 4841-84-3

上下游产品

buta-1,3-diene maleic acid cis-1,2,3,6-tetrahydrophthalic anhydride (1R,2S)-Cyclohex-4-ene-1,2-dicarbonitrilecyclohex-4-ene-1,2-dicarboxylic acid dipropyl ester Tetrahydrophthalsaeure-dipentylester cyclohex-4-ene-1,2-dicarboxylic acid diisopropyl ester dibutyl cyclohex-4-ene-1,2-dicarboxylate

📜Cis-1,2,3,6-Tetrahydrophthalic Anhydride 在 盐酸体系中,用 水,溶剂黄146作为反应溶剂,以100%的收率获得cis-1,2,3,6-Tetrahydrophthalic Acid
参考文献:新的三氯铂π配合物的合成和结构:配体中氮孤对与c-C双键π电子的反应性,位阻的影响
标题:新的三氯铂π配合物的合成和结构:配体中氮孤对与c-C双键π电子的反应性,位阻的影响
摘要:在尝试合成叔环己烷1,4-二胺的相应顺铂方平面络合物的尝试中,意外地分离了两个三氯铂π络合物和四氯铂酸二铵(II)盐.所有三种化合物均经过物理和光谱表征,包括三种化合物中两种化合物的x射线衍射分析.形成π-络合物而不是二氨基顺式-铂络合物可以解释为由于甲基在叔胺上施加的空间位阻.因此,Cc双键的π电子比来自氨基的氮原子的电子孤对更容易获得.当通过将环己烯亚基转化为苯芳香环而使配体分子中cc的π电子不可用时,没有分离出顺式-二氨基二氯铂(II)络合物或三氯铂络合物,而是相应的四氯铂酸酯(II) 1,4-二氨基配体的二铵盐.
Doi:10.1016/J.Jorganchem.2005.07.095

专利信息

专利号:US-2004249114-A1
优先权日:2001-02-06
标题 :Methods of synthesis of polysuccinimide or polyaspartate by end capping polymerization
发明人：SWIFT GRAHAM; REDLICH GEORGE H; WEHBY JOHN NOLAN
摘要:Disclosed are methods of synthesis of homopolymers or copolymers containing succinimide or aspartate moieties formed in the presence of an end capping initiator. Also disclosed are methods of isolating, compounding, stabilizing and processing the homopolymers and copolymers.

专利号:US-2006211843-A1
优先权日:2001-02-06
标题:Methods of synthesis of poly(succinimide-aspartate) polysuccinimide or polyaspartate by end capping polymerization
发明人：SWIFT GRAHAM; REDLICH GEORGE H
权利人:SWIFT GRAHAM; REDLICH GEORGE H
摘要:Disclosed are methods of synthesis of homopolymers or copolymers containing succinimide or aspartate moieties formed in the presence of an end capping initiator. Also disclosed are methods of isolating, compounding, stabilizing and processing the homopolymers and copolymers.

专利号:US-2004249115-A1
优先权日:2001-02-06
标题 :Methods of synthesis of poly(succinimide-aspartate) copolymer by end-capping polymerization
发明人：SWIFT GRAHAM; REDLICH GEORGE H
摘要:Disclosed are methods of synthesis of copoly(succinimide-aspartate), copolymers and derivatives thereof, prepared in a thermal or supercritical fluid method in the presence of an end capping initiator. Also disclosed are methods of isolating, compounding, stabilizing and processing the copoly(succinimide-aspartate), and its derivatives.

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:WO-2007104357-A1
优先权日:2006-03-14
标 题 :Synthesis of amines with catalytic amounts of mild lewis acids
发明人：NUGENT THOMAS CHRISTOPHER; WAKCHAURE VIJAY NARAYAN; EL-SHAZLY MOHAMED MAHMOUD
权利人:UNIV JACOBS BREMEN GMBH; NUGENT THOMAS CHRISTOPHER; WAKCHAURE VIJAY NARAYAN; EL-SHAZLY MOHAMED MAHMOUD
摘要:The invention relates to methods for producing primary, secondary and tertiary amines and corresponding enantiopure or enantioenriched primary or secondary amine products, comprising the steps of reductively aminating a ketone, with a nitrogen auxiliary in the presence of a hydrogenating catalyst and a hydrogenating agent, wherein the reductive animation is performed under the influence of a mild Lewis acid, the mild Lewis acid being present at the onset of the reductive amination in at most 25 mol% of the ketone or the nitrogen auxiliary.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.