CAS: 20942-99-8; (2R,3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)Hexane-1,2,3,4,5-Pentaol

上下游产品

CAS号69-65-8 甘露醇 | CAS号50-99-7 D(+)-无水葡萄糖

📜蔗糖置于镍 氢气体系中,用 水 用作溶剂,30.0~120.0 °C,12.0 Mpa 条件下,反应 28.0H,反应生成1-O-Alpha-D-吡喃葡萄糖-D-甘露糖醇二水合物
参考文献:1-O-α-D-Glucopyranosyl-D-Fructose: Darstellung Aus Saccharose Und Ihre Reduktion Zu 1-O-α-D-Glucopyranosyl-D-Glucitol
标题:1-O-α-D-Glucopyranosyl-D-Fructose: Darstellung Aus Saccharose Und Ihre Reduktion Zu 1-O-α-D-Glucopyranosyl-D-Glucitol
摘要:
Doi:10.1016/0008-6215(87)80152-0

专利信息

专利号:US-2006030625-A1
优先权日:2004-08-06
标 题 :Dietary neurotransmitter precursors for balanced synthesis of neurotransmitters
发明人：HART CHERYLE RAM; GROSSMAN RONALD S; RAM HERBERT
权利人:HART CHERYLE RAM; GROSSMAN RONALD S; RAM HERBERT
摘要:Dietary supplements for treating a neurotransmitter deficiency include one or more precursors of the deficient neurotransmitter and a cofactor for activating in vivo enzymatic synthesis of the deficient neurotransmitter. The dietary supplements can also include an appropriate neurotransmitter, such as an amino acid. When administered through the oral mucosa, increases in levels of the deficient neurotransmitters and relief from deficiency symptoms are obtained.

专利号:US-11692058-B2
优先权日:2021-02-26
标题:Synthesis of functional polyurethanes and polyesters from biomass-derived monomers
发明人：CHANG HOCHAN; HUBER GEORGE W; DUMESIC JAMES A
权利人:WISCONSIN ALUMNI RES FOUND
摘要:A method of making polyesters and polyurethanes from biomass-derived polyols. The polyol is biomass-derived and has the structure:wherein dashed bonds are single or double bonds and R is selected from the group consisting of —OH and â• O. Polyurethanes are made by reacting the polyol with a diisocyanate. Polyesters are made by reacting the polyol with a dicarboxylic acid.

专利号:US-9090550-B2
优先权日:2010-07-30
标 题:Microwave assisted synthesis of dehydrated sugar derivatives hydroxymethylfurfural, levulinic acid, anhydrosugar alcohols, and ethers thereof
发明人：HOWARD STEPHEN J; SANBORN ALEXANDRA J
权利人:HOWARD STEPHEN J; SANBORN ALEXANDRA J; ARCHER DANIELS MIDLAND CO
摘要:Methods for the production of dehydrated sugars and derivatives of dehydrated sugars using microwave (MW) irradiation and methods of purifying the same are described. The dehydrated sugars derivatives include 5-hydroxymethyl-2-furfural (HMF) and anhydrosugar alcohols such as sorbitans and isosorbide. The derivatives include HMF ethers, levulinic acid esters, and ether derivatives of the anhydrosugar alcohols. The described methods require lower reaction temperatures and shorter reaction times than similar non microwave mediated reactions known in the art. Typical reaction conditions are 120-210° C., and typical reaction times are 30 minutes or less.

专利号:US-10287265-B2
优先权日:2015-03-09
标 题 :Enantiomers of 8-hydroxyquinoline derivatives and the synthesis thereof
发明人：Puskás László; Kanizsai István; PILLOT THIERRY; GYURIS Márió; Szabó András; Takács Ferenc; Hackler László
权利人:AVIDIN CO LTD; SONEAS RES CO LTD; SYNAGING SAS
摘要:Our invention relates to novel enantiomer derivatives of 8-hydroxyquinoline derivatives with general formula (I) and (II) and the synthesis thereof and pharmaceutically acceptable salts and metal complexes thereof, and the medicinal and/or pharmaceutical compositions comprising these compounds. n n n n n n n n n n The essence of the subject matter of the invention relates to the fact that prior art discloses the biological effect and characteristics only of the racemic products, the novel enantiomer derivatives according to the invention appear in our application for the first. n The subject matter of the invention furthermore relates to a novel, stereoselective synthesis for the preparation of the novel enantiomer derivatives according to the invention. The novel medicinal and/or pharmaceutical compositions comprising these enantiomers are suitable for the treatment of the named diseases, and the enanatiomers are used for manufacture of these compositions. These applications for manufacture of the compositions are also the subject matters of the invention. The compounds according to the invention can be used preferably as cytoprotective, neuroprotective, cardioprotective, anxiolytic and antidepressant agent for treatment of neuropsychiatric and neurologic diseases and diseases in connections with transplantations and with ischemia and reperfusion injuries thereof, and inhibition of organ, advantageously skin graft rejection. According to our studies the R-enantiomer has either sole or high biological effect in some cases.

专利号:US-11679182-B2
优先权日:2019-02-20
标题 :Methods of synthesis for a thioketal diol
发明人：HARRINGTON ROGER E; JACOBS JERBRENA C; DOYLE ROBERT
权利人:WARSAW ORTHOPEDIC INC
摘要:A method of making a hydroxyl-terminated thioketal diol is provided, the method comprising reacting a thioketal ester with a non-pyrophoric reducing agent to form a hydroxyl-terminated thioketal diol. The hydroxyl-terminated thioketal diol can be 2,2-(propane-2,2-diylbis(sulfanediyl)) diethanol. The non-pyrophoric reducing agent can be a sodium aluminum hydride, for example, sodium bis (2-methoxyethoxy)aluminum hydride. The thioketal ester can be dimethyl 2,2-(propane-2,2-diylbis(sulfanediyl)) diacetate. A biodegradable matrix prepared by reacting a hydroxyl-terminated thioketal diol with an isocyanate is provided. A method of making a biodegradable polyurethane composite is also provided.

专利号:US-2015133460-A1
优先权日:2013-11-11
标题:Lactate salt of 4-[6-methoxy-7-(3-piperidin-1-yl-propoxy)quinazolin-4-yl]piperazine-1-carboxylic acid(4-isopropoxyphenyl)-amide and pharmaceutical compositions thereof for the treatment of cancer and other diseases or disorders
发明人：ARMITAGE Ian; FERDOUS ABU J; BOURLAND MICHAEL E; BOYLE CRAIG S J; COOPER MARTIN IAN; LANGSTON MARIANNE
权利人:MILLENNIUM PHAMACEUTICALS INC
摘要:This invention provides a compound of formula (I): n n n n n n n n n n n n or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof; processes for the synthesis or manufacture of the compound of formula (I), or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof; and the use of said compound, or a crystalline form thereof, or a pharmaceutical composition thereof, or an oral pharmaceutical dosage form thereof, for the treatment of patients suffering from or subject to diseases, disorders or conditions involving cell survival, proliferation, and migration, including cardiovascular disease (e.g., arteriosclerosis and vascular reobstruction), cancer, (e.g., AML and malignant glioma) glomerulosclerosis, fibrotic disease and inflammation.