CAS: 18163-07-0; 2-Propenyltrimethylsilane

上下游产品

chloro-trimethyl-silane 2-bromoprop-1-ene 2,2-bis(allyloxy)hexamethyltrisilane trimethylsilyl trifluoromethanesulfonate t-butyldimethylsiyl triflate E-1-chloro-2-methyl-2-trimethylsilyl-cyclopropyl phenyl sulfide Z-1-chloro-2-methyl-2-trimethylsilyl-cyclopropyl phenyl sulfide

三甲基-丙-2-基硅烷置于溴体系中,用 乙醇 用作溶剂,化学反应生成2-烯丙基三甲基硅烷
参考文献:叔α-甲硅烷基溴化物的溶剂分解机理
标题:叔α-甲硅烷基溴化物的溶剂分解机理
摘要:报道了式rme 2 Sicme 2 Br,(i)的化合物的制备和性质.(ia)(r = Me)在乙醇水溶液中的溶剂分解导致消除,从而以高收率生产异丙烯基三甲基硅烷.溶剂,添加的盐和r的变化对(i)溶剂分解速率的影响可以通过过渡态来合理化,该过渡态包括与si相邻的碳原子上的大量电子缺乏.当r是取代的苯基基团时,没有证据表明存在苯基参与达到过渡态,如对于类似碳化合物所提出的.(i)和碳类似物的溶剂分解的相对速率与碳离子稳定性有关.
Doi:10.1016/s0022-328X(00)88183-8

专利信息

专利号:US-10005720-B2
优先权日:2013-04-05
标题:Compounds useful for the treatment of metabolic disorders and synthesis of the same
发明人：SEXTON JONATHAN Z; BRENMAN JAY E; MUSSO DAVID L
权利人:NORTH CAROLINA CENTRAL UNIV; UNIV NORTH CAROLINA CHAPEL HILL
摘要:The present invention provides compounds of Formula (I): wherein variables X, Y, Z and R1 are as described herein. Some of the compounds described herein are glutamate dehydrogenase activators. The invention is also directed to pharmaceutical compositions comprising these compounds, uses of these compounds and compositions in the treatment of metabolic disorders as well as synthesis of the compounds.

专利号:US-8962858-B2
优先权日:2011-01-21
标题 :Methods and compounds useful in the synthesis of fused aminodihydrothiazine derivatives
发明人：MITASEV BRANKO; KIM DAE-SHIK; ZHANG HUIMING; FARTHING CHRISTOPHER N
权利人:EISAI R&D MAN CO LTD
摘要:Provided are compounds and methods useful for the preparation of compounds useful as inhibitors of beta-site amyloid precursor protein (APP)-cleaving enzyme.

专利号:US-9828336-B2
优先权日:2012-02-17
标题:Methods and compounds useful in the synthesis of orexin-2 receptor antagonists
发明人：MONIZ GEORGE ANTHONY; WILCOXEN ANNIE ZHU; BENAYOUD FARID; TANAKA TOSHIAKI; SORIMACHI KEIICHI
权利人:EISAI R&D MAN CO LTD
摘要:The present disclosure provides compounds and methods that are useful for the preparation of compounds useful as orexin-2 receptor antagonists.

专利号:US-2018370905-A1
优先权日:2013-04-05
标题:Compounds Useful for the Treatment of Metabolic Disorders and Synthesis of the Same

专利号:US-11767388-B1
优先权日:2019-09-18
标 题 :Silicon-functionalized rubber
发明人：ENSIGN SETH CODY; VIELHABER MARGARET FLOOK; JOHNGRASS JENA LYNN; MA LIQING
权利人:GOODYEAR TIRE & RUBBER
摘要:The compatibility between silica fillers and synthetic rubbers which are synthesized utilizing lanthanide-based catalyst systems, such as neodymium catalyst systems can be improved by terminating the polymerization with a vinyl silane terminating agent. In doing so the vinyl silane is allowed to react with the polymer chain ends of the neodymium rubber to functionalize the chain ends of the polymer chains with silicon containing groups. This results in the rubber having better characteristics for utilization in tire rubber formulations, such a tire tread formulations, that exhibit improved wear characteristics and lower rolling resistance. The process for the synthesis of such functionalized polydiene rubber comprises (1) polymerizing a diene monomer in the presence of a lanthanide-based catalyst system, and (2) terminating the polymerization with a vinyl silane terminator. The functionalized polydiene rubber composition made by this method is comprised of a polydiene rubber which is functionalized at its chain ends with a silicon containing group.

专利号:US-10793581-B2
优先权日:2014-08-04
标 题 :Stereochemically defined polypropionates and methods for making and using the same
发明人：FANG FRANCIS G; CHOI HYEONG-WOOK; CAMPAGNA SILVIO; MATHIEU STEVEN
权利人:EISAI R&D MAN CO LTD
摘要:The present invention relates to stereochemically defined polypropionates and methods for preparing and using the same. The stereochemically defined polypropionates may be useful in the synthesis of natural products and/or natural product-like libraries.