CAS: 149376-67-0; 2-(6-(((Benzyloxy)Carbonyl)Amino)-9H-Purin-9-yl)Acetic Acid

相似化合物

186046-99-1 186046-80-0 169287-69-8

上下游产品

6-(benzyloxycarbonyl)adenin-9-yl)acetateethyl (N6-(benzyloxycarbonyl)adenin-9-yl)acetate ethyl 2-(9H-adenin-9-yl)acetate 1-(benzyloxycarbonyl)-3-ethylimidazolium tetrafluoroborate adenine 6-(benzyloxycarbonyl)adenin-9-yl)acetyl)-N-(2-B°C-aminoethyl)glycinateethyl N-((N6-(benzyloxycarbonyl)adenin-9-yl)acetyl)-N-(2-B°C-aminoethyl)glycinate 6-(benzyloxycarbonyl)adenin-9-ylacetyl)-β-alanine ethyl esterN-(carbamoylmethyl)-N-(N6-(benzyloxycarbonyl)adenin-9-ylacetyl)-β-alanine ethyl ester [[2-(6-Benzyloxycarbonylamino-purin-9-yl)-acetyl]-((1S,2S)-2-tert-butoxycarbonylamino-cyclohexyl)-amino]-acetic acid ethyl ester 6-benzyloxycarbonyl-adeninacetyl-amino]-ortho-chlorophenylacetic acid-(cyclohexen-1-yl)-amiderac-2-[(2-tert-butyloxycarbonyl-aminoethyl)-N6-benzyloxycarbonyl-adeninacetyl-amino]-ortho-chlorophenylacetic acid-(cyclohexen-1-yl)-amide

专利信息

专利号:US-6756199-B1
优先权日:1994-02-23
标题:Peptide nucleic acid combinatorial libraries and improved methods of synthesis
发明人：COOK PHILLIP DAN; KIELY JOHN; SPRANKLE KELLY
权利人:ISIS PHARMACEUTICALS INC
摘要:New sub-monomer synthetic methods for the preparation of peptide nucleic acid oligomeric structures are disclosed that provide for the synthesis of both predefined sequence peptide nucleic acid oligomers as well as random sequence peptide nucleic acid oligomers. Further these methods also provide for the incorporation of peptide nucleic acid units or strings of such units with amino acids or strings of amino acids in chimeric peptide nucleic acid-amino acid compounds. Further disclosed are method of making random libraries of peptide nucleic acids using the fully preformed monomers. Chimeric oligomers and libraries of the same are also disclosed.

专利号:US-7411065-B2
优先权日:2002-04-26
标 题 :PNA monomer and precursor
发明人：KIM SUNG KEE; LEE HYUNIL; LIM JONG CHAN; CHOI HOON; JEON JAE HOON; AHN SANG YOUL; LEE SUNG HEE; YOON WON JUN
权利人:PANAGENE INC
摘要:This application relates to monomers of the general formula (I) for the preparation of PNA (peptide nucleic acid) oglimers and provides method for the synthesis of both predefined sequence PNA oligomers and random sequence PNA oligomers: n nwhereinn E is nitrogen or C—R′; J is sulfur or oxygen; R′, R1, R2, R3, R4 is independently H, halogen, alkyl, nitro, nitrile, alkoxy, halogenated alkyl, halogenated alkoxy, phenyl or halogenated phenyl, R5 is H or protected or unprotected side chain of natural or unnatural α-amino acid; and B is a natural or unnatural nucleobase, wherein when said nucleobase has an exocyclic amino function, said function is protected by protecting group which is labile to acids but stable to weak to medium bases in the presence of thiol.

专利号:US-7022851-B2
优先权日:2002-01-24
标题 :PNA monomer and precursor
发明人：KIM SUNG KEE; LEE HYUNIL; LIM JONG CHAN; CHOI HOON; JEON JAE HOON; AHN SANG YOUL; LEE SUNG HEE
权利人:PANAGENE INC
摘要:This application relates to monomers of the general formula (I) for the preparation of PNA (peptide nucleic acid) oligomers and provides method for the synthesis of both predefined sequence PNA oligomers and random sequence PNA oligomers: n nwhereinn R1, R2, R3, R4, R5 is independently H, halogen, C 1 –C 4 alkyl, nitro, nitrile, C 1 –C 4 alkoxy, halogenated C 1 –C 4 alkyl, or halogenated C 1 –C 4 alkoxy, wherein at least one of R1, R3, and R5 is nitro; R6 is H or protected or unprotected side chain of natural or unnatural α-amino acid; and B is a natural or unnatural nucleobase, wherein when said nucleobase has an exocyclic amino function, said function is protected by protecting group which is labile to acids but stable to weak to medium bases.

专利号:KR-20030084444-A
优先权日:2002-04-26
标 题 :A Novel Monomer For Synthesis of PNA Oligomer And A Process For Producing The Same

专利号:EP-0777678-B1
优先权日:1994-02-23
标 题:Pna combinatorial libraries and improved methods of synthesis

专利号:WO-9523163-A1
优先权日:1994-02-23
标题 :Pna combinatorial libraries and improved methods of synthesis