CAS: 132286-77-2; (S)-4-(Allyloxy)-2-((Tert-Butoxycarbonyl)Amino)-4-Oxobutanoic Acid

相似化合物

146982-24-3 177609-12-0 1676-90-0

上下游产品

CAS号24424-99-5 二碳酸二叔丁酯

📜N-Tert-Butyloxycarbonyl-L-Aspartic Diallyl Ester置于alcalase-Cross-Linked-Enzyme-Aggregates体系中,用 叔丁醇 用作溶剂,化学反应 16.0H,以87%的收率获得boc-L-天冬氨酸 4-烯丙酯
参考文献:A Versatile And Selective Chemo-Enzymatic Synthesis Of β-Protected Aspartic And γ-Protected Glutamic Acid Derivatives
标题:A Versatile And Selective Chemo-Enzymatic Synthesis Of β-Protected Aspartic And γ-Protected Glutamic Acid Derivatives
摘要:Two Versatile,High Yielding,And Efficient Chemo-Enzymatic Methods For The Synthesis Of Beta-Protected Asp And Gamma-Protected Glu Derivatives Using Alcalase Are Described. The First Method Is Based On The Alpha-Selective Enzymatic Hydrolysis Of Symmetrical Aspartyl And Glutamyl Diesters. The Second Method Involving Mixed Diesters Comprises A Three-Step Protocol Using (I) Alpha-Selective Enzymatic Methyl-Esterification,(II) Chemical Beta-Esterification,And Finally (III) Alpha-Selective Enzymatic Methyl Ester Hydrolysis. The Yields Of The Purified Beta-And Gamma-Esters Range From 77% To 91%. (C) 2009 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tetlet.2009.03.130

专利信息

专利号:CN-115103854-A
优先权日:2019-12-16
标题:Synthesis of amanita and its derivatives

专利号:DE-69218193-T2
优先权日:1991-04-25
标 题 :Process for the synthesis of peptides, derivatives of amino acids for use in the above process and methods for their preparation.

专利号:EP-4077353-A1
优先权日:2019-12-16
标 题 :Synthesis of amanin and its derivatives