CAS: 123-99-9; Azelaic Acid

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3788-56-5 3937-56-2 624-17-9

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CAS号112-80-1 油酸 | CAS号112-62-9 油酸甲酯 | CAS号137-21-3 °Ctadecanedioic... | CAS号24753-49-9 ω-carboxyl OA d... | CAS号120-87-6 9,10-二羟基硬脂酸 | CAS号37056-34-1 8-cyano°Ctanoic acid | CAS号14436-32-9 9-癸烯酸 | CAS号141-22-0 蓖麻油酸 | CAS号373-49-9 棕榈油酸 | CAS号112-79-8 反油酸 | CAS号105-03-3 bis(2-ethylbuty... | CAS号106664-96-4 Nonanedioic aci... | CAS号3788-56-5 9-羟基壬酸 | CAS号4080-95-9 壬二酸二酰肼 | CAS号593-49-7 二十七烷 | CAS号4549-33-1 1,9-二溴壬烷 | CAS号4549-31-9 1,7-二溴庚烷 | CAS号34957-73-8 9-羟基正壬酸甲酯 | CAS号3937-56-2 1,9-壬二醇 | CAS号502-49-8 环辛酮

在 氢气体系中,用 水 用作溶剂,200.0 °C,2.0 Mpa 条件下,反应 12.0H,以86%的收率获得壬二酸
参考文献:一种生物质基壬二酸的制备方法
标题:一种生物质基壬二酸的制备方法
摘要:本发明公开了一种生物质基壬二酸的制备方法.该方法包括下述步骤:1)在水溶液中,5‑甲酰基‑2‑呋喃甲酸和丙酮酸在碱催化剂上发生羟醛缩合反应,生成c9缩合产物;2)在加氢催化剂上,C9缩合产物发生加氢反应,生成c9饱和产物;3)在氢解催化剂上,C9饱和产物发生氢解反应,生成壬二酸.本发明以生物质基平台分子为反应原料,使用水作为反应溶剂,采用易于回收利用的多相催化剂,且催化剂具有较高的催化活性和循环稳定性,反应过程绿色无污染,对环境友好.

专利信息

专利号:US-4835247-A
优先权日:1988-08-08
标 题:Process for the synthesis of a copolyester adhesive resin
发明人：WILSON JOHN R; ROUSEK MARIAN M; MASSEY FRED L
权利人:GOODYEAR TIRE & RUBBER
摘要:Isophthalic acid is commonly utilized as a comonomer in the preparation of copolyester resins which are utilized as solution adhesives. Unfortunately, solutions of such resins frequently become hazy due to the presence of cyclic oligomers. This invention is based upon the unexpected discovery that the presence of protonic acids during the synthesis of the copolyester resins containing isophthalic acid utilizing conventional metallic catalysts results in solutions of the resins in organic solvents being virtually haze free. The subject invention more specifically reveals a process for synthesizing a polyethylene terephthalate/isophthalate/azelate copolyester resin which is particularly useful as a solution adhesive resin, comprising reacting ethylene glycol with a diacid component which is comprised of (a) from about 25 to about 45 mole percent terephthalic acid, (b) from about 10 to about 30 to about 55 mole percent azelaic acid based upon the diacid component; in the presence of at least one metallic catalyst selected from the group consisting of antimony compounds, titanium compounds; manganese compounds, and germanium compounds and in the presence of at least one protonic acid having a pKa of less than about 2.5; wherein the amount of metallic catalyst present is within the rang eof about 130 ppm to about 1500 ppm and wherein the amount of protonic acid present is within the range of about 50 ppm to about 500 ppm, with said amounts being based upon the weight of the copolyester resin produced.

专利号:US-4921929-A
优先权日:1988-08-08
标 题:Process for the synthesis of a copolyester adhesive resin
发明人：WILSON JOHN R; ROUSEK MARIAN M; MASSEY FRED L
权利人:GOODYEAR TIRE & RUBBER
摘要:Isophthalic acid is commonly utilized as a comonomer in the preparation of copolyester resins which are utilized as solution adhesives. Unfortunately, solutions of such resins frequently become hazy due to the presence of cyclic oligomers. This invention is based upon the unexpected discovery that the presence of protonic acids during the synthesis of the copolyester resins containing isophthalic acid utilizing conventional metallic catalysts results in solutions of the resins in organic solvents being virtually haze free. The subject invention more specifically reveals a process for synthesizing a polyethylene terephthalate/isophthalate/azelate copolyester resin which is particularly useful as a solution adhesive resin, comprising reacting ethylene glycol with a diacid component which is comprised of (a) from about 25 to about 45 mole percent terephthalic acid, (b) from about 10 to about 30 mole percent isophthalic acid, and (c) from about 30 to about 55 mole percent azelaic acid based upon the diacid component; in the presence of at least one metallic catalyst selected from the group consisting of antimony compounds, titanium compounds; manganese compounds, and germanium compounds and in the presence of at least one protonic acid having a pKa of less than about 2.5; wherein the amount of metallic catalyst present is within the range of about 130 ppm to about 1500 ppm and wherein the amount of protonic acid present is within the range of about 50 ppm to about 500 ppm, with said amounts being based upon the weight of the copolyester resin produced.

专利号:WO-2024042405-A1
优先权日:2022-08-26
标 题:Compositions and methods for the synthesis of bio-based polymers
发明人：OLIVEIRA ANA; CAPÊTO ANA PAULA; PINTADO MANUELA
权利人:AMYRIS BIO PRODUCTS PORTUGAL UNIPESSOAL LTDA; UNIV CATOLICA PORTUGUESA
摘要:The present disclosure provides compositions and methods for the synthesis of bio-based polymers (e.g., polyurethanes and polyesters) from secondary materials produced during a fermentation process. The disclosure also features intermediates produced during these processes, as well as compositions containing the same.

专利号:US-9662347-B2
优先权日:2010-05-11
标题 :Method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of age-albumin in cells of the mononuclear phagocyte system
发明人：LEE BONG HEE; BYUN KYUNG HEE
权利人:LEE BONG HEE; BYUN KYUNG HEE; GACHON UNIV OF INDUSTRY-ACADEMIC COOP FOUND
摘要:The present invention relates to a method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of AGE-albumin in cells of the mononuclear phagocyte system, to an AGE-albumin synthesis inhibitor, and to a pharmaceutical composition comprising the AGE-albumin synthesis inhibitor for preventing or treating degenerative disease and autoimmune disease. The AGE-albumin of the present invention is synthesized and secreted in human microglia or human macrophages in an Alzheimer's model, stroke model, Parkinson's disease model and rheumatoid arthritis model. The AGE-albumin synthesis and secretion are caused by oxidative stress. The expression of RAGE increases in first-order human neurons or cartilage cells to which AGE-albumin is administered, whereupon a MAPK signaling pathway is activated and the expression of Bax increases to induce an increase in calcium in mitochondria, thus finally inducing cell death. Therefore, the AGE-albumin synthesis inhibitor of the present invention can be valuably used in the diagnosis or treatment of degenerative diseases or autoimmune diseases such as Alzheimer's disease, strokes, Parkinson's disease, amyotrophic lateral sclerosis, rheumatoid arthritis, diabetic retinopathy, AIDS, aging, pulmonary fibrosis, spinal cord injuries, etc.

专利号:US-2023157936-A1
优先权日:2021-11-24
标 题 :Anti-aging skin peel composition and method of application
发明人：ZAHR ALISAR; NGUYEN THU Q; KOCH JOHN; KELLY TATIANA
权利人:JAMRM LLC
摘要:A skincare composition and a method for removing layers of skin in a cosmetic procedure. The skincare composition comprises active ingredients mixed into a cosmetically acceptable carrier. The active ingredients include an effective amount of one or more keratolytic agents for inducing a desired degree of keratolysis in the skin, an effective amount of one or more free radical neutralizing agents for negating cellular damage from reactive chemical species, and an effective amount of one or more agents increasing synthesis of dermal components. The one or more free radical neutralizing agents and the one or more agents increasing synthesis of dermal components are acids in their un-neutralized, natural acid form, and a total amount of the active ingredients is less than 50 w/w% of the skincare composition, and a pH of the skincare composition is between 1.5-3.5.

专利号:US-2006052577-A1
优先权日:2001-02-06
标题:Methods of synthesis of polymers and copolymers from natural products
发明人：SWIFT GRAHAM; WESTMORELAND DAVID G; HUGHES KATHLEEN
权利人:SWIFT GRAHAM; WESTMORELAND DAVID G; HUGHES KATHLEEN
摘要:Described are polymers and copolymers containing sorbitol, citric acid, starch, aspartic acid, succinic anhydride, adipic acid mixtures thereof, methods of their synthesis and their uses.