CAS: 1121-57-9; 1-Cyclohexenylisocyanide

该化合物是一种有机化合物,其特征是附于环己环的异丙氰酸功能组的存在;其分子结构具有六人组成的碳环,一个双环和一个异丙氰酸(-N=C=O)组,该组有助于其反应和有机合成的潜在应用;该化合物一般没有色素,可粉色黄色液体,有独特的味;众所周知,该化合物能够参与各种化学反应,包括核分裂医学添加和循环添加,使其在合成更复杂的分子中具有价值;由于异丙氰酸组的存在,1-异辛烷环己烷还具有毒性,应当按照适当的安全规程加以谨慎处理;其反应和结构特征使其在诸如聚合化学和药用化学等领域具有兴趣,在这些领域,它可以作为制药或专门化学生产的中间体.

结构式图片

相似化合物

873-95-0 1192-88-7 37677-14-8

上下游产品

CAS号40652-40-2 N-(1-环己烯基)甲酰胺 | CAS号1125-02-6 N-(1-Cyan°Cyclo... | CAS号108-94-1 环己酮 | CAS号5496-10-6 1-氨基环己烷甲腈 | CAS号110-83-8 环己烯 | CAS号100-64-1 环己酮肟 | CAS号1199-15-1 Carbamic acid,N... | CAS号175606-32-3 Benzeneacetamid...

合成工艺路线路线简述

    Methyl N-(Trans-2-Iodocyclohexyl)Carbamate置于三氯硅烷,Potassium Tert-Butylate,N,N-二异丙基乙胺体系中,用 四氢呋喃,二氯甲烷 用作溶剂,化学反应 27.0H,反应生成异氰基环己烯
    参考文献:轻松获得乙烯基异氰酸酯的途径
    标题:轻松获得乙烯基异氰酸酯的途径
    摘要:已经开发了一种由烯烃合成乙烯基异氰酸酯的新方法,该方法基于烯烃的碘异氰酸酯化反应,然后转化为β-碘异氰酸酯,随后进行β-消除反应.
    Doi:10.1016/s0040-4039(00)99237-2

    海关参考信息

    专利信息


    专利号:US-2005020616-A1
    优先权日:2003-07-21
    标 题 :Aryl fused azapolycyclic compounds
    发明人:COE JOTHAM W; O'DONNELL CHRISTOPHER J
    权利人:PFIZER
    摘要:This invention is directed to compounds of the formula (I): n n nand their pharmaceutically acceptable salts, wherein R 1 , R 2 , R 3 and Z are as defined herein; intermediates for the synthesis of such compounds, pharmaceutical compositions containing such compounds; and methods of using such compounds in the treatment of neurological and psychological disorders.

    专利号:US-7205300-B2
    优先权日:1997-12-31
    标 题:Aryl fused azapolycyclic compounds
    发明人:COE JOTHAM WADSWORTH; BROOKS PAIGE ROANNE PALMER
    权利人:PFIZER
    摘要:This invention is directed to compounds of the formula (I): n nand their pharmaceutically acceptable salts, wherein R 1 , R 2 , and R 3 are as defined herein; intermediates for the synthesis of such compounds, pharmaceutical compositions containing such compounds; and methods of using such compounds in the treatment of neurological and psychological disorders.

    专利号:US-11767388-B1
    优先权日:2019-09-18
    标 题 :Silicon-functionalized rubber
    发明人:ENSIGN SETH CODY; VIELHABER MARGARET FLOOK; JOHNGRASS JENA LYNN; MA LIQING
    权利人:GOODYEAR TIRE & RUBBER
    摘要:The compatibility between silica fillers and synthetic rubbers which are synthesized utilizing lanthanide-based catalyst systems, such as neodymium catalyst systems can be improved by terminating the polymerization with a vinyl silane terminating agent. In doing so the vinyl silane is allowed to react with the polymer chain ends of the neodymium rubber to functionalize the chain ends of the polymer chains with silicon containing groups. This results in the rubber having better characteristics for utilization in tire rubber formulations, such a tire tread formulations, that exhibit improved wear characteristics and lower rolling resistance. The process for the synthesis of such functionalized polydiene rubber comprises (1) polymerizing a diene monomer in the presence of a lanthanide-based catalyst system, and (2) terminating the polymerization with a vinyl silane terminator. The functionalized polydiene rubber composition made by this method is comprised of a polydiene rubber which is functionalized at its chain ends with a silicon containing group.

    专利号:US-7122534-B2
    优先权日:1998-04-29
    标 题:Aryl fused azapolycyclic compounds
    发明人:COE JOTHAM WADSWORTH
    权利人:PFIZER
    摘要:The present invention relates to compounds of formula (I) n n nand their pharmaceutically acceptable salts, wherein R 1 , R 2 , R 3 and Z are as defined herein, intermediates in the synthesis of such compounds, pharmaceutical compositions containing such compounds and methods of using such compounds in the treatment of neurological and psychological disorders.

    专利号:WO-0002864-A1
    优先权日:1998-07-10
    标题:Precusors for pna-monomers
    发明人:MARTENS JUERGEN; MAISON WOLFGANG; SCHLEMMINGER IMRE; WESTERHOFF OLE; GROEGER HARALD
    权利人:MARTENS JUERGEN; MAISON WOLFGANG; SCHLEMMINGER IMRE; WESTERHOFF OLE; GROEGER HARALD
    摘要:The invention is directed to compounds of formula (I) wherein A, B, D, E, X and Y are defined in the description. These compounds are useful precursors for the synthesis of monomers for Peptide Nucleic Acids (PNA).

    专利号:DE-69522642-T2
    优先权日:1994-05-18
    标 题:HYMENIALDISINE AND ITS DERIVATIVES, METHOD FOR THE PRODUCTION OF INTERMEDIATE PRODUCTS FOR THEIR SYNTHESIS AND Said INTERMEDIATE PRODUCTS
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    主要参考文献

    参考标题:Novel Applications Of Convertible Isonitriles For The Synthesis Of Mono And Bicyclic γ-Lactams Via A Udc Strategy
    作者:Christopher Hulme,Liang Ma,Marie-Pierre Cherrier,Joseph J Romano,George Morton,Celine Duquenne,Joseph Salvino,Richard Labaudiniere |发布日期:2000.3
    摘要:Application Of The So-Called Convertible Isonitriles For The Solution/solid Phase Generation Of γ-Lactam Analogues. Use Of Tethered N-Boc Aldehydes In The Ugi Multi-Component Reaction (Mcr), Followed By Boc Removal And Base Treatment (A '3-Step, 1-Pot Procedure') Affords γ-Lactams In Good Yield. The Udc (Ugi/de-Boc/cyclize) Strategy, Coupled With A Convertible Isonitrile, Is Now Feasible From All Three

    合成参考文献


    摘要:Wessjohann, L. A.; Kaluđerović, G. N.; Neves Filho, R. A. W.; Morejon, M. C.; Lemanski, G.; Ziegler, T., Science of Synthesis: Multicomponent Reactions, (2013) 1, 485.
    摘要:Wessjohann, L. A.; Kaluđerović, G. N.; Neves Filho, R. A. W.; Morejon, M. C.; Lemanski, G.; Ziegler, T., Science of Synthesis: Multicomponent Reactions, (2013) 1, 435.
    摘要:Wessjohann, L. A.; Kaluđerović, G. N.; Neves Filho, R. A. W.; Morejon, M. C.; Lemanski, G.; Ziegler, T., Science of Synthesis: Multicomponent Reactions, (2013) 1, 442.
    摘要:Wessjohann, L. A.; Kaluđerović, G. N.; Neves Filho, R. A. W.; Morejon, M. C.; Lemanski, G.; Ziegler, T., Science of Synthesis: Multicomponent Reactions, (2013) 1, 491.
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