CAS: 111841-85-1; Propan-2-Yl 4-(Methoxymethyl)-6-Phenylmethoxy-9H-Pyrido[3,4-B]Indole-3-Carboxylate

上下游产品

4-(甲氧基甲基)-6-(苯基甲氧基)-9H-吡啶并[3,4-B]吲哚-3-羧酸乙酯盐酸盐 3-Carboethoxy-4-Methoxymethyl-6-Benzyloxy-β-Carboline 83910-44-5
Isopropyl 6-Benzyloxy-4,9-Bis(Methoxymethyl)-9H-Pyrido[3,4-B]Indole-3-Carboxylate

📜5-Benzyloxy-3-Iodo-1-(Methoxymethyl)Indole-2-Methylene-Tertbutylamine置于盐酸,Palladium Diacetate,三正丁胺,三苯基膦体系中,用 N,N-二甲基甲酰胺,异丙醇 用作溶剂,化学反应 24.0H,反应生成阿贝卡尔
参考文献:Synthesis Of β-And γ-Carbolines By The Palladium-Catalyzed Iminoannulation Of Alkynes
标题:Synthesis Of β-And γ-Carbolines By The Palladium-Catalyzed Iminoannulation Of Alkynes
摘要:A Variety Of Substituted Beta-And Gamma-Carbolines Have Been Prepared In Moderate To Excellent Yields By The Palladium-Catalyzed Annulation Of Internal And Terminal Acetylenes By The Tert-Butylimines Of N-Substituted 3-Iodoindole-2-Carboxaldehydes And 2-Haloindole-3-Carboxaldehydes,Respectively. This Annulation Chemistry Is Effective For A Wide Range Of Alkynes,Including Aryl-,Alkyl-,Hydroxymethyl-,Ethoxycarbonyl-,And Trimethylsilyl-Substituted Alkynes. When An Unsymmetrical Internal Alkyne Is Employed,This Method Generally Gives Two Regioisomers. When A Terminal Alkyne Is Employed,Only One Regioisomer Has Been Isolated. This Palladium-Catalyzed Annulation Chemistry Has Also Been Successfully Applied To The Synthesis Of Two Biologically Interesting Beta-Carboline Alkaloids,Zk93423 And Abecarnil (Zk112119).
Doi:10.1021/jo026317U

专利信息

专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.