CAS: 103489-31-2; 3-(4-Azidophenyl)Propionic Acid

该化合物是一种有机化合物,其特点是其芳香功能组和丙基酸混合物,其位置是一联苯环,其代之以Azido组,有助于其反应性及在点击化学和生物合成过程中的潜在应用;氨基苯酸组的存在允许与其他化学物种发生酸性行为和潜在互动;该化合物一般在室温下是一种固体,由于碳本体酸功能,在极地溶剂中可能表现出中等溶性;其氮基组尤其值得注意,因为它能够进行循环反应,使其在合成有机化学和材料科学中具有价值;在处理该化合物时,安全考虑至关重要,因为在一定条件下,氨可敏感和潜在具有爆炸性;

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欧盟法规

ECHA物质C&L通报

上下游产品

3-(4-aminophenyl)propionic acid trans-p-amin°Cinnamic acid 4-nitro-trans-cinnamic acid 4-azidophenylpropanoic acid N-hydroxysuccinimide ester 3-(4-Amino-2-hydroxy-phenyl)-propionic acid methyl ester 3-[2-Hydroxy-4-(trityl-amino)-phenyl]-propionic acid methyl ester 3-[2-(tert-Butyl-dimethyl-silanyloxy)-4-(trityl-amino)-phenyl]-propionic acid methyl ester

合成工艺路线路线简述

  • 合成目标产物 3-(4-Azidophenyl)Propionic Acid 主要起始原料 3-(4-Aminophenyl)Propionic Acid
  • (文献来源)合成步骤主要原料 3-(4-Aminophenyl)Propionic Acid
📜对硝基肉桂酸置于palladium On Activated Charcoal 盐酸,Sodium Azide,氢气,Sodium Nitrite体系中,化学反应生成3-(4-叠氮苯基)丙酸
参考文献:Utilization Of A Nitrenium Ion Cyclization In A Synthesis Of A Photoactive Prostaglandin,17-(4-Azido-2-Hydroxyphenyl)-18,19,20-Trinorprostaglandin F2/ga
标题:Utilization Of A Nitrenium Ion Cyclization In A Synthesis Of A Photoactive Prostaglandin,17-(4-Azido-2-Hydroxyphenyl)-18,19,20-Trinorprostaglandin F2/ga
摘要:
Doi:10.1016/s0040-4039(00)95644-2

海关参考信息

专利信息


专利号:US-2023295613-A1
优先权日:2020-02-14
标 题:Long chain carbon and cyclic amino acids substrates for genetic code reprogramming
发明人:JEWETT MICHAEL C; LEE JOONGOO; MOORE JEFFREY S; SCHWARZ KEVIN J
权利人:UNIV NORTHWESTERN; UNIV ILLINOIS
摘要:Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

专利号:US-11814621-B2
优先权日:2018-06-01
标题 :Expanding the chemical substrates for genetic code reprogramming
发明人:JEWETT MICHAEL CHRISTOPHER; LEE JOONGOO; MOORE JEFFREY S; SCHWIETER KENNETH E; SCHWARZ KEVIN JEROME
权利人:UNIV NORTHWESTERN; UNIV ILLINOIS
摘要:Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.

专利号:WO-2020205584-A1
优先权日:2019-04-02
标 题 :Optimized cell-free synthesis of invasion plasmid antigen b and related compositions and methods of use

专利号:EP-3946443-A1
优先权日:2019-04-02
标 题:Optimized cell-free synthesis of invasion plasmid antigen b and related compositions and methods of use

专利号:US-2022125907-A1
优先权日:2019-04-02
标题 :Optimized cell-free synthesis of invasion plasmid antigen b and related compositions and methods of use

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📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


参考文献:10.1038/s42004-021-00488-0
摘要:Stolz S, Bauer M, Pignedoli CA, Krane N, Bommert M, Turco E, Bassi N, Kinikar A, Merino-Dìez N, Hany R, Brune H, Gröning O, Widmer R. Asymmetric azide-alkyne Huisgen cycloaddition on chiral metal surfaces. Communications Chemistry. 2021 Apr 12;4(1):51. doi: 10.1038/s42004-021-00488-0.
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