📜对硝基肉桂酸置于palladium On Activated Charcoal 盐酸,Sodium Azide,氢气,Sodium Nitrite体系中,化学反应生成3-(4-叠氮苯基)丙酸 参考文献:Utilization Of A Nitrenium Ion Cyclization In A Synthesis Of A Photoactive Prostaglandin,17-(4-Azido-2-Hydroxyphenyl)-18,19,20-Trinorprostaglandin F2/ga 标题:Utilization Of A Nitrenium Ion Cyclization In A Synthesis Of A Photoactive Prostaglandin,17-(4-Azido-2-Hydroxyphenyl)-18,19,20-Trinorprostaglandin F2/ga 摘要: Doi:10.1016/s0040-4039(00)95644-2
专利号:US-2023295613-A1 优先权日:2020-02-14 标 题:Long chain carbon and cyclic amino acids substrates for genetic code reprogramming 发明人:JEWETT MICHAEL C; LEE JOONGOO; MOORE JEFFREY S; SCHWARZ KEVIN J 权利人:UNIV NORTHWESTERN; UNIV ILLINOIS 摘要:Abstract: Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.
专利号:US-11814621-B2 优先权日:2018-06-01 标题 :Expanding the chemical substrates for genetic code reprogramming 发明人:JEWETT MICHAEL CHRISTOPHER; LEE JOONGOO; MOORE JEFFREY S; SCHWIETER KENNETH E; SCHWARZ KEVIN JEROME 权利人:UNIV NORTHWESTERN; UNIV ILLINOIS 摘要:Disclosed are methods, systems, components, and compositions for synthesis of sequence defined polymers. The methods, systems, components, and compositions may be utilized for incorporating novel substrates that include non-standard amino acid monomers and non-amino acid monomers into sequence defined polymers. As disclosed herein, the novel substrates may be utilized for acylation of tRNA via flexizyme catalyzed reactions. The tRNAs thus acylated with the novel substrates may be utilized in synthesis platforms for incorporating the novel substrates into a sequence defined polymer.
专利号:WO-2020205584-A1 优先权日:2019-04-02 标 题 :Optimized cell-free synthesis of invasion plasmid antigen b and related compositions and methods of use
专利号:EP-3946443-A1 优先权日:2019-04-02 标 题:Optimized cell-free synthesis of invasion plasmid antigen b and related compositions and methods of use
专利号:US-2022125907-A1 优先权日:2019-04-02 标题 :Optimized cell-free synthesis of invasion plasmid antigen b and related compositions and methods of use
参考文献:10.1038/s42004-021-00488-0 摘要:Stolz S, Bauer M, Pignedoli CA, Krane N, Bommert M, Turco E, Bassi N, Kinikar A, Merino-Dìez N, Hany R, Brune H, Gröning O, Widmer R. Asymmetric azide-alkyne Huisgen cycloaddition on chiral metal surfaces. Communications Chemistry. 2021 Apr 12;4(1):51. doi: 10.1038/s42004-021-00488-0.