CAS: 87-78-5; Rel-(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-Hexaol

• 英文名称Rel-(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-Hexaol
• 中文名称甘露醇
• IUPAC名称rel-(2R,3R,4R,5R)-Hexane-1,2,3,4,5,6-hexaol
• 其它别名Mannitol; Maitol; Dl-Mannitol; Hexahydroxyhexane; Cordycepin 10% Mannitol; Mannitol Usp; Mannitol Usp/bp; Mannitol Pyrogen Free Usp24
• CAS编号87-78-5
• MFCD编号:MFCD00065361
• EINECS号:201-770-2
• 分子式:C6H14O6
• 分子量:182.17
• 产品CID: 1886462
• 产品分类有机原料→分子砌块→脂肪链类化合物

• 相似结构搜索
• InChIKey: FBPFZTCFMRRESA-KIUGVBIANA-N
• InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1…
• 计算化学: 氢键受体数6.0氢键供体数6.0可旋转键数5.0

相似化合物

物理性质

• 熔点167°C
• 沸点494.9°C
• 闪点290-295°C/3.5mm
• 密度1.596
• pKa:pKa 13.50(H2O,t =18)(Approximate)
• PSA:121.38
• LogP:-3.5854
• 折射率1.5970 (估算)
• 溶解性177.3G/l(25 °c)
• 敏感性A sugar alcohol. More closely related to carbohydrates than to other polyhydric alcohols [Noller]. Flammable and/or toxic gases are generated by the combination with alkali metals, nitrides, strong reducing agents and strong oxidizing agents.
• 外观形态白色至类白色固体
• 储存条件惰性气氛,室温
• 产品应用该化合物用于二尿素或甜食剂.

MSDS等安全信息

• GHS符号GHS07
• 危险类别SYMPTOMS: Symptoms of exposure to this compound include nausea, vomiting, headache, chills, chest pain and pulmonary edema. It may cause irritation of the skin, eyes and respiratory tract. Other symptoms may include lethargy, confusion, heart failure and death. Exposure has caused an electrolyte and fluid imbalance, hypersensitivity reactions, diarrhea, thirst, fever, tachycardia, hyponatremia, urinary retention, dehydration, blurred vision, convulsions, urticaria, hypotension and hypertension. It has also caused hyperglycemia and glycosuria. Coughing may result from inhalation. Ingestion may cause gastric irritation. Skin contact may cause discoloration of sensitive skin. Eye contact may cause redness and pain. Intravenous use has led to blood pressure elevation and bladder tubule changes. | ACUTE/CHRONIC HAZARDS: This compound may cause irritation of the skin, eyes and respiratory tract. When heated to decomposition it emits acrid smoke and toxic fumes of carbon monoxide and carbon dioxide. (NTP, 1992)
• 警示词Warning
• 危险描述H302-H315-H319-H335
• 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
• 安全声明S22,S24/25
• 危险类别码No evidence of teratogenicity in experimental animals; [REPROTOX] No evidence of carcinogenicity in mice or rats; [NTP] May cause irritation; [Sigma-Aldrich MSDS]
• WGK Germany3.0

上下游产品

合成工艺路线路线简述

• 17598-81-1 = 87-78-5 [标题:Reaction Conditions
  标题:Method For The Production Of D-Glucitol Containing Up To 15% By Weight Of D-Mannitol (I.E.,Sorbit M)
  参考文献:Czechoslovakia]
  
  56-81-5 = 87-78-5 + 2152-56-9 + 328-50-7 + 77-92-9 + 149-32-6
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water; 168 H,Ph 5.5,28 °C
  标题:Significant Enhancement Of Citric Acid Production By Yarrowia Lipolytica Immobilized In Bacterial Cellulose-Based Carrier
  作者:Zywicka,Anna; Junka,Adam; Ciecholewska-Jusko,Daria; Migdal,Pawel; Czajkowska,Joanna; Et Al
  参考文献:Journal Of Biotechnology 日期:2020 卷标:321 页码:13-22]
  
  57-50-1 = 87-78-5 + 328-50-7 + 77-92-9 + 149-32-6
  反应条件:1.1R:Naoh,S:H2O,168 H,28°C,Ph 5.5
  标题:Significant Enhancement Of Citric Acid Production By Yarrowia Lipolytica Immobilized In Bacterial Cellulose-Based Carrier
  作者:By Zywicka,Anna Et Al
  参考文献:Journal Of Biotechnology 日期:2020 卷标:321 页码:13-22]
  
  41847-61-4 = 87-78-5 [标题:Reaction Conditions
  标题:Chemoselective Reduction Of D-Fructose In The Presence Of D-Glucose
  作者:Roy,Rene; Gervais,Suzanne; Gamian,Andrzej; Boratynski,Janusz
  参考文献:Carbohydrate Research 日期:1988 卷标:177]
  
  470-23-5 = 87-78-5 [标题:Reaction Conditions
  标题:Process For D-Mannitol Production
  参考文献:Czechoslovakia]
  
  30237-26-4 = 87-78-5 + 26566-34-7
  反应条件:1.1 Reagents: Hydrogen Solvents: Ethanol
  标题:2-Substituted-1,3-Dioxan-5-Ones: Synthesis,Reactions,And Synthetic Applications
  作者:Nowak,Pawel
  参考文献:1998 卷标:59(11)]
  
  9004-34-6 = 87-78-5 + 6920-22-5 + 107-21-1 + 87-99-0 + 111-29-5 + 57-55-6 + 584-03-2 + 50-70-4 + 149-32-6 + 56-81-5
  反应条件:1.1 Catalysts: Nickel; 26 H,11.4 Mpa,190 °C; 8 Mpa1.2 Reagents: Water; Cooled
  标题:Optimisation Of The Processing Conditions Of Hydrolytic Hydrogenation Of Cellulose Using Carbon Nanofiber Supported Ni Catalysts
  作者:Frecha,E.; Remon,J.; Torres,D.; Suelves,I.; Pinilla,J. L.
  参考文献:Catalysis Today 日期:2023 卷标:423

海关参考信息

• 2905122000-异丙醇
  2905310000-1,2-乙二醇
  2905320000-1,2-丙二醇
  2905399001-1,3-丙二醇
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管