CAS: 86-43-1; 2-(Diethylamino)Ethyl 4-Amino-2-Propoxybenzoate

专利信息

专利号:EP-1776333-B1
优先权日:2004-07-21
标 题:Ammonium salts and ammonium salt/mineral salt clathrate compounds for use as vehicle and effective form for pharmaco-medical applications and for use as phase transfer agents for chemical applications
发明人：REUTER UWE; OETTMEIER RALF; KASCH HELMUT
权利人:KASCH HELMUT
摘要:This invention relates to ammonium salts and stable storable ammonium salts and ammonium salt/mineral salt clathrate compounds (inclusion compounds, clusters) having acid dibasic anionic acid residues such as bicarbonate, to methods for producing them and to pharmaco-medical and chemical synthetic applications for said compounds. According to the invention, compounds for pharmaco-medical and chemical synthetic applications are produced which comprise the ammonium salt and ammonium salt/mineral salt clathrate compounds (inclusion compounds, clusters) having acid dibasic anionic acid residues of general formula I with R1, R2, R3 and R4=alkyl and substituted alkyl straight-chain or branched, optionally having an alcohol, ether, silyether, ester, amino or amide function, H or aryl-alkyl, with aryl being an aromatic or heteroaromatic ring having optionally additional substituents, such as alkyl having 1 to 4 C atoms, OH, NR*2 with R*2=O, alkyl with alkyl of between 1 and 4 C atoms or H, COOH, COOR, CN, NO2 and the cationic positive N+ is optionally part of an active agent, Y is a dibasic acid residue of an organic dicarboxylic acid or CO3-, corresponding to HY-=HCO3-, and x=0.5 to 30 represents the number of the mineral salt molecules for clathrate compound formation or 0. In pharmaco-medical applications applies the generalizable effectiveness principle according to which to ammonium salt/mineral salt cluster is used as vehicle and active agent for novel forms of application of nitrogen-containing active agent bases. In chemistry, these agents are used in the synthesis of active agents and valuable products, e.g. of cyclic carbonates.

专利号:US-2024091199-A1
优先权日:2017-06-30
标 题:Deuterated Domperidone Compositions, Methods, and Preparation
发明人：PEARCE CATHERINE; ISAACSOHN JON; PATEL PIYUSH
权利人:CINDOME PHARMA INC
摘要:Deuterated domperidone compositions, methods of synthesis, methods of use, and dosing formulations providing beneficial safety and other effects.

专利号:US-2012232031-A1
优先权日:2009-10-19
标 题:Injectable formulations for intra-articular or peri-articular administration
发明人：HUTCHINSON JOHN HOWARD; PRASIT PETPIBOON PEPPI; DEARMOND ISABELLE MARGUERITE
权利人:HUTCHINSON JOHN HOWARD; PRASIT PETPIBOON PEPPI; DEARMOND ISABELLE MARGUERITE; PANMIRA PHARMACEUTICALS LLC
摘要:Described herein are injectable formulations for intra-articular or peri-articular administration, wherein the formulation is administered to treat joint pain. An injectable formulation for intra-articular or peri-articular administration disclosed herein comprises a therapeutically-effective amount of a leukotriene synthesis inhibitor compound formulated for intra-articular or peri-articular administration.

专利号:US-10590110-B2
优先权日:2016-02-04
标题:Deuterated domperidone compositions, methods, and preparation
发明人：PEARCE CATHERINE; ISAACSOHN JON; PATEL PIYUSH
权利人:CINRX PHARMA LLC; CINDOME PHARMA LLC
摘要:Deuterated domperidone compositions, methods of synthesis, methods of use, and dosing formulations providing beneficial safety and other effects.

专利号:US-11364226-B2
优先权日:2017-06-30
标 题 :Deuterated domperidone compositions, methods, and preparation
发明人：PEARCE CATHERINE; ISAACSOHN JON; PATEL PIYUSH
权利人:CINRX PHARMA LLC
摘要:Deuterated domperidone compositions, methods of synthesis, methods of use, and dosing formulations providing beneficial safety and other effects.

专利号:RU-2417217-C2
优先权日:2004-07-21
标 题 :Salt clusters of ammonium salt and mineral salt with dibasic acid anions which are resistant and stable during storage and synthesis method thereof