61-90-5 + 56-40-6 = 686-50-0 + 869-19-2 反应条件:1.1 Solvents: Water; 22 Mpa,379 °C 标题:Study On Condensation Of Amino Acid In Super Critical Water Fluid 作者:Harada,Osamu; Et Al 参考文献:Hyogo-Kenritsu Kogyo Gijutsu Senta Kenkyu Hokokusho 日期:2003 卷标:12
📜N-(N-Benzyloxycarbonyl-L-Leucyl)-Glycine置于氢溴酸,溶剂黄146体系中,化学反应生成 L-亮氨酰甘氨酸 参考文献:Farrington Et Al.,Journal Of The Chemical Society,1957,P. 1407,1410 标题:Farrington Et Al.,Journal Of The Chemical Society,1957,P. 1407,1410
专利号:WO-9720061-A1 优先权日:1995-11-30 标题:Synthesis of hyaluronic acid 发明人:WONG CHI-HUEY; DELUCA CLAUDIO 权利人:SCRIPPS RESEARCH INST; WONG CHI HUEY; DELUCA CLAUDIO 摘要:A preparative enzymatic synthesis of hyaluronic acid (HA) from UDP-N-acetyl-D-glucosamine (UDP-GlcNAc) and UDP-glucuronic acid (UDP-GlcA) catalyzed by hyaluronic acid synthase is coupled with regeneration of the sugar nucleotides. Polymerizing UDP-GlcA and UDP-GlcNAc to form hyaluronic acid results in the formation of released UDP. The released UDP is, in turn, employed in the regeneration of UDP-GlcA and UDP-GlcNAc. Use of the released UDP for regenerating UDP-GlcA and UDP-GlcNAc prevents a build-up of these compounds and prevents or reduces feed back inhibition of the hyaluronic acid synthase reaction that would otherwise be caused by such build-up. Accordingly, the product yield is enhanced by the recycling of these compounds.
专利号:US-5962294-A 优先权日:1992-03-09 标题 :Compositions and methods for the identification and synthesis of sialyltransferases 发明人:PAULSON JAMES C; WEN XIAOHONG; LIVINGSTON BRIAN; GILLESPIE WILLIAM; KELM SORGE; BURLINGAME ALMA L; MEDZIHRADSZKY KATALIN 权利人:UNIV CALIFORNIA; CYTEL CORP 摘要:DNA isolates coding for sialyltransferase which contain a conserved region of homology and methods of obtaining such DNA are provided, together with expression systems for recombinant production of sialyltransferase.
专利号:EP-2588602-A1 优先权日:2010-07-01 标题:Variants of glucoamylase 发明人:DEGN PETER EDVARD; BOTT RICHARD R; VROEMEN CASPER WILLEM; SCHEFFERS MARTIJN SILVAN; AEHLE WOLFGANG; PETERSEN ELIN 权利人:DUPONT NUTRITION BIOSCI APS; DANISCO US INC 摘要:The present invention relates to combinatorial variants of a parent glucoamylase that have altered properties for reducing the synthesis of condensation products during hydrolysis of starch. Accordingly the variants of a parent glucoamylase are suitable such as for use within brewing and glucose syrup production. Also disclosed are DMA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.
专利号:US-2004171041-A1 优先权日:2001-05-22 标 题 :Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
专利号:WO-9805758-A1 优先权日:1996-08-02 标题 :STRUCTURE AND EXPRESSION OF THE ALPHA-CARBOXYLTRANSFERASE SUBUNIT OF HETEROMERIC-ACETYL-CoA CARBOXYLASE 发明人:OHLROGGE JOHN B; SHORROSH BASIL S 权利人:UNIV MICHIGAN STATE; OHLROGGE JOHN B; SHORROSH BASIL S 摘要:The nucleic acid sequence encoding the alpha-carboxyltransferase (alpha-CT) subunit of acetyl-CoA carboxylase and its deduced amino acid sequence are provided. Vectors comprising the nucleic acid sequence, plant cells transformed with the vectors, as well as plants transformed with the nucleic acid sequence and seeds of the transgenic plant, are also provided. By controlling the expression of the alpha-CT gene, carboxylation of acetyl-CoA can be controlled. Thus, by introducing constructs of the gene of the present invention in sense or antisense orientation, carboxylation of acetyl-CoA to produce malonyl-CoA may be increased or decreased and fatty acid synthesis and elongation in plants and seeds which depend on malonyl-CoA may be controlled. The figure shows ACCase and CT activities and protein profiles.
专利号:WO-9529253-A1 优先权日:1994-04-22 标 题:Dna encoding cephamycin biosynthesis late enzymes 发明人:COQUE JUAN JOSE R; ENGUITA FRANCISCO J; FUENTE JUAN L; LLARENA FRANCISCO J; LIRAS PALOMA; MARTIN JUAN F 权利人:MERCK & CO INC; COQUE JUAN JOSE R; ENGUITA FRANCISCO J; FUENTE JUAN L; LLARENA FRANCISCO J; LIRAS PALOMA; MARTIN JUAN F 摘要:DNA encoding the late enzymes involved in the synthesis of the antibiotic cephamycin have been isolated and purified. The particular enzymes are involved in the late steps of cephamycin biosynthesis. These DNA's have been sequenced and cloned into recombinant expression vectors for their recombinant expression in host cells. The DNA's, vectors containing them and recombinant host cells which express them are useful for the production of antibiotics.
[参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. [参考文献]: Griet Van Zeebroeck, Et Al. Transport And Signaling Via The Amino Acid Binding Site Of The Yeast Gap1 Amino Acid Transceptor. Nat Chem Biol. 2009 Jan;5(1):45-52.
合成参考文献
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