CAS: 686-50-0; L-Leucylglycine

该化合物是一种由氨酸精液和甘油结合结合而成的二极酸,它被归类为非必要的氨酸衍生物,即可以由身体合成.该物质在外表上一般为白色,从白到非白,在水中可溶解,因此在各种生物化学应用中有用.L-Leucylglycine展示了peptides的共同特征,例如参与氢结合和形成次级结构的能力.它在蛋白合成中发挥作用,并能影响代谢过程.此外,它可能具有药物和营养方面的应用,特别是由于存在乳油而导致肌肉恢复和生长的配方,因为其作用在刺激蛋白合成中是众所周知的.化合物的稳定性和再活性可能受到诸如pH和温度等因素的影响,这些因素是其处理和储存的重要考虑因素.

结构式图片

相似化合物

615-82-7 32991-17-6 997-05-7

上下游产品

CAS号26117-20-4 氨基甲酰-L-亮氨酸 | CAS号6000-44-8 甘氨酸钠 | CAS号56-40-6 甘氨酸 | CAS号3190-70-3 (S)-4-异丁基恶唑烷-2,5-二酮 | CAS号2706-38-9 Z-LEU-GLY-OH | CAS号72-18-4 l-缬氨酸 | CAS号7154-27-0 2-[(2-bromo-4-m... | CAS号1738-89-2 Benzyloxycarbon... | CAS号2706-38-9 Z-LEU-GLY-OH

合成工艺路线路线简述

  • 61-90-5 + 56-40-6 = 686-50-0 + 869-19-2
    反应条件:1.1 Solvents: Water; 22 Mpa,379 °C
    标题:Study On Condensation Of Amino Acid In Super Critical Water Fluid
    作者:Harada,Osamu; Et Al
    参考文献:Hyogo-Kenritsu Kogyo Gijutsu Senta Kenkyu Hokokusho 日期:2003 卷标:12
📜N-(N-Benzyloxycarbonyl-L-Leucyl)-Glycine置于氢溴酸,溶剂黄146体系中,化学反应生成 L-亮氨酰甘氨酸
参考文献:Farrington Et Al.,Journal Of The Chemical Society,1957,P. 1407,1410
标题:Farrington Et Al.,Journal Of The Chemical Society,1957,P. 1407,1410

海关参考信息

专利信息


专利号:WO-9720061-A1
优先权日:1995-11-30
标题:Synthesis of hyaluronic acid
发明人:WONG CHI-HUEY; DELUCA CLAUDIO
权利人:SCRIPPS RESEARCH INST; WONG CHI HUEY; DELUCA CLAUDIO
摘要:A preparative enzymatic synthesis of hyaluronic acid (HA) from UDP-N-acetyl-D-glucosamine (UDP-GlcNAc) and UDP-glucuronic acid (UDP-GlcA) catalyzed by hyaluronic acid synthase is coupled with regeneration of the sugar nucleotides. Polymerizing UDP-GlcA and UDP-GlcNAc to form hyaluronic acid results in the formation of released UDP. The released UDP is, in turn, employed in the regeneration of UDP-GlcA and UDP-GlcNAc. Use of the released UDP for regenerating UDP-GlcA and UDP-GlcNAc prevents a build-up of these compounds and prevents or reduces feed back inhibition of the hyaluronic acid synthase reaction that would otherwise be caused by such build-up. Accordingly, the product yield is enhanced by the recycling of these compounds.

专利号:US-5962294-A
优先权日:1992-03-09
标题 :Compositions and methods for the identification and synthesis of sialyltransferases
发明人:PAULSON JAMES C; WEN XIAOHONG; LIVINGSTON BRIAN; GILLESPIE WILLIAM; KELM SORGE; BURLINGAME ALMA L; MEDZIHRADSZKY KATALIN
权利人:UNIV CALIFORNIA; CYTEL CORP
摘要:DNA isolates coding for sialyltransferase which contain a conserved region of homology and methods of obtaining such DNA are provided, together with expression systems for recombinant production of sialyltransferase.

专利号:EP-2588602-A1
优先权日:2010-07-01
标题:Variants of glucoamylase
发明人:DEGN PETER EDVARD; BOTT RICHARD R; VROEMEN CASPER WILLEM; SCHEFFERS MARTIJN SILVAN; AEHLE WOLFGANG; PETERSEN ELIN
权利人:DUPONT NUTRITION BIOSCI APS; DANISCO US INC
摘要:The present invention relates to combinatorial variants of a parent glucoamylase that have altered properties for reducing the synthesis of condensation products during hydrolysis of starch. Accordingly the variants of a parent glucoamylase are suitable such as for use within brewing and glucose syrup production. Also disclosed are DMA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.

专利号:US-2004171041-A1
优先权日:2001-05-22
标 题 :Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences

专利号:WO-9805758-A1
优先权日:1996-08-02
标题 :STRUCTURE AND EXPRESSION OF THE ALPHA-CARBOXYLTRANSFERASE SUBUNIT OF HETEROMERIC-ACETYL-CoA CARBOXYLASE
发明人:OHLROGGE JOHN B; SHORROSH BASIL S
权利人:UNIV MICHIGAN STATE; OHLROGGE JOHN B; SHORROSH BASIL S
摘要:The nucleic acid sequence encoding the alpha-carboxyltransferase (alpha-CT) subunit of acetyl-CoA carboxylase and its deduced amino acid sequence are provided. Vectors comprising the nucleic acid sequence, plant cells transformed with the vectors, as well as plants transformed with the nucleic acid sequence and seeds of the transgenic plant, are also provided. By controlling the expression of the alpha-CT gene, carboxylation of acetyl-CoA can be controlled. Thus, by introducing constructs of the gene of the present invention in sense or antisense orientation, carboxylation of acetyl-CoA to produce malonyl-CoA may be increased or decreased and fatty acid synthesis and elongation in plants and seeds which depend on malonyl-CoA may be controlled. The figure shows ACCase and CT activities and protein profiles.

专利号:WO-9529253-A1
优先权日:1994-04-22
标 题:Dna encoding cephamycin biosynthesis late enzymes
发明人:COQUE JUAN JOSE R; ENGUITA FRANCISCO J; FUENTE JUAN L; LLARENA FRANCISCO J; LIRAS PALOMA; MARTIN JUAN F
权利人:MERCK & CO INC; COQUE JUAN JOSE R; ENGUITA FRANCISCO J; FUENTE JUAN L; LLARENA FRANCISCO J; LIRAS PALOMA; MARTIN JUAN F
摘要:DNA encoding the late enzymes involved in the synthesis of the antibiotic cephamycin have been isolated and purified. The particular enzymes are involved in the late steps of cephamycin biosynthesis. These DNA's have been sequenced and cloned into recombinant expression vectors for their recombinant expression in host cells. The DNA's, vectors containing them and recombinant host cells which express them are useful for the production of antibiotics.

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

[参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.
[参考文献]: Griet Van Zeebroeck, Et Al. Transport And Signaling Via The Amino Acid Binding Site Of The Yeast Gap1 Amino Acid Transceptor. Nat Chem Biol. 2009 Jan;5(1):45-52.

合成参考文献


摘要:S. P. Datta, R. Leberman, and B. R. Rabin. Trans. Faraday Soc. 55, 1982 (1959).
摘要:P. H. Mitchell and J. P. Greenstein. J. Gen. Physiol. 14, 255 (1930).
摘要:M. J. Johnson and W. H. Peterson. J. Biol. Chem. 112, 25 (1935).
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