CAS: 54322-65-5; Cyclopropylacetyl Chloride

相似化合物

4023-34-1 30923-69-4 38674-38-3

上下游产品

Cyclopropylmethanol sodium cyanide cyclopropylacetic acid 2-cyclopropylacetonitrile3-cyclopropanepropionic acid 2-cyclopropyl-N-phenylacetamide methyl cyclopropylacetate N-Methyl-N-phenylcyclopropylacetamide

📜环丙乙酸置于草酰氯,N,N-二甲基甲酰胺体系中,用 二氯甲烷 作为反应溶剂,化学反应生成 环丙烷乙酰氯
参考文献:利用负载型金纳米粒子作为单电子转移催化剂进行脱羧交叉偶联
标题:利用负载型金纳米粒子作为单电子转移催化剂进行脱羧交叉偶联
摘要:介绍 负载型金纳米颗粒 (Au Nps) 在多种化学反应中表现出优异的催化活性,例如低温下一氧化碳1-4和氨5-7的氧化以及水煤气变换反应.8-14它们的特性还使得有机分子能够进行非均相还原和氧化转化以获得精细化学品.15-25同时,主要基于电子顺磁共振(epr)光谱的详细研究揭示了金纳米颗粒与有机自由基之间的谐波相互作用.26-33这些发现使我们重新考虑 Au Np 影响下的几种催化有机转化是否可能包括单电子转移.另一方面,过渡金属,光激发金属配合物和无机半导体促进的单电子转移是产生有机自由基的最有力的工具之一.特别是,光氧化还原催化下自由基交叉偶联反应的最新进展使化学家能够合成多样化且复杂的分子.34-44最近,我们发现在负载型 Au Nps 催化剂存在下,稳定的 C(Sp 3)−o 键发生均裂,实现自由基烷基-甲硅烷基交叉偶联,得到烷基硅烷(方案 1).45,46乙硅烷的单电子氧化引发了
DOI:10.1002/adsc.202300462

专利信息

专利号:US-6413957-B1
优先权日:1998-04-21
标题:Methods of inhibiting cell proliferation using indeno [1,2-c]pyrazol-4-ones
发明人：NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; YUE EDDY W
权利人:BRISTOL MYERS SUIBB PHARMA COM
摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I): n that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-7 and their regulatory subunits know as cyclins A-G. This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

专利号:US-7250435-B2
优先权日:1999-10-20
标 题:Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
发明人：NUGIEL DAVID A; CARINI DAVID J; DI MEO SUSAN V; VIDWANS ANUP P; YUE EDDY
权利人:BRISTOL MYERS SQUIBB PHARMA CO
摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I): n nthat are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-7 and their regulatory subunits know as cyclins A-G.n n This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

专利号:US-2009118296-A1
优先权日:2005-07-20
标 题:Heteroaromatic Compounds As Inhibitors Of Stearoyl-Coenzyme A Delta-9 Desaturase
发明人：BLACK CAMERON; DESCHENES DENIS; GAGNON MARC; LACHANCE NICOLAS; LEBLANC YVES; LEGER SERGE; LI CHUN SING; OBALLA RENATA M
权利人:MERCK FROSST CANADA LTD
摘要:Heteroaromatic compounds of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease; atherosclerosis; lipid disorders; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and fatty liver disease.

专利号:US-6593356-B2
优先权日:1999-10-20
标 题 :Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
发明人：NUGIEL DAVID; CARINI DAVID; DIMEO SUSAN; VIDWANS ANUP; YUE EDDY
权利人:BRISTOL MYERS SQUIBB PHARMA CO
摘要:The present invention relates to the synthesis of a new class of indeno[1,2-c]pyrazol-4-ones of formula (I):that are potent inhibitors of the class of enzymes known as cyclin dependent kinases, which relate to the catalytic subunits cdk1-7 and their regulatory subunits know as cyclins A-G.This invention also provides a novel method of treating cancer or other proliferative diseases by administering a therapeutically effective amount of one of these compounds or a pharmaceutically acceptable salt form thereof. Alternatively, one can treat cancer or other proliferative diseases by administering a therapeutically effective combination of one of the compounds of the present invention and one or more other known anti-cancer or anti-proliferative agents.

专利号:US-4093622-A
优先权日:1975-05-19
标题 :Pyridine esters of cyclopropane-carboxylic acid
发明人：HENRICK CLIVE A; STAAL GERARDUS B
权利人:ZOECON CORP
摘要:Heterocyclic organic esters and thioesters characterized by the presence of one or two cyclopropane moieties, synthesis thereof, and compositions thereof for the control of mites and ticks.

专利号:US-3876682-A
优先权日:1973-06-04
标题 :Substituted benzoates of cyclpropane carboxylic acids
发明人：HENRICK CLIVE A; STALL GERARDUS B
权利人:HENRICK CLIVE A; STALL GERARDUS B
摘要:Organic esters characterized by the presence of a cyclopropane moiety, synthesis thereof, and compositions thereof for the control of mites and ticks.