CAS: 486-28-2; 6-Hydroxy-5,7-Dimethoxy-2H-Chromen-2-One

该化合物是附于苯环的氢氧基组,该组具有苯化合物的典型特征,增强了其再活性和与其他生物分子的相互作用;Fraxinol在有机溶剂中可溶性,但水溶性有限,影响其生物利用率和在各个领域的应用,包括制药和天然产品化学;此外,对Fraxinol的潜在治疗应用的研究仍在继续,特别是在其对细胞过程的影响和传统医学的作用方面.

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CAS号105827-22-3 3,6-dihydroxy-2... | CAS号88140-31-2 6-Formyllimetin | CAS号88140-32-3 2-(5,7-dimethox... | CAS号28752-90-1 acetyl fraxinol | CAS号487-06-9 柠檬油素 | CAS号32451-87-9 mandshurin | CAS号55085-47-7 5,6,7-三甲氧基香豆素

合成工艺路线路线简述

    📜5,7-二甲氧基香豆素置于sodium Hydroxide体系中,化学反应生成 白蜡树精
    参考文献:Bhavsar; Desai,Indian Journal Of Pharmacy,1951,Vol. 13,P. 200,203
    标题:Bhavsar; Desai,Indian Journal Of Pharmacy,1951,Vol. 13,P. 200,203

    海关参考信息

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    1. Spath, E., and Jerzmanowska-Sienkiewiczowa, Z. Natural coumarins. XXV. Fraxinol, a new constituent of the bark of the ash. Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen 70B, 698-702 (1937). 2. Kolodziej, H., Kayser, O., Woerdenbag, H.J., et al. Structure-cytotoxicity relationships of a series of natural and semi-synthetic simple coumarins as assessed in two human tumour cell lines. Z. Naturforsch. C 52(3-4), 240-244 (1997). 3. Khadzhai, Y.I. Effect of coumarin, flavonoid, and khellin derivatives on the soporific effect of barbiturates. Farmakologiya i Toksikologiya (Kiev) 7, 46-48 (1972).

    合成参考文献


    参考文献:10.1016/s0031-9422(98)00097-1
    摘要:Iossifova T, Vogler B, Kostova I. Secoiridoid glucosides from fraxinus ornus bark. Phytochemistry. 1998 Nov;49(5):1329–32. doi: 10.1016/s0031-9422(98)00097-1.
    参考文献:10.1007/978-3-030-28940-9_62
    摘要:Bussmann RW, Batsatsashvili K, Kikvidze Z, Paniagua-Zambrana NY, Khutsishvili M, Maisaia I, Sikharulidze S, Tchelidze D. Fraxinus excelsior L. Oleaceae. 2020. In: Ethnobotany of Mountain Regions.
    参考文献:10.1002/jccs.200700169
    摘要:Hu H, Jian Y, Cao H, Zheng X. Phenolic Compounds from Elsholtzia Bodinieri Van't. J Chinese Chemical Soc. 2007 Oct;54(5):1189–94. doi: 10.1002/jccs.200700169.
    参考文献:10.1248/cpb.33.4069
    摘要:TSUKAMOTO H, HISADA S, NISHIBE S. Coumarins from bark of Fraxinus japonica and F. mandshurica var. japonica. Chem. Pharm. Bull. 1985;33(9):4069–73. doi: 10.1248/cpb.33.4069.
    参考文献:10.1007/978-3-662-64800-1_6
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