CAS: 22601-59-8; Baciguent
该化合物是源于Bacillus Subtilis var.Tracy的聚苯酯抗生素,通过抑制细胞壁合成,对抗模性细菌表现出强大的抗菌活动;技术级配方适合工业应用,包括研究,制药中间体和抗微生物剂开发;其稳定性,高纯度和一贯性能使它成为大规模工艺的可靠选择;A型乙酸酯因其在受控制条件下抑制细菌生长的效力而特别受到重视,以确保在试验和生产环境中可再生;该产品有详细的技术规格,以满足专门应用的严格质量要求.
- 英文名称Baciguent
- 中文名称杆菌肽A
- IUPAC名称(4R)-4-[[(2S)-2-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carbonyl]amino]-4-methylpentanoyl]amino]-5-[[(2S,3S)-1-[[(6R,9S,15S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclopentacos-21-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-oxopentanoic acid
- 其它别名BacitracinA (8CI); Bacitracin F,1-[N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucine]-; 1,4,7,10,13,16,19-Heptaazacyclopentacosane, cyclic peptide deriv.; BacitracinA2a; L-Asparagine,N-[[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-a-glutamyl-L-isoleucyl-L-lysyl-D-ornithyl-L-isoleucyl-D-phenylalanyl-L-histidyl-D-a-aspartyl-, (10®4)-lactam
- CAS编号22601-59-8
- MFCD编号:MFCD00143642
- EINECS号:245-115-9
- 分子式:C66H103N17O16S分子量:1422.7
- 产品CID: 1164260
- 产品分类分析化学 → 标准品 → 食品和饮料标准品
物理性质
MSDS等安全信息
欧盟法规
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海关参考信息
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专利信息
专利号:WO-9747313-A1
优先权日:1996-06-10
标题:Total synthesis of bacitracin polypetides
发明人：GRIFFIN JOHN H; MCDOUGAL PATRICK G
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Methods for the total synthesis of bacitracin-type polypeptides are described, as well as useful analogs of bacitracin A, and treatment of bacterial infection using such analogs.
专利号:US-5662898-A
优先权日:1990-08-20
标 题 :Genes for the synthesis of antipathogenic substances
发明人：LIGON JAMES M; HILL DWIGHT STEVEN; LAM STEPHEN TING; HAMMER PHILIP E
权利人:CIBA GEIGY CORP
摘要:The present invention is directed to the production of an antipathogenic substance (APS) in a host via recombinant expression of the polypeptides needed to biologically synthesize the APS. Genes encoding polypeptides necessary to produce particular antipathogenic substances are provided, along with methods for identifying and isolating genes needed to recombinantly biosynthesize any desired APS. The cloned genes may be transformed and expressed in a desired host organisms to produce the APS according to the invention for a variety of purposes, including protecting the host from a pathogen, developing the host as a biocontrol agent, and producing large, uniform amounts of the APS.
专利号:US-5912151-A
优先权日:1987-04-14
标题 :Preparation of xanthan gum
发明人：POLLOCK THOMAS J; THORNE LINDA
权利人:SHINETSU CHEMICAL CO; SHINETSU BIO INC
摘要:A method of increasing xanthan gum production, comprising culturing a Xanthomonas campestris strain having a xanthan-increasing modification in a culture medium, wherein the modification is selected from the group consisting of (1) a mutation causing rifampicin-resistance; (2) a mutation causing bacitracin-resistance; or (3) exogenous genetic information controlling the synthesis of xanthan; and separating xanthan from the culture medium, is provided along with specific DNA sequences and Xanthomonas campestris strains showing increased xanthan gum production.
专利号:US-5340743-A
优先权日:1987-04-14
标题 :Xanthan gum-producing strain of xanthomonas
发明人：POLLOCK THOMAS J; THORNE LINDA
权利人:SHINETSU CHEMICAL CO; SHINETSU BIO INC
摘要:A method of increasing xanthan gum production, comprising culturing a Xanthomonas campestris strain having a xanthan-increasing modification in a culture medium, wherein the modification is selected from the group consisting of (1) a mutation causing rifampicin-resistance; (2) a mutation causing bacitracin-resistance; or (3) exogenous genetic information controlling the synthesis of xanthan; and separating xanthan from the culture medium, is provided along with specific DNA sequences and Xanthomonas campestris strains showing increased xanthan gum production.
专利号:US-5472870-A
优先权日:1987-04-14
标 题 :Biologically pure culture of a strain of Xanthomonas compestris ATCC 55429
发明人：POLLOCK THOMAS J; THORNE LINDA
权利人:SHINETSU CHEMICAL CO; SHINETSU BIO INC
摘要:A method of increasing xanthan gum production, comprising culturing a Xanthomonas campestris strain having a xanthan-increasing modification in a culture medium, wherein the modification is selected from the group consisting of (1) a mutation causing rifampicin-resistance; (2) a mutation causing bacitracin-resistance; or (3) exogenous genetic information controlling the synthesis of xanthan; and separating xanthan from the culture medium, is provided along with specific DNA sequences and Xanthomonas campestris strains showing increased xanthan gum production. The strain is preferably ATCC 55429.
专利号:US-5338841-A
优先权日:1987-04-14
标 题:DNA segments controlling production of xanthan gum
发明人：POLLOCK THOMAS J; THORNE LINDA
权利人:SHINETSU CHEMICAL CO; SHINETSU BIO INC
摘要:A method of increasing xanthan gum production, comprising culturing a Xanthomonas campestris strain having a xanthan-increasing modification in a culture medium, wherein the modification is selected from the group consisting of (1) a mutation causing rifampicinresistance; (2) a mutation causing bacitracin-resistance; or (3) exogenous genetic information controlling the synthesis of xanthan; and separating xanthan from the culture medium, is provided along with specific DNA sequences and Xanthomonas campestris strains showing increased xanthan gum production.
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品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.5281/zenodo.5794106
摘要:The LOTUS Initiative for Open Natural Products Research: frozen dataset union wikidata (with metadata) | DOI:10.5281/zenodo.5794106
参考文献:10.1128/aac.00474-11
摘要:Ramón-García S, Ng C, Anderson H, Chao JD, Zheng X, Pfeifer T, Av-Gay Y, Roberge M, Thompson CJ. Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen. Antimicrob Agents Chemother. 2011 Aug;55(8):3861–9.
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