CAS: 1693-74-9; Tetrahydrofuran-D8

该化合物是一种四氢呋喃的分解形式,是一种循环醚,通常用作有机化学的溶剂."d8"表示分子含有8个原子,即氢的同位素.这种替代加强了其在NMR光谱学中的用途,由于氢信号产生的背景噪音减少,可以进行更清晰的光谱分析.THF-d8是一种无色,挥发性液体,具有一种与醚相似的特质.它与水和许多有机溶剂不相适应,使它成为多种化学反应和工艺的多用途溶剂.除化器的存在还改变了某些物理特性,例如沸点和熔点,与非受污染的对口相比.THF-d8主要用于研究环境,特别是涉及反应机制,动能和有机化合物的结构分析的研究.同任何化学物质一样,适当的处理和安全防范措施由于其易燃性和潜在健康危害至关重要.

结构式图片

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CAS号109-99-9 四氢呋喃 | CAS号30994-23-1 琥珀酸二甲酯-2,2,3,3-d4 | CAS号100-41-4 乙苯 | CAS号17988-51-1 (3-ethylphenyl)... | CAS号17988-50-0 (4-ethylphenyl)... | CAS号81632-00-0 (butan-2-yl-3,3... | CAS号81631-56-3 trimethyl((5-ph... | CAS号81631-55-2 5-phenylhexan-1... | CAS号104-51-8 丁基苯 | CAS号3360-41-6 4-苯基-1-丁醇 | CAS号81631-80-3 trimethyl(4-phe...

合成工艺路线路线简述

  • 合成目标产物 Tetrahydrofuran-D8 主要起始原料 Tetrahydrofuran
  • (文献来源)合成步骤主要原料 Tetrahydrofuran
丁二酸二甲酯-D4置于lithium Aluminium Deuteride,乙醚体系中,化学反应生成氘代四氢呋喃
参考文献:Fluorine-Containing Nitrogen Compounds. I. Trifluoroethylamines
标题:Fluorine-Containing Nitrogen Compounds. I. Trifluoroethylamines
摘要:
Doi:10.1021/jo01091A024

海关参考信息

专利信息


专利号:US-10889599-B2
优先权日:2018-02-27
标 题:1,1-diborylalkyl-1-metal compounds, preparation method thereof, and their applications toward synthesis of 1,1-diboronate ester compounds
发明人:CHO SEUNG HWAN; LEE YEOSAN
权利人:POSTECH ACAD IND FOUND
摘要:The present invention relates to a 1,1-diborylalkyl-1-metal compound including one metal group together with two identical boron groups at the sp3 carbon center, and its use. Specifically, the present invention relates to development of novel organic reactions, synthesis of functional molecules, and synthesis of new drugs by applying the novel 1,1-diboryl-1-metal substituted alkyl compounds to various molecular libraries which could not be synthesized by conventional methodologies.

专利号:US-12338202-B2
优先权日:2021-09-10
标 题 :One pot synthesis of urea (meth)acrylates
发明人:BESTGEN SEBASTIAN; BEYER SILVIA
权利人:EVONIK OPERATIONS GMBH
摘要:A one-pot synthesis of polymerizable and acyclic urea (meth)acrylates, preferably mono(meth)acrylates, can be performed via in-situ synthesis of urea alcohols or amines followed by direct reaction with a (meth)acrylate reactive diluent. The urea alcohol/amine is obtained from isocyanates and alcohols, amines, or hydroxyamines. Subsequently, the reaction with the (meth)acrylate reactive diluent takes place and the urea (meth)acrylate is directly obtained either in solution with the reactive diluent, or as a pure material after removal of the reactive diluent.

专利号:WO-2023152730-A1
优先权日:2022-02-14
标题 :Amine-borane adducts in the synthesis of polyester and its copolymers using cyclic esters and compositions thereof
发明人:FENG XIAOSHUANG; LIU JINGJING; GNANOU YVES
权利人:UNIV KING ABDULLAH SCI & TECH
摘要:Embodiments of the present disclosure provide for the process of synthesis of polyester and its copolymers through (co)polymerization of cyclic esters and with other oxygenated monomers using amine-borane adduct. Embodiments of the present disclosure further describe the controlled anionic ring-opening polymerization of the cyclic compounds. Embodiments of the present disclosure also describe the polymerization of cyclic compounds using the synergistic effect of amines and thioureas. Embodiments of the present disclosure also describe compositions of polymers formed by the said process.

专利号:US-10730904-B2
优先权日:2012-11-14
标 题:Method for liquid-phase synthesis of nucleic acid
发明人:NONOGAWA MITSURU; NAGATA TOSHIAKI; SAITO HIDEKI; YASUMA TSUNEO
权利人:TAKEDA PHARMACEUTICALS CO
摘要:In this method, an oligonucleotide represented by formula (II) [wherein Y 1 , Q, Base, r and r′ are each as defined in claim 1 ] is prepared by using, as a synthesis unit, a novel nucleoside monomer compound represented by formula (I) [wherein X, R 1 , Y, Base, Z, Ar, R 2 , R 3 and n are each as defined in claim 1 ]. The novel nucleoside monomer compound is a nucleoside, the base moiety of which is substituted with an aromatic-hydrocarbon-ring-carbonyl or -thiocarbonyl group having at least one hydrophobic group. The method can dispense with column-chromatographic purification in every reaction, and enables base elongation not only in the 3′-direction but also in the 5′-direction, thus attaining efficient liquid-phase mass synthesis of an oligonucleotide.

专利号:US-8618281-B2
优先权日:2006-01-03
标 题 :Geometric synthesis of porphyrin rods
发明人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D
权利人:LINDSEY JONATHAN S; YU LIANHE; THAMYONGKIT PATCHANITA; BHISE ANIL D; UNIV NORTH CAROLINA STATE
摘要:A method of making a compound of Formula I′ n ncomprises reacting a compound of the formula DLCHO, with a compound of the formulan n nto produce the compound of Formula I′. Methods of using the compounds are also described, particularly as intermediates for the synthesis of porphyrin rods, which porphyrin rods are in turn useful for (among other things) the production of molecular memory devices.

专利号:US-6603070-B2
优先权日:2000-07-21
标题 :Convergent synthesis of multiporphyrin light-harvesting rods
发明人:LINDSEY JONATHAN S; LOEWE ROBERT S
权利人:UNIV NORTH CAROLINA STATE
摘要:The present invention provides a convergent method for the synthesis of light harvesting rods. The rods are oligomers of the formula A 1 (A b+1 ) b , wherein b is at least 1, A 1 through A b+1 are covalently coupled rod segments, and each rod segment A 1 through A 1+b comprises a compound of the formula X 1 (X m+1 ) m wherein m is at least 1 and X 1 through X m+1 are covalently coupled porphyrinic macrocycles. Light harvesting arrays and solar cells containing such light harvesting rods are also described, along with intermediates useful in such methods and rods produced by such methods.
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合成参考文献


摘要:Waldvogel, S. R.; Welschoff, N., Science of Synthesis, (2010) 45, 1170.
摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1305.
摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1287.
摘要:Batrice, R. J.; Karmel, I.-S. R.; Eisen, M. S., Science of Synthesis Knowledge Updates, (2012) 4, 121.
摘要:Vrána, J.; Růžička, A., Science of Synthesis Knowledge Updates, (2021) 2, 38.
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