CAS: 13368-42-8; N-(Trimethylsilyl)Morpholine

相似化合物

42185-06-8 27550-90-9 1005-67-0

上下游产品

morpholine N,O-bis-(trimethylsilyl)-acetamide E-1-morpholino-1-phenyl-2-trimethylsilylethene bis(trimethylsilyl) 2-(2-furyl)ethylphosphonite S-morpholin-4-yl-thiooxime2,2,2-trifluoro-1-phenyl-ethanone S-morpholin-4-yl-thiooxime N-(toluene-4-sulfonyl)-morpholine-4-sulfinimidic acid diethylamideN-(toluene-4-sulfonyl)-morpholine-4-sulfinimidic acid diethylamide 4-sulfanediyl)-bis-morpholine4,4'-(benzoylimino-λ4-sulfanediyl)-bis-morpholine N-(4-chloro-benzoyl)-morpholine-4-sulfinimidoyl chlorideN-(4-chloro-benzoyl)-morpholine-4-sulfinimidoyl chloride

📜E-1-Morpholino-1-Phenyl-2-Trimethylsilylethene置于吗啉体系中,化学反应 19.0H,以25%的收率获得n-(三甲基硅基)吗啉
参考文献:Synthesis And Properties Of Some β-Triorganosilylenamines
标题:Synthesis And Properties Of Some β-Triorganosilylenamines
摘要:
Doi:10.1016/s0022-328X(00)81002-5

专利信息

专利号:EP-0901500-B1
优先权日:1996-05-03
标题:In situ preparation of nucleoside phosphoramidites and their use in synthesis of oligonucleotides
发明人：ZHANG ZHAODA; TANG JIN-YAN
权利人:AVECIA BIOTECHNOLOGY INC
摘要:The invention provides novel bifunctional phosphitylating reagents and their application in in situ preparation of 5'-protected nucleoside phosphoramidites and synthesis of oligonucleotides. Bifunctional phosphitylating reagents according to the invention react quickly with nucleosides under weakly acidic conditions. In addition, the bifunctional phosphitylating reagents according to the invention generate chemoselectively the corresponding nucleoside phosphoramidites in situ, without need to purify the nucleoside phosphoramidites before using them in oligonucleotide synthesis. Finally, the bifunctional phosphitylating reagents according to the invention are relatively stable and easy to handle.

专利号:US-10173993-B2
优先权日:2015-12-09
标题 :Process for the synthesis of sulfones and sulfonamides
发明人：VON WOLFF NIKLAS; CHAR JOËLLE; CANTAT THIBAULT
权利人:COMMISSARIAT ENERGIE ATOMIQUE
摘要:A one pot single step process is described for the synthesis of a compound, including a labeled compound, containing a sulfonyl functional group comprising the step of mixing together a silane, an SO 2 source, an electrophilic compound, an activating compound and optionally a metal catalyst. A process for producing tracers from a labeled sulfonyl containing compound prepared by the described process is also included.

专利号:US-6340749-B1
优先权日:1995-10-06
标题:Preparation of nucleoside phosphoramidites and oligonucleotide synthesis
发明人：ZHANG ZHAODA; TANG JIN-YAN
权利人:AVECIA BIOTECHNOLOGY INC
摘要:The invention provides novel bifunctional phosphitylating reagents and their application in in situ preparation of 5'-protected nucleoside phosphoramidites and synthesis of oligonucleotides. Bifunctional phosphitylating reagents according to the invention react quickly with nucleosides under neutral or weakly basic conditions, without an additional activation step. In addition, the bifunctional phosphitylating reagents according to the invention generate chemoselectively the corresponding nucleoside phosphoramidites in situ, without need to purify the nucleoside phosphoramidites before using them in oligonucleotide synthesis. Finally, the bifunctional phosphitylating reagents according to the invention are relatively stable and easy to handle.

专利号:WO-9742208-A1
优先权日:1996-05-03
标题 :In situ preparation of nucleoside phosphoramidites and their use in synthesis of oligonucleotides

专利号:EP-0901500-A1
优先权日:1996-05-03
标 题:$i(IN SITU) PREPARATION OF NUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE IN SYNTHESIS OF OLIGONUCLEOTIDES

专利号:US-2017166542-A1
优先权日:2015-12-09
标 题:Process for the Synthesis of Sulfones and Sulfonamides