CAS: 13364-32-4; N-[(2-Chlorophenyl)Methyl]-1-Phenylpropan-2-Amine

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欧盟法规

REACH注册ECHA物质REACH预注册

合成工艺路线路线简述

    📜非那明,2-氯苯甲醛,硼氢化钠 以83%的收率获得
    参考文献:Noggle,F. T. (Jr;),Clark C. Randall;Andurkar,Shridhar V.;Deruiter,Jac+,J. Liquid Cromatogr.,13,(1990) N,C. 763-77
    标题:Noggle,F. T. (Jr;),Clark C. Randall;Andurkar,Shridhar V.;Deruiter,Jac+,J. Liquid Cromatogr.,13,(1990) N,C. 763-77

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    专利信息


    专利号:US-11717498-B2
    优先权日:2013-12-31
    标题 :Methods of treatment using amphetamine controlled release, prodrug, and abuse deterrent dosage forms
    发明人:POPP KARL; MECKLER HAROLD
    权利人:Chemapotheca LLC; PHARMAPOTHECA A INC
    摘要:The invention also relates to pharmaceutical compositions comprising highly pure amphetamine and amphetamine-class compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds, and to methods of manufacturing, delivering, and using the amphetamine compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds.

    专利号:US-2025223262-A1
    优先权日:2022-03-31
    标 题 :Synthesis of morphinans with reduced herg activity and mop binding
    发明人:LAMMERT ECKHARD; SCHOLZ OKKA; OTTER SILKE; HEREBIAN DIRAN; HOFFMANN TORSTEN; SANZ MIGUEL ANGEL; KRAMP LAURENZ; LEVY LAURA MARIANA; HRISTEVA STANIMIRA
    权利人:HEINRICH HEINE UNIV DUESSELDORF; DEUTSCHE DIABETES FORSCHUNGSGESELLSCHAFT E V; TAROS CHEMICALS GMBH & CO KG
    摘要:The invention relates to morphinan-derivatives, processes for their preparation, medicaments containing them and the use of these morphinan-derivatives for the preparation of medicaments.

    专利号:US-12208068-B2
    优先权日:2013-12-31
    标题:Amphetamine controlled release, prodrug, and abuse-deterrent dosage forms
    发明人:POPP KARL; MECKLER HAROLD
    权利人:PHARMAPOTHECA A INC
    摘要:The invention also relates to processes for producing abuse deterrent pharmaceutical compositions comprising highly pure amphetamine and amphetamine-class compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds, and to methods of manufacturing, delivering, and using the amphetamine compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds.

    专利号:US-8598153-B2
    优先权日:2006-09-22
    标题 :Method of treatment using fatty acid synthesis inhibitors
    发明人:SINGH SHEO B; TOTA MICHAEL R; WANG JUN
    权利人:SINGH SHEO B; TOTA MICHAEL R; WANG JUN; MERCK SHARP & DOHME
    摘要:The present invention relates to natural products that possess fatty acid synthesis inhibitor activity and can be used to treat and prevent diseases such as obesity, cancer, diabetes, fungal infections, Mycobacterium tuberculosis infections, malarial infections and other apicomplexan protozoal diseases.

    专利号:US-2025213502-A1
    优先权日:2016-02-24
    标 题 :Amphetamine Controlled Release, Prodrug, and Abuse-deterrent Dosage Forms
    发明人:POPP KARL; MECKLER HAROLD
    权利人:PHARMAPOTHECA A INC
    摘要:The invention also relates to pharmaceutical compositions comprising highly pure amphetamine and amphetamine-class compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds, and to methods of manufacturing, delivering, and using the amphetamine compounds resulting from the synthesis of chiral and racemic amphetamine derivatives by stereospecific, regioselective cuprate addition reaction with aziridine phosphoramidate compounds.

    专利号:EP-4499223-A1
    优先权日:2022-03-31
    标 题 :Synthesis of morphinans with reduced herg activity and mop binding

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664
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