CAS: 83-56-7; Naphthalene-1,5-Diol

• 英文名称Naphthalene-1,5-Diol
• 中文名称1,5-二羟基萘
• IUPAC名称naphthalene-1,5-diol
• 其它别名1,5-Dihydroxynaphthalene; Naphthalene-1,5-diol; 1,5-Naphthalenediol
• CAS编号83-56-7
• MFCD编号:MFCD00003980
• EINECS号:201-487-4
• FDA UNII编号:P25HC23VH6
• 分子式:C10H8O2
• 分子量:160.17
• 产品CID: 1824300
• 产品分类有机原料 → 烃类化合物及其衍生物 → 芳香烃

• 相似结构搜索
• InChIKey: BOKGTLAJQHTOKE-UHFFFAOYSA-N
• InChI=1S/C10H8O2/c11-9-5-1-3-7-8(9)4-2-6-10(7)12/h1-6,11-12H…
• 计算化学: 氢键受体数2.0氢键供体数2.0可旋转键数0.0

物理性质

• 熔点259-261 °C
• 沸点375.4±15.0 °C at 760 mmHg
• 闪点193.5±15.0 °C
• 密度1.3±0.1 g/cm3
• PH:6 (0.5g/l, H2O, 20°C)
• pKa:9.28±0.40(预测)
• PSA:40.46
• LogP:1.96
• 折射率1.726
• 蒸汽压0.0±0.9 mmHg at 25°C
• 溶解性0.6G/l
• 外观形态浅米色至极深棕色固体
• 储存条件惰性气氛,室温
• 产品应用用于有机合成,染料中间体,医药中间体,照相工业.
• 性质描述白色针状结晶.熔点265°C.溶于醚和丙酮,微溶于醇和乙酸,难溶于水,不溶于苯和石油醚.碱性溶液在空气中转为棕色.质量标准:外观:灰白色或灰棕色粉末纯度:≥98含量:≥95熔点:≥256°C(偶合法)不溶物:≤0.3水份:≤1.0

MSDS等安全信息

• GHS象形图
• GHS符号GHS07 & GHS09;
  注释: Exclamation mark & Environment
• 危险类别严重眼刺激 类别2
  皮肤致敏 类别1B
  水生慢性毒性 类别2
  急性毒性 类别4(经口)
  特定目标器官毒性 - 单次接触 类别3
  皮肤腐蚀/刺激 类别2
  皮肤致敏 类别1
• 警示词Warning(警告)
• 危险描述H319 |造成严重眼刺激.
  H317 |可能引起皮肤过敏反应.
  H411 |对水生生物有毒并具有长期持续影响.
  H302 |吞咽有害.
  H335 |可能引起呼吸道刺激.
  H315 |造成皮肤刺激.
• 防范说明P264-P270-P280-P301+P312-P305+P351+P338-P337+P313
• UN编号NONH for all modes of transport
• 危险品标志Xn,N,Xi
• 安全声明22-24/25-61-39-29-26
• 危险类别码22-51/53-36-36/37/38
• WGK Germany2

欧盟法规

上下游产品

合成工艺路线路线简述

• 90-15-3 = 83-56-7
  反应条件:1.1 Catalysts: Pseudomonas Fluorescens
  标题:Synthesis Of Dihydroxynaphthalene Isomers By Microbial Oxidation Of 1- And 2-Naphthol
  作者:Bianchi,D.; Et Al
  参考文献:Applied Microbiology And Biotechnology 日期:1997 卷标:48(3) 页码:363-366]
  
  90-15-3 = 83-56-7
  反应条件:1.1 Reagents: Hydrofluoric Acid,Hydrogen Peroxide,Antimony Pentafluoride
  标题:Hydroxylation Of Naphthols In A Superacid Medium
  作者:Jacquesy,Jean Claude; Et Al
  参考文献:Tetrahedron Letters 日期:1983 卷标:24(30) 页码:3099-102]
  
  = 83-56-7 [标题:Reaction Conditions
  标题:Alternating Copolymers Consisting Of Dialkoxylated Naphthalene Along With Either Dithiophenylated 1,4-Dioxopyrrolo-[3,4C]-Pyrrole Or 5H-Thieno[3,4-C]Pyrrole-4,6-Dione: Synthesis And Photo-Electrochemical Properties
  作者:Lim,Young Lae; Et Al
  参考文献:Bulletin Of The Korean Chemical Society 日期:2013 卷标:34(1) 页码:313-316]
  
  = 83-56-7
  反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Ethanol; 50 °C
  标题:Substituted 9-Diethylaminobenzo[a]Phenoxazin-5-Ones (Nile Red Analogues): Synthesis And Photophysical Properties
  作者:Hornum,Mick; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2021 卷标:86(2) 页码:1471-1488]
  
  = 83-56-7
  反应条件:1.1 Reagents: Sulfuric Acid2.1 Reagents: Sodium Dichromate
  标题:Comparative Characterization Of Methods For Production Of Juglone Taking Into Account Environmental Factors
  作者:Kavtaradze,Nino A.; Et Al
  参考文献:Sakartvelos Mecnierebata Akademiis Macne 日期:2008 卷标:34(4) 页码:446-452]
  
  16919-18-9 = 83-56-7 + 16919-18-9
  反应条件:1.1 Solvents: Nitromethane-D3; Rt
  标题:[2]Catenanes And Inclusion Complexes Derived From Self-Assembled Rectangular Pdii And Ptii Metallocycles
  作者:Alvarino,Cristina; Et Al
  参考文献:Dalton Transactions 日期:2012 卷标:41(39) 页码:11992-11998]
  
  1655-29-4 = 83-56-7
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water; 280 °C; Cooled1.2 Reagents: Hydrochloric Acid Solvents: Water; Ph 3,Cooled
  标题:Synthesis Of Levobunolol Hydrochloride
  作者:Lu,Lu; Et Al
  参考文献:Zhongguo Yaowu Huaxue Zazhi 日期:2010 卷标:20(1) 页码:32-35]
  
  1655-29-4 = 83-56-7
  反应条件:1.1 Reagents: Sodium Hydroxide1.2 Acidified
  标题:Optimal Design Of Neutralization Process In 1,5-Dihydroxynaphthalene Production With Solubility Difference Of Naphthalene-1,5-Disulfonic Acid And Naphthalene-1,5-Disulfonic Acid Disodium In Aqueous Sulfuric Acid Solutions
  作者:Xu,Yong-Sheng; Et Al
  参考文献:Industrial & Engineering Chemistry Research 日期:2018 卷标:57(34) 页码:11826-11832]
  
  81-04-9 = 83-56-7
  反应条件:1.1 Reagents: Sodium Hydroxide Solvents: Water; Rt -> 270 °C; 270 °C -> 295 °C; 1.7 Mpa,295 °C; 4 H,295 °C; 295 °C -> 270 °C
  标题:Synthesis Of High-Purity 1,5-Dihydroxynaphthalene
  作者:Meng,Ming-Yang; Et Al
  参考文献:Jingxi Yu Zhuanyong Huaxuepin 日期:2007 卷标:15(7) 页码:17-18]
  
  83-56-7 = 83-56-7
  反应条件:1.1 Reagents: 8-Hydroxyquinoline,Uranyl Nitrate Solvents: Ethanol,Water; Rt1.2 Reagents: Sodium Hydroxide Solvents: Water; Ph 3 - 4.5,Rt
  标题:Microbial Screening Of Thorium(Iv) And Dioxouranium(Vi) Chelates With Oxine And Phenols
  作者:Kapadia,M. A.; Et Al
  参考文献:Journal Of The Indian Chemical Society 日期:2007 卷标:84(7) 页码:637-639]
  
  15013-16-8 = 83-56-7
  反应条件:1.1 Reagents: Dimethyl Sulfate,Sodium Hydroxide,Sodium Dithionite Solvents: Diethyl Ether,Water; Overnight,5 °C1.2 Reagents: N-Bromosuccinimide Solvents: Acetonitrile; Overnight,-10 °C1.3 Reagents: Sodium Methoxide Catalysts: Cuprous Iodide Solvents: Methanol,Dimethylformamide; 48 H,Reflux1.4 Reagents: Ceric Ammonium Nitrate Solvents: Acetonitrile,Dichloromethane; 5 °C
  标题:Discovery Of Juglone And Its Derivatives As Potent Sars-Cov-2 Main Proteinase Inhibitors
  作者:Cui,Jiahua; Et Al
  参考文献:European Journal Of Medicinal Chemistry 日期:2021 卷标:225]
  
  28315-93-7 = 83-56-7
  反应条件:1.1 Reagents: Potassium Carbonate Catalysts: Tetrakis(Triphenylphosphine)Palladium Solvents: Dimethylacetamide; 165 °C
  标题:Substituted 9-Diethylaminobenzo[a]Phenoxazin-5-Ones (Nile Red Analogues): Synthesis And Photophysical Properties
  作者:Hornum,Mick; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2021 卷标:86(2) 页码:1471-1488]
  
  10075-68-0 = 83-56-7
  反应条件:1.1 Reagents: Ceric Ammonium Nitrate Solvents: Acetonitrile,Dichloromethane,Water; 0 °C; 5 °C2.1 Reagents: Dimethyl Sulfate,Sodium Hydroxide,Sodium Dithionite Solvents: Diethyl Ether,Water; Overnight,5 °C2.2 Reagents: N-Bromosuccinimide Solvents: Acetonitrile; Overnight,-10 °C2.3 Reagents: Sodium Methoxide Catalysts: Cuprous Iodide Solvents: Methanol,Dimethylformamide; 48 H,Reflux2.4 Reagents: Ceric Ammonium Nitrate Solvents: Acetonitrile,Dichloromethane; 5 °C
  标题:Discovery Of Juglone And Its Derivatives As Potent Sars-Cov-2 Main Proteinase Inhibitors
  作者:Cui,Jiahua; Et Al
  参考文献:European Journal Of Medicinal Chemistry 日期:2021 卷标:225]
  
  = 83-56-7
  反应条件:1.1 Solvents: Tetrahydrofuran2.1 Reagents: Hydrochloric Acid Solvents: Ethanol; 50 °C
  标题:Substituted 9-Diethylaminobenzo[a]Phenoxazin-5-Ones (Nile Red Analogues): Synthesis And Photophysical Properties
  作者:Hornum,Mick; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2021 卷标:86(2) 页码:1471-1488]
  
  10075-63-5 = 83-56-7 + 3588-80-5
  反应条件:1.1 Reagents: Iodocyclohexane Solvents: N-Methyl-2-Pyrrolidone; 2.5 H,Reflux; Cooled
  标题:An Efficient Method For Demethylation Of Aryl Methyl Ethers
  作者:Zuo,Li; Et Al
  参考文献:Tetrahedron Letters 日期:2008 卷标:49(25) 页码:4054-4056]
  
  = 83-56-7 + 16919-18-9
  反应条件:1.1 Reagents: Potassium Hexafluorophosphate; Rt2.1 Solvents: Nitromethane-D3; Rt
  标题:[2]Catenanes And Inclusion Complexes Derived From Self-Assembled Rectangular Pdii And Ptii Metallocycles
  作者:Alvarino,Cristina; Et Al
  参考文献:Dalton Transactions 日期:2012 卷标:41(39) 页码:11992-11998]
  
  90-15-3 = 83-56-7 + 524-42-5 + 130-15-4 + 132-86-5 + 575-44-0 + 575-38-2 + 569-42-6
  反应条件:1.1 Reagents: Water,Potassium Ferricyanide; Rt
  标题:Oh Radical As A Probe Of The Spin Polarizability In 1- And 2-Naphthol
  作者:Albarran,Guadalupe; Et Al
  参考文献:Journal Of Physical Chemistry A 日期:2018 卷标:122(16) 页码:4015-4022

海关参考信息

• 2902902000-精萘
  2908199090-其他酚的卤化衍生物
  2908999090-其他酚的硝化衍生物
  2918290000-其他含酚基羧酸
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

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• ➥ 象形图和危险代码
• ➥ 防范代码详解
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