CAS: 532-76-3; Hexylcaine Hydrochloride
- 英文名称Hexylcaine Hydrochloride
- 中文名称海克卡因盐酸盐
- IUPAC名称(2-(Benzoyloxy)propyl)cyclohexylammonium chloride
- 其它别名2-Propanol,1-(cyclohexylamino)-, benzoate (ester), hydr°Chloride (8CI,9CI); 2-Propanol,1-(cyclohexylamino)-, benzoate, hydr°Chloride (7CI); 1-Cyclohexylamino-2-propylbenzoate hydr°Chloride; Cyclaine; Cyclaine hydr°Chloride; Hexylcainehydr°Chloride
- CAS编号532-76-3
- MFCD编号:MFCD01697129
- EINECS号:208-544-2
- FDA UNII编号:V00NQ7SDYI
- 分子式:C16H24ClNO2分子量:297.82026
- 产品CID: 1517780
- 产品分类有机原料 → 苯类化合物 → 苯和取代衍生物
物理性质
MSDS等安全信息
合成工艺路线路线简述
📜1-环己基氨基-2-丙醇,苯甲酰氯置于盐酸体系中,化学反应生成 海克卡因盐酸盐
参考文献:Us2486374
标题:Us2486374
海关参考信息
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专利信息
专利号:US-7993390-B2
优先权日:2002-02-08
标 题:Implantable or insertable medical device resistant to microbial growth and biofilm formation
发明人：MILLER KATHLEEN M; BUCAY-COUTO WEENNA; LI JIANMIN
权利人:BOSTON SCIENT SCIMED INC
摘要:Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and/or a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.
供应商参考报价(招募中)
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主要参考文献
1: RUBEN JE, ANDERSON E. Hexylcaine hydrochloride; a preliminary report of its clinical use in comparison with procaine. Am J Surg. 1949 Dec;78(6):843-6. doi: 10.1016/0002-9610(49)90229-9. 6(2):e03440. doi: 10.1016/j.heliyon.2020.e03440.
3: ANDERSON E, RUBEN JE. Clinical use of cyclaine (hexylcaine hydrochloride) for spinal and regional nerve block: report of 2000 cases. Anesthesiology. 1952 Jul;13(4):429-34. doi: 10.1097/00000542-195207000-00012. 14(1):46-52. doi: 10.1097/00000542-195301000-00008.
21:323-8. 155(10):908-9. 58(3):216-20. doi: 10.1097/00000542-198303000-00002. a preliminary report. J Am Vet Med Assoc. 1952 Feb;120(899):71-2. 36(1):120-1.
合成参考文献
摘要:Oyo Yakuri. Pharmacometrics., 5(683), 1971
摘要:Compilation of LD50 Values of New Drugs.
摘要:Journal of Pharmacology and Experimental Therapeutics., 93(388), 1948
摘要:Handbook of Analytical Toxicology, Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969, -(57), 1969
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