CAS: 152-62-5; (8S,9R,10S,13S,14S,17S)-17-Acetyl-10,13-Dimethyl-1,2,8,9,10,11,12,13,14,15,16,17-Dodecahydro-3H-Cyclopenta[a]Phenanthren-3-One

上下游产品

7-Dehydro-9β,10α-progesteron 9-pregnen-5,20-dionDes-A-17α-Δ9-pregnen-5,20-dion (9β,10α)-pregn-4-ene-3,20-dione Progesterone9β,10α-Pregna-4,6,8(14)-trien-3,20-dion

黄体酮置于chromium(Vi) Oxide,盐酸,甲醇,Sodium Tetrahydroborate,Sodium Periodate,Rhodium(III) Chloride Hydrate,硫酸,Rh/al2O3,氢气,四氯苯醌,2,3-二氯-5,6-二氰基-1,4-苯醌,Sodium Hydroxide体系中,用 四氯化碳,乙醇,水,丙酮,甲苯,乙腈,叔丁醇 用作溶剂,化学反应 1.5H,反应生成去氢孕酮
参考文献: Process For Preparation Of Dydrogesterone[fr] Procédé De Préparation Du Dydrogestérone
标题: Process For Preparation Of Dydrogesterone[fr] Procédé De Préparation Du Dydrogestérone
摘要:本发明涉及一种制备去甲孕酮的方法.

专利信息

专利号:US-10189765-B2
优先权日:2015-10-30
标 题:Process for the preparation of 17β-hydroxy-des-A-androst-9,10-en-5-one
发明人：LENNA ROBERTO; DI BRISCO ROBERTO
权利人:IND CHIMICA SRL
摘要:The present invention relates to a new process for the synthesis of 17β-hydroxy-des-A-androst-9,10-en-5-one, the compound of the following formula (1), which can be used as an intermediate in the synthesis of retroprogesterones.

专利号:US-7126014-B2
优先权日:2000-09-05
标题 :Synthesis of epecatechin-4α, 8-epicatechin and -catechin dimers and derivatives thereof
发明人：KOZIKOWSKI ALAN P; ROMANCZYK JR LEO J; TUECKMANTEL WERNER
权利人:MARS INC
摘要:Oligomeric procyanidins containing 4α-linked epicatechin units are rare in nature and have hitherto not been accessible through stereoselective synthesis. Provided herein is the preparation of the prototypical dimer, epicatechin-4α,8-epicatechin, by reaction of the protected 4-ketones with aryllithium reagents derived by halogen/metal exchange from the aryl bromides. Removal of the 4-hydroxyl group from the resulting tertiary benzylic alcohols is effected by tri-n-butyltin hydride and trifluoroacetic acid in a completely stereoselective manner, resulting in hydride delivery exclusively from the β face.

专利号:US-2025289827-A1
优先权日:2022-12-02
标 题:Morphic forms of a mutant braf degrader and methods of manufacture thereof
发明人：YU ROBERT T; HE MINSHENG; SCHNADERBECK MATTHEW J; KREGER BRIDGET; POLLOCK ROY MACFARLANE; JIANG SIYI; LI MEIQI; CHEN BOLU; LU JIANNAN
权利人:C4 THERAPEUTICS INC
摘要:Advantageous isolated morphic forms of (3R)-3-[6-[2-cyano-3-[[ethyl(methyl)sulfamoyl]amino]-6-fluorophenoxy]-4-oxoquinazolin-3-yl]-8-[2-[1-[3-(2,4-dioxo-1,3-diazinan-1-yl)-5-fluoro-1-methylindazol-6-yl]-4-hydroxypiperidin-4-yl]acetyl]-1-oxa-8-azaspiro[4.5]decane (Compound 1), which is a mutant BRAF degrader, and methods to prepare Compound 1 morphic forms for therapeutic applications are provided in the invention. The invention also provides improved methods for the synthesis of Compound 1, new pharmaceutical compositions comprising Compound 1, and new uses of Compound 1.

专利号:US-10654885-B2
优先权日:2017-01-18
标题:Process for the preparation of 9 beta,10 alpha-progesterone (retroprogesterone)
发明人：LENNA ROBERTO; DELFRATE CLAUDIO; RIGAMONTI DAVIDE
权利人:IND CHIMICA SRL; IND CHIMCA S R L
摘要:The present invention refers to a new process for the synthesis of (9β,10α)-pregn-4-ene-3,20-dione, commonly known as retroprogesterone, having the formula (1) shown below.

专利号:US-4525255-A
优先权日:1982-11-16
标 题:Photochemical reactions for commercial synthesis
发明人：GUILLET JAMES E
权利人:GUILLET JAMES E
摘要:Photochemical reactions are conducted using floating polymer beads on the surface of a moving body of water. The polymer bead is impregnated with a reactant, floated on the water in direct sunlight so as to expose the reactant to solar radiation, collected at a downstream location, treated to remove product from the polymer, and then the bead can be recycled. The process can be used to collect and store solar energy in chemical form, or for conducting photochemical synthesis to produce useful chemical products.

专利号:US-4609444-A
优先权日:1982-11-16
标题 :Photochemical reactions for commercial synthesis
发明人：GUILLET JAMES E
权利人:SOLARCHEM CORP
摘要:Photochemical reactions are conducted using polymer beads arranged as a monolayer, e.g. floating on the surface of a moving body of water. The polymer bead is impregnated with a reactant, floated on the water or otherwise exposed as a monolayer in direct sunlight so as to expose the reactant to solar radiation, collected at a downstream location, treated to remove product from the polymer, and then the bead can be recycled. The process can be used to collect and store solar energy in chemical form, or for conducting photochemical synthesis to produce useful chemical products.