📜甲茚置于sodium Periodate,四氧化锇,Phosphate Buffer,Ammonium Acetate体系中,化学反应生成4-甲基异喹啉 参考文献:Synthesis Of Isoquinolines From Indenes 标题:Synthesis Of Isoquinolines From Indenes 摘要: Doi:10.1021/jo00337A036
专利号:US-6472534-B2 优先权日:1999-10-21 标 题:Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors 发明人:BORER BENNETT C; ZOOK SCOTT E; BUSSE JULIETTE K 权利人:AGOURON PHARMA 摘要:Methods for the preparation of chemical intermediates in the synthesis of HIV-protease inhibitors related to and including nelfinavir mesylate are disclosed. The method of this invention comprises converting tetrohydran derivatives into oxazolines to provide key reaction intermediates for the preparation of nelfinavir. Also disclosed is a method for the preparation of a chiral amino alcohol from an epoxy-tetrahydrofuran.
专利号:US-3919155-A 优先权日:1970-12-18 标题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia 发明人:SQUIRE EDWARD NOONAN 权利人:DU PONT 摘要:An improved process for producing an aromatic amine is provided in which an aromatic compound is reacted with ammonia in the presence of a conditioned nickel/nickel oxide cataloreactant at a temperature of from about 150*C. to about 500*C. and at a pressure of from about 10 to about 1000 atmospheres and in the presence of from 1 mole percent to 250 mole percent of water based on the molar amount of the aromatic compound.
专利号:US-3929889-A 优先权日:1971-02-16 标 题 :Synthesis of aromatic amines by reaction of aromatic compounds with ammonia 发明人:SQUIRE EDWARD NOONAN 权利人:DU PONT 摘要:An improved process for producing an aromatic amine is provided in which an aromatic compound is reacted with ammonia in the presence of a conditioned nickel/nickel oxide cataloreactant at a temperature of from about 150*C. to about 500*C. and at a pressure of from about 10 to about 1000 atmospheres.
专利号:US-2002038033-A1 优先权日:1999-10-21 标题:Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors
专利号:US-2003023092-A1 优先权日:1999-10-21 标题 :Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors
专利号:US-6403799-B1 优先权日:1999-10-21 标题:Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors