CAS: 1196-39-0; 4-Methylisoquinoline

该化合物是一种环状结构,包括苯环和环的引信结构,具有环状环状体特征的环状有机化合物,是异丙醇的衍生物,其甲基组群附于异丙醇框架的第四位置,该化合物一般呈现无色的黄色液体或固体,视其纯度和形态而定,无色无色可粉黄,因其芳香性特性而可表现出荧光性.4-甲基乙基索基尼因线在乙醇和乙醚等有机溶剂中可溶解,但水溶性有限,经常用于有机合成,并可作为制药和农用化学品开发的建筑块.此外,该化合物还可能参与各种化学反应,包括电益替代和循环.与许多含氮的乙型循环一样,它可能展示生物活动,从而引起对药用化学的兴趣.适当的处理和安全防范对于其潜在毒性和再活性至关重要.

结构式图片

MSDS等安全信息

    上下游产品

    4-methyl-3,4-dihydro-isoquinoline 4-bromoisoquinoline methyl magnesium iodide formaldehyd 4-methyl-1,2,3,4-tetrahydro-isoquinoline 5-bromo-4-methylisoquinoline 4-methyl-1,2,3,4-tetrahydroisoquinoline hydr°Chloride 1-chloro-4-methylisoquinoline

    合成工艺路线路线简述

      📜甲茚置于sodium Periodate,四氧化锇,Phosphate Buffer,Ammonium Acetate体系中,化学反应生成4-甲基异喹啉
      参考文献:Synthesis Of Isoquinolines From Indenes
      标题:Synthesis Of Isoquinolines From Indenes
      摘要:
      Doi:10.1021/jo00337A036

      海关参考信息

      专利信息


      专利号:US-6472534-B2
      优先权日:1999-10-21
      标 题:Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors
      发明人:BORER BENNETT C; ZOOK SCOTT E; BUSSE JULIETTE K
      权利人:AGOURON PHARMA
      摘要:Methods for the preparation of chemical intermediates in the synthesis of HIV-protease inhibitors related to and including nelfinavir mesylate are disclosed. The method of this invention comprises converting tetrohydran derivatives into oxazolines to provide key reaction intermediates for the preparation of nelfinavir. Also disclosed is a method for the preparation of a chiral amino alcohol from an epoxy-tetrahydrofuran.

      专利号:US-3919155-A
      优先权日:1970-12-18
      标题:Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
      发明人:SQUIRE EDWARD NOONAN
      权利人:DU PONT
      摘要:An improved process for producing an aromatic amine is provided in which an aromatic compound is reacted with ammonia in the presence of a conditioned nickel/nickel oxide cataloreactant at a temperature of from about 150*C. to about 500*C. and at a pressure of from about 10 to about 1000 atmospheres and in the presence of from 1 mole percent to 250 mole percent of water based on the molar amount of the aromatic compound.

      专利号:US-3929889-A
      优先权日:1971-02-16
      标 题 :Synthesis of aromatic amines by reaction of aromatic compounds with ammonia
      发明人:SQUIRE EDWARD NOONAN
      权利人:DU PONT
      摘要:An improved process for producing an aromatic amine is provided in which an aromatic compound is reacted with ammonia in the presence of a conditioned nickel/nickel oxide cataloreactant at a temperature of from about 150*C. to about 500*C. and at a pressure of from about 10 to about 1000 atmospheres.

      专利号:US-2002038033-A1
      优先权日:1999-10-21
      标题:Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors

      专利号:US-2003023092-A1
      优先权日:1999-10-21
      标题 :Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors

      专利号:US-6403799-B1
      优先权日:1999-10-21
      标题:Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors

      供应商参考报价(招募中)

      品牌试剂参考报价(招募中)

      📌 第三方产品分析报告

      ✅ COA系统入驻 | 共享模式

      合成参考文献


      摘要:Wang, X.; Lu, X., Science of Synthesis: DNA-Encoded Libraries, (2024) nan, 243.
      摘要:Granados, A.; Molander, G. A., Science of Synthesis: DNA-Encoded Libraries, (2024) nan, 293.
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