CAS: 108-28-1; Protoanemonene

该化合物是一种循环化合物,其特点是五点方位有甲苯组的柔性环状结构,该化合物是呋喃的衍生物,具有独特的芳香和脂质特性,典型的色色无色黄色液体,有独特的香味,经常被称为甜味或焦糖味.该物质在有机溶剂中溶解,水溶性有限.该物质的分子结构有助于其再活动,使其成为有机合成的潜在中间体,并成为口味和香味化学中感兴趣的一个主题.此外,5-甲基五-五H-呋喃-2-1可以参与各种化学反应,包括电益替代和聚合过程.安全数据表明,应谨慎处理该物质,因为它在接触时可能构成健康风险.

结构式图片

上下游产品

5-(acetyloxy)-5-methyl-2(5H)-furanone t-en-4-ynoic acidpent-2t-en-4-ynoic acid 4-oxo-2-pentenoic acid 2-methylfuran valeric acid 5-ethyl-2(3H)-furanone γ-phenylthiomethyl-α,β-butenolide diphenyldisulfane

合成工艺路线路线简述

  • 合成目标产物 5-Methylenefuran-2(5H)-One 主要起始原料 2(5H)-Furanone, 5-Hydroxy-5-Methyl-
  • (文献来源)合成步骤主要原料 2(5H)-Furanone, 5-Hydroxy-5-Methyl-
📜1-β-Alanino-1-Deoxy-D-Fructose 反应 0.25H,反应生成原白头翁素
参考文献:Thermal Analysis Of 1-Deoxy-1-Glycino-D-Fructose And 1-β-Alanino-1-Deoxy-D-Fructose
标题:Thermal Analysis Of 1-Deoxy-1-Glycino-D-Fructose And 1-β-Alanino-1-Deoxy-D-Fructose
摘要:
Doi:10.1016/s0008-6215(00)84539-5

专利信息


专利号:US-2005215772-A1
优先权日:2002-08-19
标 题:Furanone derivatives and methods of making same
发明人:KUMAR NARESH
权利人:KUMAR NARESH
摘要:Novel synthesis methods, to the products of such novel methods, and to uses of these products. In particular, the present invention provides methods for the reactions of furanones, in particular fimbrolides, with amines. The invention has particular application in the synthesis of halogenated 1,5-dihydro-pyrrol-2-one, 5-halomethylene substituted 1,5-dihydropyrrol-2-ones (lactam analogues of fimbriolides), 5-amino substituted furanones and 5-aminomethylene-2(5H)-furanones and their synthetic analogues. The invention also relates to novel compounds and uses thereof.

专利号:US-7495129-B2
优先权日:2003-01-13
标题:Purification of a monomer by extraction with a phase former and crystallization
发明人:BALDUF TORSTEN; NORDHOFF STEFAN; YU-CHIANG DENNIS THONG; KOBUS AXEL; ROOS MARTIN
权利人:EVONIK STOCKHAUSEN GMBH
摘要:The invention concerns a process for purification of an acidic monomer having a double bond, as well as a device for synthesis of an acidic monomer having a double bond, a process for producing an acidic monomer having a double bond, an acid monomer having a double bond and obtainable by this process, fibers, formed bodies, films, foams, superabsorbent polymers and other special polymers based on or containing this acidic monomer, the use of this acidic monomer in or for producing fibers, formed bodies, films, foams, superabsorbent polymers or other special polymers.

专利号:US-6958145-B2
优先权日:2000-06-28
标 题:Synthesis of cyclic compounds
发明人:KUMAR NARESH; READ ROGER WAYNE
权利人:UNISEARCH LTD
摘要:A method for the preparation of a compound of formula (II) wherein R 1 and R 2 are independently H, alkyl, alkoxy, oxoalkyl, alkenyl, aryl or arylalkyl whether unsubstituted or substituted, optionally interrupted by one or more hetero atoms, straight chain or branched chain, hydrophilic, hydrophobic or fluorophilic; R 3 , R 4 , R 5 and R 6 are independently or all hydrogen or halogen; provided that at least two of the R 3 , R 4 , R 5 and R 6 are halogens.

专利号:US-10781157-B2
优先权日:2016-12-08
标题:Process for preventing the deposition of polymers in a process for purifying (meth)acrylic acid
发明人:CABON YVES; TRAGUS CHRISTIAN
权利人:ARKEMA FRANCE
摘要:This invention produces technical (meth)acrylic acid without being confronted with problems of fouling of systems to purify the crude reaction mixture of (meth)acrylic acid synthesis, due to the presence of glyoxal formed during synthesis. The invention is based on the addition or generation of quinoline derivative in a glyoxal-containing (meth)acrylic acid flow in a quinoline/glyoxal derivative molar ratio ranging from 0.1 to 5, during the purification steps, said quinoline compound with one of formulas (I) or (II): n nwherein, groups R 1 , R 2 , R 3 , and R 4 independently denote a hydrogen atom or a C 1 -C 6 , or R 1 et R 2 C-alkyl group combine and together with the atoms to which they are attached, form a saturated or unsaturated ring or heterocycle, preferably a phenyl group, and/or R 3 and R 4 combine and with the atoms to which they are attached, form a saturated or unsaturated ring or heterocycle, preferably a phenyl group.

专利号:US-4214092-A
优先权日:1979-02-21
标题:Rearrangement of acyloxy furans and thiophenes prepared from butenolides
发明人:KRAUS GEORGE A
权利人:UNIV IOWA STATE RES FOUND INC
摘要:A method of preparing acyloxy furans and thiophenes from butenolides comprising reacting a pre-selected butenolide with an acylating agent in the presence of a base to provide an acyloxy furan intermediate, which in turn undergoes rearrangement in the presence of Lewis Acids by cleavage of a carbon-oxygen bond, and addition of the cleaved moiety to the furan ring forming a carbon-carbon bond on the ring. The result is a heretofore unknown group of lactone type compounds which are biologically active, in and of themselves, and in addition offer use as versatile synthesis intermediates to achieve, by conventional synthesis methods heretofore unavailable compounds.

专利号:US-7935774-B2
优先权日:2007-01-24
标 题 :Particulate water-absorbent polymer and production method thereof
发明人:IKEUCHI HIROYUKI; NAGASAWA MAKOTO
权利人:NIPPON CATALYTIC CHEM IND
摘要:An object of the present invention is to provide a method for producing a particulate water-absorbent polymer particle having remarkably improved long-term color stability, without an adverse effect (such as a delay in polymerization) on synthesis of the particulate water-absorbent polymer. The method includes the steps of polymerizing a monomer aqueous solution (B) containing (i) at least one type of monomer (A) that is capable of forming a particulate water-absorbent polymer by polymerization, (ii) at least one type of crosslinking agent, (iii) at least one type of polymerization initiator and (iv) an organophosphorus compound in an amount of not less than 1 but not more than 100 ppm by mass with respect to the monomer (A) so as to form a hydrogel polymer, and drying the hydrogel polymer. The method enables to provide an excellent particulate water-absorbent polymer that realizes (i) long-term color stability and improvement in urine tolerance and (ii) absorbing property, which are in such a trade-off relationship. In this way, the above object is attained.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Studies On Structurally Simple α,β-Butenolides. Iii.
作者:P. Camps,J. Cardellach,J. Corbera,J. Font,R.M. Ortuño,O. Ponsatí |发布日期:1983.1
摘要:The Reactivity Of The Title Compounds With Different Nucleophiles Has Been Checked And It Was Shown That Products From Reaction With Sodium Phenylthiolate Result From An Elimination-Addition Process In Which Protoanemonin Is The Key Intermediate. The Synthesis Of (−)-(R)-β-Angelica Lactone Is Reported For The First Time.

合成参考文献


摘要:pmid:29999784
参考文献:10.1107/s1600536810034847
摘要:Benn M, Yelland LJ, Parvez M. Ranunculin. Acta Crystallogr Sect E Struct Rep Online. 2010 Sep 04;66(Pt 10):o2503.
参考文献:10.1007/bf01198410
摘要:Kroh L, Schrödter R, Mügge C, Westphal G, Baltes W, Schröder R. [Heat-induced decomposition of disaccharide Amadori compounds in quasi-water-free reaction conditions]. Z Lebensm Unters Forsch. 1992 Mar;194(3):216–21. doi: 10.1007/bf01198410.
摘要:RONDANELLI R, GIORDANO M, TROTTA N. [Thiol substances and the cytopharmacological effects of protoanemonin on karyokinesis. Experimental research]. Arch Ital Sci Farmacol. 1961 Jan;11():54–61.
参考文献:10.1016/j.bmc.2010.01.030
摘要:Senel P, Tichotová L, Votruba I, Buchta V, Spulák M, Kunes J, Nobilis M, Krenk O, Pour M. Antifungal 3,5-disubstituted furanones: From 5-acyloxymethyl to 5-alkylidene derivatives. Bioorg Med Chem. 2010 Mar 01;18(5):1988–2000. doi: 10.1016/j.bmc.2010.01.030.
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