CAS: 86-35-1; Ethotoin
物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS07;
注释: Exclamation mark - 危险类别急性毒性 类别4(经口)
- 警示词Warning(警告)
- 危险描述H302 |吞咽有害.
- 防范说明P264-P270-P330-P501
- 安全声明The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread of seizure activity rather than to abolish the primary focus of seizure discharges. Ethotoin inhibits nerve impulses in the motor cortex by lowering sodium ion influx, limiting tetanic stimulation.
- 危险类别码22
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
CAS号74-96-4 溴乙烷 | CAS号2935-35-5 (|S|)-(+)-α-苯甘氨酸 | CAS号109-90-0 异氰酸乙酯 | CAS号75-04-7 乙胺 | CAS号2835-06-5 DL-苯甘氨酸合成工艺路线路线简述
- 15028-39-4 + 17576-39-5 = 86-35-1
反应条件:1.1 Solvents: Acetonitrile,Triethylamine; 10 H,Reflux1.2 Reagents: Sodium Hydroxide; 8 H,Reflux
标题:Facile One-Pot Synthesis Of Substituted Hydantoins From Carbamates
作者:Tanwar,Dinesh Kumar; Et Al
参考文献:Synlett 日期:2017 卷标:28(17) 页码:2285-2290]
1634670-05-5 = 86-35-1
反应条件:1.1 Reagents: Pyridine Catalysts: Trifluoromethanesulfonic Anhydride Solvents: Dichloromethane; 1 Min,4 °C; 5 Min,4 °C; 4 °C -> 25 °C; 2 H,25 °C1.2 Reagents: Sodium Bicarbonate Solvents: Water
标题:Synthesis Of Highly Substituted Imidazolidine-2,4-Dione (Hydantoin) Through Tf2O-Mediated Dual Activation Of Boc-Protected Dipeptidyl Compounds
作者:Liu,Hui; Et Al
参考文献:Organic Letters 日期:2014 卷标:16(22) 页码:5902-5905]
29670-63-1 = 86-35-1
反应条件:1.1 Reagents: Hydrochloric Acid Solvents: Water; Overnight,Rt -> 120 °C2.1 -
标题:Electrocarboxylation Of N-Acylimines With Carbon Dioxide:Access To Substituted α-Amino Acids
作者:Zhang,Ke; Et Al
参考文献:Organic Letters 日期:2022 卷标:24(19) 页码:3565-3569]
71849-99-5 = 86-35-1 [标题:Reaction Conditions
标题:Electrocarboxylation Of N-Acylimines With Carbon Dioxide:Access To Substituted α-Amino Acids
作者:Zhang,Ke; Et Al
参考文献:Organic Letters 日期:2022 卷标:24(19) 页码:3565-3569]
10374-29-5 = 86-35-1
反应条件:1.1 Reagents: Tetrabutylammonium Iodide Solvents: Dimethylformamide; 4 H,1 Atm,25 °C1.2 Reagents: Hydrochloric Acid Solvents: Water2.1 Reagents: Hydrochloric Acid Solvents: Water; Overnight,Rt -> 120 °C3.1 -
标题:Electrocarboxylation Of N-Acylimines With Carbon Dioxide:Access To Substituted α-Amino Acids
作者:Zhang,Ke; Et Al
参考文献:Organic Letters 日期:2022 卷标:24(19) 页码:3565-3569]
14674-23-8 = 86-35-1
反应条件:1.1 Reagents: Cesium Carbonate,Sodium Sulfate Solvents: Dichloromethane; 25 °C2.1 Reagents: Tetrabutylammonium Iodide Solvents: Dimethylformamide; 4 H,1 Atm,25 °C2.2 Reagents: Hydrochloric Acid Solvents: Water3.1 Reagents: Hydrochloric Acid Solvents: Water; Overnight,Rt -> 120 °C4.1 -
标题:Electrocarboxylation Of N-Acylimines With Carbon Dioxide:Access To Substituted α-Amino Acids
作者:Zhang,Ke; Et Al
参考文献:Organic Letters 日期:2022 卷标:24(19) 页码:3565-3569]
55-21-0 + 100-52-7 + 657-84-1 = 86-35-1
反应条件:1.1 Solvents: Acetonitrile; Rt -> 0 °C1.2 Reagents: Chlorotrimethylsilane; 25 - 30 Min,0 °C; 24 H,0 °C -> 25 °C1.3 Solvents: Water; 30 Min2.1 Reagents: Cesium Carbonate,Sodium Sulfate Solvents: Dichloromethane; 25 °C3.1 Reagents: Tetrabutylammonium Iodide Solvents: Dimethylformamide; 4 H,1 Atm,25 °C3.2 Reagents: Hydrochloric Acid Solvents: Water4.1 Reagents: Hydrochloric Acid Solvents: Water; Overnight,Rt -> 120 °C5.1 -
标题:Electrocarboxylation Of N-Acylimines With Carbon Dioxide:Access To Substituted α-Amino Acids
作者:Zhang,Ke; Et Al
参考文献:Organic Letters 日期:2022 卷标:24(19) 页码:3565-3569
📜在 吡啶,三氟甲磺酸酐体系中,用 二氯甲烷 作为反应溶剂,化学反应 2.08H,以60%的收率获得产物乙苯妥英
参考文献:通过tf 2 O介导的boc保护的二肽化合物的双重活化合成高度取代的咪唑烷-2,4-二酮(乙内酰脲)
标题:通过tf 2 O介导的boc保护的二肽化合物的双重活化合成高度取代的咪唑烷-2,4-二酮(乙内酰脲)
摘要:高取代度的手性乙内酰脲很容易在温和的条件下一步一步由简单的二肽合成.该反应通过tf 2 O-吡啶双重活化酰胺和叔丁氧羰基(boc)保护基而进行.该方法已成功地用于制备多种生物活性化合物,包括药物类似物和天然产物.
DOI:10.1021/ol502900J
海关参考信息
- 2902600000-乙苯
2912110000-甲醛
2912120000-乙醛
2921211000-乙二胺 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2008214827-A1
优先权日:2004-02-03
标 题:Synthesis of Cyanoimino-Benzoimidazoles
发明人：GOEHRING R RICHARD; WHITEHEAD JOHN; SHAO BIN
权利人:EURO CELTIQUE SA
摘要:Disclosed in certain embodiments is a process for synthesizing a compound of formula (V) and salts thereof.
专利号:CA-2555219-A1
优先权日:2004-02-03
标 题 :Synthesis of cyanoimino-benzoimidazoles
专利号:US-8945508-B2
优先权日:2009-10-13
标 题 :Dendrimer compositions and methods of synthesis
发明人：BAKER JR JAMES R; HUANG BAOHUA
权利人:BAKER JR JAMES R; HUANG BAOHUA; UNIV MICHIGAN
摘要:The present invention relates to novel dendrimer compounds and methods of synthesizing the same. In particular, the present invention is directed to novel polyamidoamine (PAMAM) dendrimers, novel dendrimer branching units, methods for synthesizing such novel PAMAM dendrimers and functionalized dendrimers, as well as systems and methods utilizing the dendrimers (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease diagnosis and/or therapy, etc.))).
专利号:WO-2005075459-A1
优先权日:2004-02-03
标题:Synthesis of cyanoimino-benzoimidazoles
专利号:JP-2007520493-A
优先权日:2004-02-03
标 题 :Synthesis of cyanoiminobenzimidazole
专利号:US-2013030282-A1
优先权日:2011-07-18
标题:Synthesis and characterization of near ir fluorescent magnetic and non-magnetic albumin nanoparticles for biomedical applications
发明人：MARGEL SHLOMO; COHEN SARIT; SALKMON ENAV COREM; PELLACH MICHAL
权利人:UNIV BAR ILAN; MARGEL SHLOMO; COHEN SARIT; SALKMON ENAV COREM; PELLACH MICHAL
摘要:The present invention discloses Near Infrared (NIR) fluorescent albumin nanoparticles having a structure selected from a core structure or a core-shell structure. Also disclosed are a process of preparing these NIR fluorescent albumin nanoparticles, and a method of in vivo detection of pathologies, in particular cancer pathology, by using administering these NIR fluorescent albumin nanoparticles to a patient.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Hooper WD, O'Shea NJ, Qing MS. Enantioselective pharmacokinetics of ethotoin in humans following single oral doses of the racemate. Chirality. 1992;4(3):142-7. J Am Med Assoc. 1958 Jul 26;167(13):1618-20.
合成参考文献
摘要:Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2007., p. 267
摘要:Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2007., p. 259
摘要:Briggs, G.G, R.K. Freeman, S.J. Yaffe. A Reference Guide to Fetal and Neonatal Risk. Drugs in Pregnancy and Lactation. 4th ed. Baltimore, MD: Williams & Wilkins 1994., p. 358
摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664
参考文献:10.2165/00003088-199223020-00005
摘要:Murray M. P450 enzymes. Inhibition mechanisms, genetic regulation and effects of liver disease. Clin Pharmacokinet. 1992 Aug;23(2):132–46. doi: 10.2165/00003088-199223020-00005.
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尽可能描述清楚需求与问题信息
