CAS: 558-30-5; Isobutylene Oxide

上下游产品

diazomethane acetone 3-chloro-2-methylpropan-2-ol 2-chloro-2-methyl-1-propanol2-methyl-1-(piperidin-1-yl)propan-2-ol 3-(piperazin-1-yl)-2-methylpropan-2-ol 1-Methoxy-2-methylpropan-2-ol 2-methoxyisobutanol

异丁烯置于tert-Butylperoxyl Radical体系中,用 Gas 作为反应溶剂,化学反应生成 甲基环氧丙烷
参考文献:气相中氧化自由基的反应.第15部分.叔丁基过氧自由基与烯烃的反应
标题:气相中氧化自由基的反应.第15部分.叔丁基过氧自由基与烯烃的反应
摘要:研究了反式-2,2'-偶氮异丁烷与某些脂肪族烯烃混合物的光氧化反应,其反应温度为313至393K.叔丁基过氧自由基与乙烯,2-甲基丙烯,2-甲基丁-1的反应速率常数-烯,2-甲基丁-2-烯和2,3-二甲基丁-2-烯已在393 K下确定.已确定了反应(22)的阿累尼乌斯参数,用于2-甲基丁,但[图解省略] +(ch 3)3 Co 2 .->[省略图示] +(ch 3)3 Co.(22)2-烯和2,3-二甲基丁-2-烯.它们是8.16+/-0.38和8.58+/-0.61的log(a 22 / Dm 3 Mol-1 S-1)和e22 / Kj Mol-1分别为56.6+/-2.4和48.7+/-4.1.将在这项工作中获得的数据与从氢过氧基,甲基过氧基和异丙基过氧自由基系列获得的数据进行比较,并与烯烃与过乙酰基之间的加成反应获得的速率数据进行比较.
DOI:10.1039/p29840001869

专利信息

专利号:US-5110961-A
优先权日:1989-12-21
标 题:Catalytic process for the synthesis of an alcohol, new metal complexes and process for the synthesis of these complexes
发明人：LECOLIER SERGE; MORTREUX ANDRE; PETIT FRANCIS; SAMAIN HENRI
权利人:POUDRES & EXPLOSIFS STE NALE
摘要:The invention relates to a catalytic process for the synthesis of an alcohol by reaction of an epoxide with a nucleophilic compound containing a labile hydrogen, such as an alcohol, a phenol, a primary amine or a carboxylic acid. n The catalyst is a metal complex of general formula (I) n [M[Co(CO) 4 ] 2 ] x in which x is equal to 1 or 2 and M denotes tin, lead and cadmium. n The reaction preferably takes place in the presence of carbon monoxide. n This process makes it possible to increase the yield and the selectivity of the reaction and the stereoselectivity for alcohol in the case of which the hydroxyl formed is attached to the least hindered carbon atom of the epoxide. n The invention also relates to the new complexes of formula (I) in which x equals 2. n It also relates to a process for the electrosynthesis of these new compounds by electroreduction of Co 2 (CO) 8 in an organic solvent medium in a cell in which the anode consists of the metal M, followed by isolation of the complex, the temperature of the reaction mixture and that at which the complex is isolated being lower than 25° C.

专利号:US-7820838-B2
优先权日:2002-01-29
标 题:Method for total synthesis of ecteinascidins and intermediate compounds thereof
发明人：FUKUYAMA TOHRU; KAN TOSHIYUKI
权利人:JAPAN SCIENCE & TECH AGENCY
摘要:An intermediate compound for total synthesis of ecteinascidins comprising, a compound represented by general formula 2 having thioether group at C4 site, and the substituent R 2 of N 12 site is trichloroethoxycarbonyl (Troc) to which various substituents can be introduced by mild condition, further having 10 members ring structure which can be converted to a ring of other numbered members.

专利号:US-6919382-B2
优先权日:2000-08-31
标 题 :Preparation and uses of conjugated solid supports for boronic acids
发明人：HALL DENNIS G
权利人:UNIV ALBERTA
摘要:The invention provides novel solid supports comprising dihydroxyalkyl aminoalkyl and dihydroxyalkylaminobenzyl groups, and methods for making and using them. The supports are particularly useful for immobilizing and derivatizing functionalized boronic acids for use in solid phase synthesis, such as those used in combinatorial chemistries. The compositions and methods of the invention are also useful as scavenger solid supports, e.g., in solution-phase parallel synthesis of small molecule libraries, and for use in resin-to-resin transfer reactions via phase transfer of solid supported boronic acids under both aqueous and anhydrous conditions. The methods of the invention provide convergent solid-phase synthesis of symmetrically or unsymmetrically functionalized compounds, such as biphenyl compounds. Also provided are synthesizer devices, e.g., semiautomated parallel synthesizers.

专利号:WO-0009528-A1
优先权日:1998-08-13
标题:Lower alkyl ester recycling synthesis
发明人：KENNEALLY COREY JAMES; TROUT JAMES EARL; SARAMA ROBERT JOSEPH; HOWIE JOHN KEENEY
权利人:PROCTER & GAMBLE; KENNEALLY COREY JAMES; TROUT JAMES EARL; SARAMA ROBERT JOSEPH; HOWIE JOHN KEENEY
摘要:Process for synthesizing and purifying polyol fatty acids polyesters or other nondigestible fats selected from the group of esterified linked alkoxylated polyols and esterified epoxide extended polyols, in which unreacted lower alkyl ester is recovered from a reaction mixture and recycled for use in the synthesis of the nondigestible fat. The process includes the steps of reacting an excess of lower alkyl ester with polyol to esterify hydroxyl groups thereof and form polyol fatty acid polyester, separating at least a portion of the unreacted lower alkyl ester from the polyol fatty acid polyester, and recycling the separated unreacted lower alkyl ester for further reaction with polyol or partially esterified polyol. The recycled lower alkyl ester is substantially free of lower alkyl ester degradation reaction products, such as carbonyls and free fatty acids.

专利号:US-9388147-B2
优先权日:2009-11-13
标题 :Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
发明人：MARTINBOROUGH ESTHER; BOEHM MARCUS F; YEAGER ADAM RICHARD; TAMIYA JUNKO; HUANG LIMING; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA; TIMONY GREGG ALAN; BROOKS JENNIFER L; PEACH ROBERT; SCOTT FIONA LORRAINE; HANSON MICHAEL ALLEN
权利人:RECEPTOS INC; CELGENE INTERNAT II SÃ?RL
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

专利号:US-9394264-B2
优先权日:2009-11-13
标 题:Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis
发明人：MARTINBOROUGH ESTHER; BOEHM MARCUS F; YEAGER ADAM RICHARD; TAMIYA JUNKO; HUANG LIMING; BRAHMACHARY ENUGURTHI; MOORJANI MANISHA
权利人:RECEPTOS INC
摘要:Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds are provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.