CAS: 38444-73-4; 2,2',6-Trichlorobiphenyl
该化合物是一种氯化双联苯化合物,其特点是在2,2'和6个位置的三个氯替代成分,这种结构具有稳定性和抗降解性,使其在专门的工业应用中,如二电流和化学中间体中发挥作用,其界定的氯化模式允许在合成中可预见地反应,而其亲脂性有利于有机基体中的溶解性.由于监管考虑,处理需要遵守环境和安全议定书.该化合物的纯度和一致性对于需要精确化学特性的研究和特殊制造过程至关重要.适当的储存和处置措施对于减轻环境影响至关重要.
- 英文名称2,2',6-Trichlorobiphenyl
- 中文名称2,2',6-三氯联苯
- IUPAC名称1,3-dichloro-2-(2-chlorophenyl)benzene
- 其它别名2,2',6-Trichlorobiphenyl; 2,6,2'-Trichlorobiphenyl; PCB 19
- CAS编号38444-73-4
- MFCD编号:MFCD00152892
- FDA UNII编号:D412D898H3
- 分子式:C12H7Cl3分子量:257.54
- 产品CID: 1396592
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
物理性质
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
合成工艺路线路线简述
📜1,3-Dichloro-2-[(2,6-Dichlorophenyl)Methyl]-5-Methylbenzene 反应生成2,2',6-三氯联苯
参考文献:Friege,H.;Poppe,A.,Chemosphere,18,(1989) N-6,C. 1199-1206
标题:Friege,H.;Poppe,A.,Chemosphere,18,(1989) N-6,C. 1199-1206
海关参考信息
- 2903919090-氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:S116 | REFCCS | Collision Cross Section (CCS) Values from Literature | DOI:10.5281/zenodo.10932895
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. http://monographs.iarc.fr/index.php
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