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CAS号124-40-3 二甲胺 | CAS号75-78-5 二甲基二氯硅烷 | CAS号24422-23-9 1,1,1-trichloro... | CAS号18209-60-4 二甲基二甲氨基氯硅烷 | CAS号24422-24-0 1,1-dichloro-N,... | CAS号353-66-2 二氟二甲基硅烷 | CAS号2083-91-2 N-(三甲基硅烷基)二甲胺 | CAS号661-62-1 (Dimethylamino)... | CAS号18209-60-4 二甲基二甲氨基氯硅烷 | CAS号13328-30-8 N-[dichloro(dim... | CAS号24422-24-0 1,1-dichloro-N,... | CAS号13307-04-5 Silanamine, 1,1... | CAS号75-78-5 二甲基二氯硅烷 | CAS号24422-23-9 1,1,1-trichloro... | CAS号353-66-2 二氟二甲基硅烷 | CAS号2083-91-2 N-(三甲基硅烷基)二甲胺 | CAS号661-62-1 (Dimethylamino)... | CAS号1585-74-6 CHLORODIMETHYLAMINE专利信息
专利号:US-9605019-B2
优先权日:2011-07-19
标 题:Methods for the synthesis of functionalized nucleic acids
发明人:VERDINE GREGORY L; MEENA; IWAMOTO NAOKI; BUTLER DAVID CHARLES DONNELL
权利人:VERDINE GREGORY L; MEENA; IWAMOTO NAOKI; BUTLER DAVID CHARLES DONNELL; WAVE LIFE SCIENCES LTD
摘要:The present application, among other things, provides technologies, e.g., reagents, methods, etc. for preparing oligonucleotides comprising phosphorothiotriesters linkages, e.g., oligonucleotides having the structure of IIIa, IIIb or IIIc. In some embodiments, provided methods comprise reacting an H-phosphonate of structure Ia or Ib with a silylating reagent to provide a silyloxyphosphonate, and reacting the silyloxyphosphonate with a thiosulfonate reagent of structure IIa or IIb to provide an oligonucleotide of structure IIIa or IIIb. In some embodiments, provided methods comprise reacting an H-phosphonate of structure Ic with a silylating reagent to provide a silyloxyphosphonate, reacting the silyloxyphosphonate with a bis(thiosulfonate) reagent of structure IVc to provide a phosphorothiotriester comprising a thiosulfonate group of structure Vc, and then reacting the phosphorothiotriester comprising a thiosulfonate group of structure Vc with a nucleophile of structure VIc to provide an oligonucleotide of structure IIIc.
专利号:US-2022355262-A1
优先权日:2019-07-22
标题 :System and method for manufacturing water-based hydrophobic aerogels and aerogel composites
发明人:SACHITHANADAM MAHESH; KHORASGANI SOGHRATI ELMIRA; NATARAJAN GAYATHRI
权利人:KROSSLINKER PTE LTD
摘要:Embodiments of the present invention provide users with a system and method for manufacturing water-based hydrophobic aerogels and aerogel composites. The system and method can be carried out in a manner which is more rapid than typical ways and can be readily scalable. The method of manufacture is useful for producing water based hydrophobic aerogels and aerogel composites on a large scale with good homogeneity and consistency. Advantageously, the method of manufacture also has the benefit of a shorter processing time due to the vacuum homogenizing and mixing processes, the use of microwave assisted vacuum freeze drying for ease of synthesis of water-based hydrophobic aerogels.
专利号:US-2018222936-A1
优先权日:2011-07-19
标 题:Methods for the synthesis of functionalized nucleic acids
专利号:US-7402648-B2
优先权日:2004-11-05
标 题 :Method for producing cyclic organic silicon compound and organic silicon resin having alcoholic hydroxyl group
发明人:KOMURO KATSUHIKO; SUZUKI HIROSHI
权利人:TOAGOSEI CO LTD
摘要:The object of the present invention is to provide a production method wherein synthesis of a cyclic organic silicon compound similar to oxa-silacyclopentanes is completed in a single-step reaction. It is also to provide an organic silicon resin having an alcoholic hydroxyl group, which is capable of easily controlling its construction and is longitudinally stable. n The means for solving is to produce the cyclic organic silicon compound represented by the formula (3) below by reacting an olefin represented by the formula (1) below and an alkoxysilane represented by the formula (2) below in the presence of a catalyst comprising a transition metal. n n(In the formula, Z is alkenyl group having carbon atoms from 2 to 5 where the terminal carbon atom forms a Câ•?C bond, R is methyl group or hydrogen atom, and Me is methyl group.)n n n(In the formula, R 1 is alkyl group or alkoxyl group, having carbon atoms from 1 to 3, and R 2 is alkyl group having carbon atoms from 1 to 3.)n n n(In the formula, Z′ is alkylene group having carbon atoms from 2 to 5.)n n And it is an organic silicon resin having an alcoholic hydroxyl group obtained by performing hydrolysis and condensation of a cyclic organic silicon compound represented by the formula (3) above, or of a mixture of this and a polyfunctional alkoxyilane.
专利号:EP-2997074-A1
优先权日:2013-05-17
标 题 :Catalyst for synthesis of siloxanes
专利号:CA-2842358-A1
优先权日:2011-07-19
标题 :Methods for the synthesis of functionalized nucleic acids