CAS: 3401-47-6; 1-Bromo-2-Methoxynaphthalene

相似化合物

68251-77-4 62012-54-8 66996-59-6

上下游产品

CAS号93-04-9 2-萘甲醚 | CAS号573-97-7 1-溴-2-萘酚 | CAS号74-88-4 碘甲烷 | CAS号77-78-1 硫酸二甲酯 | CAS号32721-21-4 1-碘-2-甲氧基萘 | CAS号135-19-3 2-萘酚 | CAS号77-48-5 二溴海因 | CAS号7726-95-6 溴素 | CAS号64-19-7 冰醋酸 | CAS号7072-23-3 1-溴-5,5-二甲基海因 | CAS号35294-28-1 (R)-2,2’-二甲氧基-1... | CAS号75640-87-8 (S)-2,2’-二甲氧基-1... | CAS号3468-63-1 颜料橙 | CAS号141738-79-6 2-(2-methoxynap... | CAS号947-62-6 2-甲氧基-1-萘甲酸 | CAS号883-62-5 3-甲氧基-2-萘甲酸 | CAS号92643-17-9 (6-溴-2-甲氧基-1-萘基)乙腈 | CAS号2212-45-5 Naphthalene,1,1... | CAS号205-39-0 苯并[b]萘并[1,2-d]呋喃 | CAS号84167-74-8 2-乙酰基-5-溴-6-甲氧基萘

2-萘甲醚置于n-Benzyl-N,N-Dimethyl Anilinium Peroxodisulfate,Potassium Bromide体系中,用 乙腈 用作溶剂,化学反应 6.0H,以90%的收率获得1-溴-2-甲氧基萘
参考文献:Simple And Improved Regioselective Brominations Of Aromatic Compounds Using N-Benzyl N,N-Dimethyl Anilinium Peroxodisulfate In The Presence Of Potassium Bromide Under Mild Reactions Conditions
标题:Simple And Improved Regioselective Brominations Of Aromatic Compounds Using N-Benzyl N,N-Dimethyl Anilinium Peroxodisulfate In The Presence Of Potassium Bromide Under Mild Reactions Conditions
摘要:利用 N-苄基 N,N-二甲基铵选择性溴化某些活化芳香族化合物的简单,高效和温和方法 使用 N-苄基 N,N-二甲基苯胺鎓在非水溶液中进行选择性溴化某些活性芳香族化合物的简单,高效,温和的方法. 在非水溶液中,使用 N-苄基 N,N-二甲基茴香硫酸盐在溴化钾存在下选择性溴化某些活化芳香族化合物的简单,高效,温和的方法 对一些活化的芳香族化合物进行溴化.研究结果表明 在苯酚和甲氧基烯的正对位和对位之间具有非常好到卓越的选择性.
Doi:10.2298/jsc100212058G

专利信息

专利号:US-RE37813-E
优先权日:1996-02-21
标题 :Process for the synthesis of nabumetone
发明人：CANNATA VINCENZO; BERTONI AMILCARE; BIANCHI STEFANO
权利人:HONEYWELL INT INC
摘要:New process for the synthesis of the antiinflammatory drug known as nabumetone that consists in reacting 2-acetyl-5-bromo-6-methoxynaphthalene with an alkyl acetate in presence of an alkaline alcoholate to get 4-(5-bromo-6-methoxy-2-naphthyl)-4-hydroxybut-3-en-2-one that by catalytic hydrogenation in a polar solvent and in presence of a base gives 4-(6-methoxy-2-naphthyl)butan-2-one known as nabumetone.

专利号:US-5248815-A
优先权日:1991-12-27
标 题 :Stereo-selective synthesis of 2-aryl-propionic acids of high optical purity by using chiral oxazolines
发明人：PARADIES HENRICH H
权利人:PARADIES HENRICH H
摘要:The present invention relates to a stereospecific chemical synthesis of optically pure enantiomers of 2-aryl-alkanoic acids, especially those of the biologically active (S)-aryl-propionic acids, in good chemical yields, useful for preparing large quantities thereof, and having a high optical purity.

专利号:US-9908846-B2
优先权日:2014-02-21
标题:Composition, synthesis, and use of new arylsulfonyl isonitriles
发明人：FLEMING FRASER FERGUSSON; LUJAN MONTELONGO JESUS ARMANDO
权利人:DUQUESNE UNIV OF THE HOLY GHOST; UNIV HOLY GHOST DUQUESNE
摘要:This invention relates to novel isonitriles, including arylsulfonyl isonitriles, and methods for their synthesis. The isonitriles include a conjugated ring system. The structure is designed with the flexibility to have multiple substitution patterns. The isonitriles may be used in applications including, but not limited to, pharmaceutical compositions.

专利号:US-5750764-A
优先权日:1995-11-17
标题 :Synthesis and resolution of propionic acid derivatives
发明人：MARAIS STEPHANUS FRANCOIS; KHAILE THEBEEAPELO JOHN; NJAMELA OWEN LUNGILE; BRAITHWAITE DANA HELEN; DAVIDSON DEBORAH NICOLE; JUNGMANN CHRISTA MARIA; PARKINSON CHRISTOPHER JOHN; GARDINER NEIL STOCKENSTROM; STEENKAMP LUCIA HENDRINA; VAN EEDEN SKEIN ETIENNE
权利人:AECI LTD
摘要:A process for the production of disubstituted propionic acid derivatives which are intermediates in the synthesis of α-arylpropionic acids such as naproxen, involves the reaction of a naphthalene derivative such as 2-methoxynaphthalene, with an alkylating agent such as an alkyl pyruvate in the presence of a catalyst, and then dehydrating and hydrogenolising, or directly hydrogenolising, or derivatising and then hydrogenolising the product thereof, to produce the desired compound.

专利号:US-4845243-A
优先权日:1986-12-23
标 题 :Intermediates and their use in the synthesis of organic compounds
发明人：GIORDANO CLAUDIO; CASTALDI GRAZIANO
权利人:ZAMBON SPA
摘要:Compounds of formula ##STR1## (wherein Ar, R, R 1 and X have the meanings reported in the description) are useful intermediates for the preparation of a variety of organic compounds, also optically active, like alpha-haloketones, alpha-hydroxyketones or ketals, alpha-arylalkanoic acids.

专利号:EP-0178580-B1
优先权日:1984-10-15
标题:Intermediates for the synthesis of carboxylic acids
摘要:The compounds of formula: in which Ar represents an aryl, possibly substituted; R represents a C1-C4 alkyl; X represents a hydrogen, chlorine, bromine or iodine atom, a hydroxyl, or an acyloxy, alkylsulphonyloxy or arylsulphonyloxy group; n represents 0 or 1, where if n=0 one of R1 and R2 represents a -CH2OH group and the other represents a hydrogen atom, and if n=1 both R1 and R2 represent hydrogen atoms; are useful intermediates in the preparation of alpha-arylalkanoic acids by rearrangement reactions. The compounds of formula I are prepared by reacting glycerin or one of its anlogues with the appropriate alkyl-aryl-ketone.