CAS: 1668-08-2; (3S,4S,5R)-5-((S)-1,2-Dihydroxyethyl)-3,4-Dihydroxydihydrofuran-2(3H)-One

该化合物是植物和一些动物L-scobirc酸(维他命C)生物合成的关键中间体.这种甘蓝酸的环状内酯衍生物是斯密尔诺夫-惠勒途径的前体,对植物生理学和代谢研究的研究很有价值.它的高度纯度和稳定性确保了酶实验和生物化学应用的可靠性能.此外,L-Galactono-1,4-内酯还用于研究氧化性应激和抗氧化机制,因为其作用在火山生产中发挥作用.该化合物具有精确特性,质量一致,适于在学术和工业环境中进行分析和合成应用.

结构式图片

上下游产品

CAS号133-42-6 葡糖酸 | CAS号685-73-4 半乳糖醛酸 | CAS号50-81-7 抗坏血酸 | CAS号490-83-5 (L)-脱氢抗坏血酸++ | CAS号91548-32-2 3,4,5,6-tetrahy...

合成工艺路线路线简述

  • 合成目标产物 L-Galactono-1,4-Lactone 主要起始原料 D-Galacturonic Acid
  • (文献来源)合成步骤主要原料 D-Galacturonic Acid
📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于硼酸三钠,水体系中,化学反应生成半乳糖酸內酯
参考文献:Whistler,R.L.; Wolfrom,M.L.,Methods In Carbohydrate Chemistry Bd. 1 S. 127
标题:Whistler,R.L.; Wolfrom,M.L.,Methods In Carbohydrate Chemistry Bd. 1 S. 127

海关参考信息

专利信息


专利号:US-7652172-B2
优先权日:2004-09-20
标题:Expeditious synthesis of DPD
发明人:SEMMELHACK MARTIN F; CAMPAGNA SHAWN R; BASSLER BONNIE L; FEDERLE MICHAEL J
权利人:UNIV PRINCETON
摘要:This invention provides a practical synthesis route for 4,5-dihydroxypentane-2,3-dione (DPD), an unstable small molecule which is proposed to be the source of universal signaling agents for quorum sensing in bacteria. The synthesis route includes new intermediates and allows preparation of isotopically-labeled DPD and ent-DPD. The method provides sufficient quantities of DPD for study of spontaneous binding of borate to DPD, the signal for the marine bacteria V. harveyi.

专利号:US-2006084800-A1
优先权日:2004-06-30
标 题 :Synthesis of aldonolactones, aldarolactones, and aldarodilactones using azeotropic distillation
发明人:CHENAULT HENRY K
权利人:CHENAULT HENRY K
摘要:Processes for making lactones and dilactones from aldaric acids, aldonic acids, and their corresponding salts by dehydrative cyclization and azeotropic distillation. The processes can be carried out in the presence of water because water is removed by azeotropic distillation.

专利号:WO-2006005071-A1
优先权日:2004-06-30
标题:Synthesis of aldonolactones, aldarolactones, and aldarodilactones using azeotrophic distillation
发明人:CHENAULT H KEITH
权利人:DU PONT; CHENAULT H KEITH
摘要:Processes for making lactones and dilactones from aldaric acids, aldonic acids, and their corresponding salts by dehydrative cyclization and azeotropic distillation. The processes can be carried out in the presence of water because water is removed by azeotropic distillation.

专利号:US-12227788-B2
优先权日:2014-11-12
标题 :Compositions, methods and treatments for inhibiting cell adhesion and virus binding and penetration
发明人:MATTA KHUSHI L
权利人:TUMOREND LLC
摘要:Disclosed herein are glyco-decoy acceptor compositions that sidetrack or inhibit the activity of biosynthetic enzymes participating in synthesis of ligands binding at selectin, galectin and siglecs receptors; methods of their preparation and uses in drug discovery and in treatments of diseases.

专利号:US-2006084817-A1
优先权日:2004-06-30
标 题 :Synthesis of aldonolactones, aldarolactones, and aldarodilactones using gas sparging
发明人:CHENAULT HENRY K
权利人:CHENAULT HENRY K
摘要:Aldaric acids, aldonic acids, and their corresponding salts are cyclized to the corresponding lactone or dilactone using gas sparging to remove water.

专利号:US-2009018368-A1
优先权日:2004-09-20
标 题:Expeditious synthesis of dpd

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品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

参考标题:Synthesis Of Nonnatural Nucleoside Diphosphate Sugars
作者:Saskia Wolf,Rosmirt Molina Berrio,Chris Meier |发布日期:2011.11
摘要:An Efficient Chemical Method For The Synthesis Of A Variety Of Naturally Occurring Nucleoside Diphosphate (Ndp) Sugars. This Method, Which Is Based On The Cyclosal Approach, Can Also Be Used, In Principle, For The Preparation Of Rare Or Even Nonnatural Ndp Sugars. Herein, The Syntheses Of Sulfoquinovose-, Glucose-6-Sulfate-, L-Galactose-, And 2-Fluoroglycopyranoside-Containing Ndp Sugars Are Presented

合成参考文献


参考文献:10.1016/s0021-9258(19)57475-0
摘要:Majamaa K, Günzler V, Hanauske-Abel HM, Myllylä R, Kivirikko KI. Partial identity of the 2-oxoglutarate and ascorbate binding sites of prolyl 4-hydroxylase. Journal of Biological Chemistry. 1986 Jun;261(17):7819–23. doi: 10.1016/s0021-9258(19)57475-0.
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