CAS: 148546-82-1; (4-Methylpyridin-3-yl)Boronic Acid

相似化合物

1171891-31-8 874290-90-1 1428882-29-4

硼酸三异丙酯,4-甲基-3-溴吡啶置于正丁基锂,盐酸,水,Sodium Hydroxide体系中,用 四氢呋喃,甲苯,水 用作溶剂,化学反应 1.5H,以48.8%的收率获得4-甲基吡啶-3-硼酸
参考文献: Sulfonamide Compounds Useful As Cyp17 Inhibitors[fr] Composés De Sulfonamide Utiles En Tant Qu'Inhibiteurs De Cyp17
标题: Sulfonamide Compounds Useful As Cyp17 Inhibitors[fr] Composés De Sulfonamide Utiles En Tant Qu'Inhibiteurs De Cyp17
摘要:公开的是化合物的磺胺类化合物的结构式(i):或其立体异构体,N-氧化物,前药或其药学上可接受的盐,其中环a,R1,R2,R3,R4和r5在此处定义.还公开了使用这类化合物治疗与cyp17酶相关的疾病的方法,如癌症,并包括这类化合物的药物组合物.

专利信息

专利号:CN-115838378-B
优先权日:2023-02-24
标题 :Continuous Flow Synthesis of Pyridine Boronic Acids

专利号:CN-115838378-A
优先权日:2023-02-24
标题:Continuous Flow Synthesis of Pyridine Boronic Acids

专利号:US-9856241-B2
优先权日:2013-07-03
标 题:Substituted benzofuranyl and benzoxazolyl compounds and uses thereof
发明人：BALOGLU ERKAN; SHACHAM SHARON; SENAPEDIS WILLIAM; MCCAULEY DILARA; LANDESMAN YOSEF; GOLAN GALI; KALID ORI; SHECHTER SHARON
权利人:KARYOPHARM THERAPEUTICS INC
摘要:The invention generally relates to substituted benzofuranyl and substituted benzoxazolyl compounds, and more particularly to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula (A), or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of cancer (e.g., mantle cell lymphoma), and other diseases and disorders.