CAS: 1477-68-5; 3-O-Methyldopamine Hydrochloride

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📜4-羟基-3-甲氧基苄醇置于palladium On Activated Charcoal 盐酸,氢气体系中,用 乙醇,N,N-二甲基甲酰胺 用作溶剂,化学反应 32.0H,反应生成2-甲氧基-4-(2-氨基乙基)苯酚
参考文献:Syntheses Of Namda Derivatives Inhibiting No Production In Bv-2 Cells Stimulated With Lipopolysaccharide
标题:Syntheses Of Namda Derivatives Inhibiting No Production In Bv-2 Cells Stimulated With Lipopolysaccharide
摘要:Sixteen Derivatives Of N-Acetyl-3-O-Methyldopamine (Namda),An Inhibitor Of Bh4 Synthesis,Were Designed And Synthesized. The Ability Of These Derivatives To Inhibit No And Bh4 Production By Lipopolysaccharide-Stimulated Bv-2 Microglial Cells Was Determined. While Namda At 100 Mu M Inhibited No And Bh4 Production By Only About 20%,Its Catecholamide 8,Indole 23 Derivative,13,And N-Acetyl Tetrahydroisoquinoline 25 Inhibited The No Production By > 50% At The Same Concentration. In Particular,13 And 25 Inhibited Both No And Bh4 Production To Similar Degrees,Which Suggested That These Compounds Might Inhibit No Production By Blocking Bh4-Dependent Dimerization Of The Newly Synthesized Inos Monomer. (C) 2005 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2005.05.033

专利信息

专利号:US-2012016390-A1
优先权日:2010-07-16
标 题 :Bioadhesive compounds and methods of synthesis and use
发明人：LEE BRUCE P; MURPHY JOHN L; VOLLENWEIDER LAURA; DALSIN JEFFREY L; LYMAN ARINNE N
权利人:LEE BRUCE P; MURPHY JOHN L; VOLLENWEIDER LAURA; DALSIN JEFFREY L; LYMAN ARINNE N; KNC NER ACQUISITION SUB INC
摘要:The invention describes new synthetic medical adhesives and antifouling coatings which exploit the key components of natural marine mussel adhesive proteins.

专利号:WO-2012009664-A2
优先权日:2010-07-16
标 题 :Bioadhesive compounds and methods of synthesis and use

专利号:EP-2968667-A1
优先权日:2013-03-14
标题:Peg-based adhesive phenylic derivatives and methods of synthesis and use

专利号:US-2016032047-A1
优先权日:2013-03-14
标题 :Peg-based adhesive phenylic derivatives and methods of synthesis and use

专利号:CN-113416221-A
优先权日:2021-08-23
标 题 :A kind of total synthesis method of natural product phenanthrene alkaloid glycoside compound H4

专利号:CA-2905840-A1
优先权日:2013-03-14
标题 :Peg-based adhesive phenylic derivatives and methods of synthesis and use