CAS: 1460-16-8; Cycloheptane Carboxylic Acid

相似化合物

4448-75-3 32730-85-1 4277-29-6

上下游产品

cycloheptyl bromide 1,8-°Ctanedial cyclohept-1-enecarboxylic acid cyclohept-2-enecarboxylic acidmethyl cycloheptanecarboxylate cycloheptylmethanol cycloheptanecarboxamide 1-(Hydroxy-diphenyl-methyl)-cycloheptanecarboxylic acid

环辛酮置于poly(Bisanthracenyl) Diselenide,双氧水体系中,用 叔丁醇 用作溶剂,化学反应 72.0H,以36%的收率获得环庚甲酸
参考文献:环烷酮的氧化环缩合:一种合成中环环烷羧酸的简便方法
标题:环烷酮的氧化环缩合:一种合成中环环烷羧酸的简便方法
摘要:摘要 环烷酮(1)在聚(双蒽基)二硒化物(5B)作为催化剂存在下,用30%的过氧化氢氧化,生成环中比底物少一个碳原子的环烷烃羧酸(2).尽管酸 2 的制备产率不超过 60%,但该反应可作为合成具有五至七元环的环烷羧酸的简单方法.
Doi:10.1080/00397919908086230

专利信息

专利号:US-10040752-B2
优先权日:2015-08-24
标 题 :Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof
发明人：MKRTCHYAN GNEL; YAO QINGWEI
权利人:CODY LABORATORIES INC
摘要:Highly efficient methods for synthesis of levomethadone hydrochloride or dextromethadone hydrochloride are provided starting from D-alanine, or L-alanine, respectively, with retention of configuration. Methods for treating a subject are provided comprising administering a composition comprising an effective amount of levomethadone hydrochloride having not more than 10 ppm dextromethadone.

专利号:US-2013338369-A1
优先权日:2011-03-07
标 题 :Process for the Synthesis of Aminobiphenylene
发明人：HEINRICH MARKUS; PRATSCH GERALD
权利人:HEINRICH MARKUS; PRATSCH GERALD; BASF SE
摘要:The present invention relates to a process for the synthesis of 2-aminobiphenylene and derivatives thereof by reacting a benzene diazonium salt with an aniline compound under basic reaction conditions.

专利号:US-6051704-A
优先权日:1996-07-22
标题:Synthesis of macrocyclic tetraamido-N ligands
发明人：GORDON-WYLIE SCOTT W; COLLINS TERRENCE J
权利人:UNIV CARNEGIE MELLON
摘要:New synthetic methods for the preparation of macrocyclic amido-N donor ligands are provided. The primary method of the present invention involves in general only two synthetic steps. In the first step, an α or β amino carboxylic acid is allowed to react with an optimal (approximately stoichiometric) amount of an activated malonate or oxalate derivative with mild heating. Upon completion of the double coupling reaction, hydrolysis of the reaction mixture yields a diamide containing intermediate (a macro linker). In the second step, stoichiometric amounts of a diamine, preferably an orthophenylene diamine, are added to the macro linker intermediate in the presence of a coupling agent and heat. This second double coupling reaction, is allowed to proceed for a period of time sufficient to produce a macrocyclic tetraamido compound. The substituent groups on the α or β amino carboxylic acid, the malonate, and the aryl diamine may all be selectively varied so that the resulting tetraamido macrocycle can be tailored to specific desired end uses. The macrocyclic tetraamide ligand may then be complexed with a metal, such as a transition metal, and preferably the middle and later transition metals, to form a robust chelate complex suitable for catalyzing oxidation reactions.

专利号:US-5133887-A
优先权日:1988-02-24
标题:Process for the synthesis of greases permitting a good control of their mechanical behaviour and greases thus obtained
发明人：TERECH PIERRE; THIEBAUX JEAN-MARIE; SANVI PIERRE; GRUBNER CHARLES
权利人:ELF FRANCE
摘要:PCT No. PCT/FR89/00067 Sec. 371 Date Nov. 29, 1989 Sec. 102(e) Date Nov. 29, 1989 PCT Filed Feb. 22, 1989 PCT Pub. No. WO89/08139 PCT Pub. Date Sep. 8, 1989.Method for synthesizing greases by adding at least one co-surfactant to the mixture of the thickener in the oil. The addition is made at the initial stage of the formation of a three-dimensional filamentary network of the grease at a temperature between the waxy transition temperature and the melting point of the thickener. The process permits good control of the mechanical behaviour of the greases.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-6417409-B1
优先权日:1999-02-11
标 题:Process for the production of 2,3,5-trimethylhydroquinone diesters
发明人：KRILL STEFFEN; HUTHMACHER KLAUS
权利人:DEGUSSA
摘要:The invention relates to an improved process for the production of 2,3,5-trimethylhydroquinone diesters by rearrangement of 2,6,6-trimethyl-2-cyclohexene-1,4-dione (4-oxoisophorone, ketoisophorone) in the presence of a dissolved, acidic catalyst and an acylating agent, such as for example carboxylic anhydrides or carboxylic acid halides. The 2,3,5-trimethylhydroquinone diester can optionally then be saponified to give free 2,3,5-trimethylhydroquinone (TMHQ), which is a valuable building block in the synthesis of vitamin E.